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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLF3
Full Name:
Krueppel-like factor 3
Alias:
Basic krueppel-like factor; Krueppel-like factor 3: Basic krueppel-like factor: CACCC-box-binding protein BKLF: TEF-2: Krueppel-like factor 3: Basic krueppel-like factor: CACCC-box-binding protein BKLF: TEF-2
Type:
Transcription protein
Mass (Da):
38829
Number AA:
345
UniProt ID:
P57682
International Prot ID:
IPI00027726
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
Q
E
A
M
D
P
V
S
V
S
Y
P
S
N
Y
Site 2
S20
A
M
D
P
V
S
V
S
Y
P
S
N
Y
M
E
Site 3
Y21
M
D
P
V
S
V
S
Y
P
S
N
Y
M
E
S
Site 4
S23
P
V
S
V
S
Y
P
S
N
Y
M
E
S
M
K
Site 5
Y25
S
V
S
Y
P
S
N
Y
M
E
S
M
K
P
N
Site 6
Y34
E
S
M
K
P
N
K
Y
G
V
I
Y
S
T
P
Site 7
Y38
P
N
K
Y
G
V
I
Y
S
T
P
L
P
E
K
Site 8
T40
K
Y
G
V
I
Y
S
T
P
L
P
E
K
F
F
Site 9
T49
L
P
E
K
F
F
Q
T
P
E
G
L
S
H
G
Site 10
T65
Q
M
E
P
V
D
L
T
V
N
K
R
S
S
P
Site 11
S70
D
L
T
V
N
K
R
S
S
P
P
S
A
G
N
Site 12
S71
L
T
V
N
K
R
S
S
P
P
S
A
G
N
S
Site 13
S74
N
K
R
S
S
P
P
S
A
G
N
S
P
S
S
Site 14
S78
S
P
P
S
A
G
N
S
P
S
S
L
K
F
P
Site 15
S80
P
S
A
G
N
S
P
S
S
L
K
F
P
S
S
Site 16
S81
S
A
G
N
S
P
S
S
L
K
F
P
S
S
H
Site 17
S86
P
S
S
L
K
F
P
S
S
H
R
R
A
S
P
Site 18
S87
S
S
L
K
F
P
S
S
H
R
R
A
S
P
G
Site 19
S92
P
S
S
H
R
R
A
S
P
G
L
S
M
P
S
Site 20
S96
R
R
A
S
P
G
L
S
M
P
S
S
S
P
P
Site 21
S99
S
P
G
L
S
M
P
S
S
S
P
P
I
K
K
Site 22
S100
P
G
L
S
M
P
S
S
S
P
P
I
K
K
Y
Site 23
S101
G
L
S
M
P
S
S
S
P
P
I
K
K
Y
S
Site 24
Y107
S
S
P
P
I
K
K
Y
S
P
P
S
P
G
V
Site 25
S108
S
P
P
I
K
K
Y
S
P
P
S
P
G
V
Q
Site 26
S111
I
K
K
Y
S
P
P
S
P
G
V
Q
P
F
G
Site 27
Y157
V
Q
P
V
P
F
M
Y
T
S
H
L
Q
Q
P
Site 28
S168
L
Q
Q
P
L
M
V
S
L
S
E
E
M
E
N
Site 29
S170
Q
P
L
M
V
S
L
S
E
E
M
E
N
S
S
Site 30
S176
L
S
E
E
M
E
N
S
S
S
S
M
Q
V
P
Site 31
S178
E
E
M
E
N
S
S
S
S
M
Q
V
P
V
I
Site 32
S179
E
M
E
N
S
S
S
S
M
Q
V
P
V
I
E
Site 33
Y188
Q
V
P
V
I
E
S
Y
E
K
P
I
S
Q
K
Site 34
S193
E
S
Y
E
K
P
I
S
Q
K
K
I
K
I
E
Site 35
T208
P
G
I
E
P
Q
R
T
D
Y
Y
P
E
E
M
Site 36
Y210
I
E
P
Q
R
T
D
Y
Y
P
E
E
M
S
P
Site 37
Y211
E
P
Q
R
T
D
Y
Y
P
E
E
M
S
P
P
Site 38
S216
D
Y
Y
P
E
E
M
S
P
P
L
M
N
S
V
Site 39
S222
M
S
P
P
L
M
N
S
V
S
P
P
Q
A
L
Site 40
S224
P
P
L
M
N
S
V
S
P
P
Q
A
L
L
Q
Site 41
S236
L
L
Q
E
N
H
P
S
V
I
V
Q
P
G
K
Site 42
S250
K
R
P
L
P
V
E
S
P
D
T
Q
R
K
R
Site 43
T253
L
P
V
E
S
P
D
T
Q
R
K
R
R
I
H
Site 44
Y264
R
R
I
H
R
C
D
Y
D
G
C
N
K
V
Y
Site 45
Y271
Y
D
G
C
N
K
V
Y
T
K
S
S
H
L
K
Site 46
T272
D
G
C
N
K
V
Y
T
K
S
S
H
L
K
A
Site 47
T283
H
L
K
A
H
R
R
T
H
T
G
E
K
P
Y
Site 48
T285
K
A
H
R
R
T
H
T
G
E
K
P
Y
K
C
Site 49
T308
F
A
R
S
D
E
L
T
R
H
F
R
K
H
T
Site 50
T315
T
R
H
F
R
K
H
T
G
I
K
P
F
Q
C
Site 51
S328
Q
C
P
D
C
D
R
S
F
S
R
S
D
H
L
Site 52
S330
P
D
C
D
R
S
F
S
R
S
D
H
L
A
L
Site 53
S332
C
D
R
S
F
S
R
S
D
H
L
A
L
H
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation