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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HERV-K_8p23.1 provirus ancestral Pol protein
Full Name:
HERV-K_8p23.1 provirus ancestral Pol protein
Alias:
HERV-K115 Pol protein
Type:
Mass (Da):
107703
Number AA:
956
UniProt ID:
P63133
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
K
K
R
R
N
R
V
S
F
L
G
V
A
T
I
Site 2
T27
P
P
K
P
I
P
L
T
W
K
T
E
K
L
V
Site 3
S65
E
K
G
H
I
E
P
S
F
S
P
W
N
S
P
Site 4
S67
G
H
I
E
P
S
F
S
P
W
N
S
P
V
F
Site 5
S71
P
S
F
S
P
W
N
S
P
V
F
V
I
Q
K
Site 6
T87
S
G
K
W
R
M
L
T
D
L
R
A
V
N
A
Site 7
S108
P
L
Q
P
G
L
P
S
P
A
M
I
P
K
D
Site 8
T174
N
S
P
T
I
C
Q
T
F
V
G
R
A
L
Q
Site 9
Y191
R
K
K
F
S
D
C
Y
I
I
H
Y
I
D
D
Site 10
Y213
K
D
K
L
I
D
C
Y
T
F
L
Q
A
E
V
Site 11
S235
A
S
D
K
I
Q
T
S
T
P
F
H
Y
L
G
Site 12
T236
S
D
K
I
Q
T
S
T
P
F
H
Y
L
G
M
Site 13
T261
K
I
E
I
R
K
D
T
L
K
T
L
N
D
F
Site 14
T264
I
R
K
D
T
L
K
T
L
N
D
F
Q
K
L
Site 15
S294
Y
A
M
S
N
L
F
S
I
L
R
G
D
S
D
Site 16
S300
F
S
I
L
R
G
D
S
D
L
N
S
K
R
I
Site 17
S304
R
G
D
S
D
L
N
S
K
R
I
L
T
P
E
Site 18
T309
L
N
S
K
R
I
L
T
P
E
A
T
K
E
I
Site 19
S362
N
T
D
L
V
E
W
S
F
L
P
H
S
T
V
Site 20
S367
E
W
S
F
L
P
H
S
T
V
K
T
F
T
L
Site 21
T371
L
P
H
S
T
V
K
T
F
T
L
Y
L
D
Q
Site 22
Y435
V
G
I
I
D
N
H
Y
P
K
T
K
I
F
Q
Site 23
T465
E
P
L
E
N
A
L
T
V
F
T
D
G
S
S
Site 24
S471
L
T
V
F
T
D
G
S
S
N
G
K
A
A
Y
Site 25
Y478
S
S
N
G
K
A
A
Y
T
G
P
K
E
R
V
Site 26
T488
P
K
E
R
V
I
K
T
P
Y
Q
S
A
Q
R
Site 27
S536
E
T
A
L
I
K
Y
S
M
D
D
Q
L
N
Q
Site 28
T551
L
F
N
L
L
Q
Q
T
V
R
K
R
N
F
P
Site 29
Y560
R
K
R
N
F
P
F
Y
I
T
H
I
R
A
H
Site 30
T568
I
T
H
I
R
A
H
T
N
L
P
G
P
L
T
Site 31
T575
T
N
L
P
G
P
L
T
K
A
N
E
Q
A
D
Site 32
T655
A
L
W
Q
M
D
V
T
H
V
P
S
F
G
R
Site 33
Y665
P
S
F
G
R
L
S
Y
V
H
V
T
V
D
T
Site 34
T669
R
L
S
Y
V
H
V
T
V
D
T
Y
S
H
F
Site 35
S688
C
Q
T
G
E
S
T
S
H
V
K
K
H
L
L
Site 36
T709
G
V
P
E
K
I
K
T
D
N
G
P
G
Y
C
Site 37
Y715
K
T
D
N
G
P
G
Y
C
S
K
A
F
Q
K
Site 38
Y737
S
H
T
T
G
I
P
Y
N
S
Q
G
Q
A
I
Site 39
T754
R
T
N
R
T
L
K
T
Q
L
V
K
Q
K
E
Site 40
S765
K
Q
K
E
G
G
D
S
K
E
C
T
T
P
Q
Site 41
T769
G
G
D
S
K
E
C
T
T
P
Q
M
Q
L
N
Site 42
T770
G
D
S
K
E
C
T
T
P
Q
M
Q
L
N
L
Site 43
T792
L
N
I
Y
R
N
Q
T
T
T
S
A
E
Q
H
Site 44
T794
I
Y
R
N
Q
T
T
T
S
A
E
Q
H
L
T
Site 45
T801
T
S
A
E
Q
H
L
T
G
K
K
N
S
P
H
Site 46
S806
H
L
T
G
K
K
N
S
P
H
E
G
K
L
I
Site 47
S839
G
R
G
F
A
C
V
S
P
G
E
N
Q
L
P
Site 48
Y857
P
T
R
H
L
K
F
Y
N
E
P
I
R
D
A
Site 49
S867
P
I
R
D
A
K
K
S
T
S
A
E
T
E
T
Site 50
T872
K
K
S
T
S
A
E
T
E
T
P
Q
S
S
T
Site 51
T874
S
T
S
A
E
T
E
T
P
Q
S
S
T
V
D
Site 52
S877
A
E
T
E
T
P
Q
S
S
T
V
D
S
Q
D
Site 53
S878
E
T
E
T
P
Q
S
S
T
V
D
S
Q
D
E
Site 54
S882
P
Q
S
S
T
V
D
S
Q
D
E
Q
N
G
D
Site 55
T893
Q
N
G
D
V
R
R
T
D
E
V
A
I
H
Q
Site 56
S917
T
K
E
A
D
A
V
S
Y
K
I
S
R
E
H
Site 57
S921
D
A
V
S
Y
K
I
S
R
E
H
K
G
D
T
Site 58
T928
S
R
E
H
K
G
D
T
N
P
R
E
Y
A
A
Site 59
Y933
G
D
T
N
P
R
E
Y
A
A
C
S
L
D
D
Site 60
S937
P
R
E
Y
A
A
C
S
L
D
D
C
I
N
G
Site 61
S947
D
C
I
N
G
G
K
S
P
Y
A
C
R
S
S
Site 62
Y949
I
N
G
G
K
S
P
Y
A
C
R
S
S
C
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation