PhosphoNET

           
Protein Info 
   
Short Name:  SOX8
Full Name:  Transcription factor SOX-8
Alias:  MGC24837; SRY (sex determining region Y)-box 8
Type:  Nucleus protein
Mass (Da):  47314
Number AA:  446
UniProt ID:  P57073
International Prot ID:  IPI00299069
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003702  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0045944  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9LDMSEARSQPPCSPS
Site 2S14ARSQPPCSPSGTASS
Site 3S16SQPPCSPSGTASSMS
Site 4T18PPCSPSGTASSMSHV
Site 5S20CSPSGTASSMSHVED
Site 6S21SPSGTASSMSHVEDS
Site 7S23SGTASSMSHVEDSDS
Site 8S28SMSHVEDSDSDAPPS
Site 9S30SHVEDSDSDAPPSPA
Site 10S35SDSDAPPSPAGSEGL
Site 11S39APPSPAGSEGLGRAG
Site 12Y124RRKLADQYPHLHNAE
Site 13T135HNAELSKTLGKLWRL
Site 14S144GKLWRLLSESEKRPF
Site 15S146LWRLLSESEKRPFVE
Site 16Y169HKKDHPDYKYQPRRR
Site 17Y171KDHPDYKYQPRRRKS
Site 18S178YQPRRRKSAKAGHSD
Site 19S184KSAKAGHSDSDSGAE
Site 20S186AKAGHSDSDSGAELG
Site 21S188AGHSDSDSGAELGPH
Site 22Y202HPGGGAVYKAEAGLG
Site 23T218GHHHGDHTGQTHGPP
Site 24T221HGDHTGQTHGPPTPP
Site 25T226GQTHGPPTPPTTPKT
Site 26T229HGPPTPPTTPKTELQ
Site 27T230GPPTPPTTPKTELQQ
Site 28T233TPPTTPKTELQQAGA
Site 29S254EGRRPVDSGRQNIDF
Site 30S262GRQNIDFSNVDISEL
Site 31S267DFSNVDISELSSEVM
Site 32Y288DVHEFDQYLPLGGPA
Site 33Y307GQAYGGAYFHAGASP
Site 34S313AYFHAGASPVWAHKS
Site 35S320SPVWAHKSAPSASAS
Site 36S323WAHKSAPSASASPTE
Site 37S325HKSAPSASASPTETG
Site 38S327SAPSASASPTETGPP
Site 39T329PSASASPTETGPPRP
Site 40T331ASASPTETGPPRPHI
Site 41T340PPRPHIKTEQPSPGH
Site 42S344HIKTEQPSPGHYGDQ
Site 43Y348EQPSPGHYGDQPRGS
Site 44S355YGDQPRGSPDYGSCS
Site 45Y358QPRGSPDYGSCSGQS
Site 46S360RGSPDYGSCSGQSSA
Site 47S362SPDYGSCSGQSSATP
Site 48S366GSCSGQSSATPAAPA
Site 49T368CSGQSSATPAAPAGP
Site 50S379PAGPFAGSQGDYGDL
Site 51Y383FAGSQGDYGDLQASS
Site 52S389DYGDLQASSYYGAYP
Site 53S390YGDLQASSYYGAYPG
Site 54Y391GDLQASSYYGAYPGY
Site 55Y395ASSYYGAYPGYAPGL
Site 56Y398YYGAYPGYAPGLYQY
Site 57Y403PGYAPGLYQYPCFHS
Site 58Y405YAPGLYQYPCFHSPR
Site 59S410YQYPCFHSPRRPYAS
Site 60Y415FHSPRRPYASPLLNG
Site 61S417SPRRPYASPLLNGLA
Site 62S430LALPPAHSPTSHWDQ
Site 63S433PPAHSPTSHWDQPVY
Site 64Y440SHWDQPVYTTLTRP_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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