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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ERR3
Full Name:
Estrogen-related receptor gamma
Alias:
ERR gamma-2; Estrogen receptor-related protein 3; Nuclear receptor subfamily 3 group B member 3
Type:
Receptor, transcription protein. Nuclear hormone receptor family. NR3 subfamily.
Mass (Da):
51306
Number AA:
458
UniProt ID:
P62508
International Prot ID:
IPI00025743
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0050682
GO:0043565
GO:0005496
PhosphoSite+
KinaseNET
Biological Process:
GO:0045893
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
V
E
L
C
L
P
E
S
F
S
L
H
Y
E
E
Site 2
S13
L
C
L
P
E
S
F
S
L
H
Y
E
E
E
L
Site 3
Y16
P
E
S
F
S
L
H
Y
E
E
E
L
L
C
R
Site 4
S25
E
E
L
L
C
R
M
S
N
K
D
R
H
I
D
Site 5
S33
N
K
D
R
H
I
D
S
S
C
S
S
F
I
K
Site 6
S34
K
D
R
H
I
D
S
S
C
S
S
F
I
K
T
Site 7
S36
R
H
I
D
S
S
C
S
S
F
I
K
T
E
P
Site 8
S37
H
I
D
S
S
C
S
S
F
I
K
T
E
P
S
Site 9
T41
S
C
S
S
F
I
K
T
E
P
S
S
P
A
S
Site 10
S44
S
F
I
K
T
E
P
S
S
P
A
S
L
T
D
Site 11
S45
F
I
K
T
E
P
S
S
P
A
S
L
T
D
S
Site 12
S48
T
E
P
S
S
P
A
S
L
T
D
S
V
N
H
Site 13
T50
P
S
S
P
A
S
L
T
D
S
V
N
H
H
S
Site 14
S52
S
P
A
S
L
T
D
S
V
N
H
H
S
P
G
Site 15
S57
T
D
S
V
N
H
H
S
P
G
G
S
S
D
A
Site 16
S61
N
H
H
S
P
G
G
S
S
D
A
S
G
S
Y
Site 17
S62
H
H
S
P
G
G
S
S
D
A
S
G
S
Y
S
Site 18
S65
P
G
G
S
S
D
A
S
G
S
Y
S
S
T
M
Site 19
S67
G
S
S
D
A
S
G
S
Y
S
S
T
M
N
G
Site 20
S69
S
D
A
S
G
S
Y
S
S
T
M
N
G
H
Q
Site 21
T71
A
S
G
S
Y
S
S
T
M
N
G
H
Q
N
G
Site 22
S81
G
H
Q
N
G
L
D
S
P
P
L
Y
P
S
A
Site 23
S87
D
S
P
P
L
Y
P
S
A
P
I
L
G
G
S
Site 24
Y101
S
G
P
V
R
K
L
Y
D
D
C
S
S
T
I
Site 25
S105
R
K
L
Y
D
D
C
S
S
T
I
V
E
D
P
Site 26
S106
K
L
Y
D
D
C
S
S
T
I
V
E
D
P
Q
Site 27
T114
T
I
V
E
D
P
Q
T
K
C
E
Y
M
L
N
Site 28
Y118
D
P
Q
T
K
C
E
Y
M
L
N
S
M
P
K
Site 29
S122
K
C
E
Y
M
L
N
S
M
P
K
R
L
C
L
Site 30
Y140
D
I
A
S
G
Y
H
Y
G
V
A
S
C
E
A
Site 31
Y162
T
I
Q
G
N
I
E
Y
S
C
P
A
T
N
E
Site 32
T167
I
E
Y
S
C
P
A
T
N
E
C
E
I
T
K
Site 33
T173
A
T
N
E
C
E
I
T
K
R
R
R
K
S
C
Site 34
S179
I
T
K
R
R
R
K
S
C
Q
A
C
R
F
M
Site 35
Y210
V
R
G
G
R
Q
K
Y
K
R
R
I
D
A
E
Site 36
S219
R
R
I
D
A
E
N
S
P
Y
L
N
P
Q
L
Site 37
Y221
I
D
A
E
N
S
P
Y
L
N
P
Q
L
V
Q
Site 38
Y234
V
Q
P
A
K
K
P
Y
N
K
I
V
S
H
L
Site 39
Y250
V
A
E
P
E
K
I
Y
A
M
P
D
P
T
V
Site 40
T256
I
Y
A
M
P
D
P
T
V
P
D
S
D
I
K
Site 41
S260
P
D
P
T
V
P
D
S
D
I
K
A
L
T
T
Site 42
T267
S
D
I
K
A
L
T
T
L
C
D
L
A
D
R
Site 43
T291
K
H
I
P
G
F
S
T
L
S
L
A
D
Q
M
Site 44
Y326
S
F
E
D
E
L
V
Y
A
D
D
Y
I
M
D
Site 45
Y330
E
L
V
Y
A
D
D
Y
I
M
D
E
D
Q
S
Site 46
S337
Y
I
M
D
E
D
Q
S
K
L
A
G
L
L
D
Site 47
Y356
I
L
Q
L
V
K
K
Y
K
S
M
K
L
E
K
Site 48
S358
Q
L
V
K
K
Y
K
S
M
K
L
E
K
E
E
Site 49
S377
K
A
I
A
L
A
N
S
D
S
M
H
I
E
D
Site 50
S379
I
A
L
A
N
S
D
S
M
H
I
E
D
V
E
Site 51
Y402
L
H
E
A
L
Q
D
Y
E
A
G
Q
H
M
E
Site 52
T420
R
A
G
K
M
L
M
T
L
P
L
L
R
Q
T
Site 53
T427
T
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
Site 54
S428
L
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Site 55
T429
P
L
L
R
Q
T
S
T
K
A
V
Q
H
F
Y
Site 56
Y436
T
K
A
V
Q
H
F
Y
N
I
K
L
E
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation