PhosphoNET

           
Protein Info 
   
Short Name:  DEFA1
Full Name:  Neutrophil defensin 1
Alias:  DEF1; DEFA2; Defensin, alpha 1; HNP-1; HNP-2; HP1; HP-1; HP2; HP-2; MRS; Neutrophil defensin 1
Type:  Secreted protein
Mass (Da):  10201
Number AA:  94
UniProt ID:  P59665
International Prot ID:  IPI00005721
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005615     Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0006935  GO:0042742  GO:0050832 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S52VSLAWDESLAPKHPG
Site 2S60LAPKHPGSRKNMACY
Site 3Y67SRKNMACYCRIPACI
Site 4Y80CIAGERRYGTCIYQG
Site 5T82AGERRYGTCIYQGRL
Site 6Y85RRYGTCIYQGRLWAF
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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