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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TGFB2
Full Name:
Transforming growth factor beta-2
Alias:
BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Polyergin
Type:
Cell development/differentiation protein, Motility/polarity/chemotaxis
Mass (Da):
47748
Number AA:
414
UniProt ID:
P61812
International Prot ID:
IsoformA - IPI00235354
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030424
GO:0043025
GO:0031012
Uniprot
OncoNet
Molecular Function:
GO:0001540
GO:0005125
GO:0008083
PhosphoSite+
KinaseNET
Biological Process:
GO:0007184
GO:0032147
GO:0001525
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S46
A
I
R
G
Q
I
L
S
K
L
K
L
T
S
P
Site 2
T51
I
L
S
K
L
K
L
T
S
P
P
E
D
Y
P
Site 3
S52
L
S
K
L
K
L
T
S
P
P
E
D
Y
P
E
Site 4
Y57
L
T
S
P
P
E
D
Y
P
E
P
E
E
V
P
Site 5
S69
E
V
P
P
E
V
I
S
I
Y
N
S
T
R
D
Site 6
Y71
P
P
E
V
I
S
I
Y
N
S
T
R
D
L
L
Site 7
S73
E
V
I
S
I
Y
N
S
T
R
D
L
L
Q
E
Site 8
S83
D
L
L
Q
E
K
A
S
R
R
A
A
A
C
E
Site 9
S94
A
A
C
E
R
E
R
S
D
E
E
Y
Y
A
K
Site 10
Y98
R
E
R
S
D
E
E
Y
Y
A
K
E
V
Y
K
Site 11
Y104
E
Y
Y
A
K
E
V
Y
K
I
D
M
P
P
F
Site 12
S114
D
M
P
P
F
F
P
S
E
N
A
I
P
P
T
Site 13
T121
S
E
N
A
I
P
P
T
F
Y
R
P
Y
F
R
Site 14
Y123
N
A
I
P
P
T
F
Y
R
P
Y
F
R
I
V
Site 15
Y126
P
P
T
F
Y
R
P
Y
F
R
I
V
R
F
D
Site 16
S135
R
I
V
R
F
D
V
S
A
M
E
K
N
A
S
Site 17
S142
S
A
M
E
K
N
A
S
N
L
V
K
A
E
F
Site 18
Y169
P
E
Q
R
I
E
L
Y
Q
I
L
K
S
K
D
Site 19
S174
E
L
Y
Q
I
L
K
S
K
D
L
T
S
P
T
Site 20
T178
I
L
K
S
K
D
L
T
S
P
T
Q
R
Y
I
Site 21
S179
L
K
S
K
D
L
T
S
P
T
Q
R
Y
I
D
Site 22
T181
S
K
D
L
T
S
P
T
Q
R
Y
I
D
S
K
Site 23
S187
P
T
Q
R
Y
I
D
S
K
V
V
K
T
R
A
Site 24
S200
R
A
E
G
E
W
L
S
F
D
V
T
D
A
V
Site 25
Y237
T
F
V
P
S
N
N
Y
I
I
P
N
K
S
E
Site 26
S243
N
Y
I
I
P
N
K
S
E
E
L
E
A
R
F
Site 27
T256
R
F
A
G
I
D
G
T
S
T
Y
T
S
G
D
Site 28
S257
F
A
G
I
D
G
T
S
T
Y
T
S
G
D
Q
Site 29
T258
A
G
I
D
G
T
S
T
Y
T
S
G
D
Q
K
Site 30
Y259
G
I
D
G
T
S
T
Y
T
S
G
D
Q
K
T
Site 31
S261
D
G
T
S
T
Y
T
S
G
D
Q
K
T
I
K
Site 32
T266
Y
T
S
G
D
Q
K
T
I
K
S
T
R
K
K
Site 33
S269
G
D
Q
K
T
I
K
S
T
R
K
K
N
S
G
Site 34
T278
R
K
K
N
S
G
K
T
P
H
L
L
L
M
L
Site 35
Y289
L
L
M
L
L
P
S
Y
R
L
E
S
Q
Q
T
Site 36
S293
L
P
S
Y
R
L
E
S
Q
Q
T
N
R
R
K
Site 37
T296
Y
R
L
E
S
Q
Q
T
N
R
R
K
K
R
A
Site 38
Y308
K
R
A
L
D
A
A
Y
C
F
R
N
V
Q
D
Site 39
Y323
N
C
C
L
R
P
L
Y
I
D
F
K
R
D
L
Site 40
Y341
W
I
H
E
P
K
G
Y
N
A
N
F
C
A
G
Site 41
Y352
F
C
A
G
A
C
P
Y
L
W
S
S
D
T
Q
Site 42
S356
A
C
P
Y
L
W
S
S
D
T
Q
H
S
R
V
Site 43
T358
P
Y
L
W
S
S
D
T
Q
H
S
R
V
L
S
Site 44
S361
W
S
S
D
T
Q
H
S
R
V
L
S
L
Y
N
Site 45
S365
T
Q
H
S
R
V
L
S
L
Y
N
T
I
N
P
Site 46
Y367
H
S
R
V
L
S
L
Y
N
T
I
N
P
E
A
Site 47
T369
R
V
L
S
L
Y
N
T
I
N
P
E
A
S
A
Site 48
S375
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Site 49
S377
I
N
P
E
A
S
A
S
P
C
C
V
S
Q
D
Site 50
S382
S
A
S
P
C
C
V
S
Q
D
L
E
P
L
T
Site 51
T389
S
Q
D
L
E
P
L
T
I
L
Y
Y
I
G
K
Site 52
T397
I
L
Y
Y
I
G
K
T
P
K
I
E
Q
L
S
Site 53
S404
T
P
K
I
E
Q
L
S
N
M
I
V
K
S
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation