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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRDM15
Full Name:
PR domain zinc finger protein 15
Alias:
C21orf83; PFM15; PR domain zinc finger protein 15; PRD15; Zinc finger protein 298; ZNF298
Type:
Transcription regulation
Mass (Da):
169269
Number AA:
1507
UniProt ID:
P57071
International Prot ID:
IPI00025702
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
P
R
R
R
P
P
A
S
G
A
A
Q
F
P
E
Site 2
T20
Q
F
P
E
R
I
A
T
R
S
P
D
P
I
P
Site 3
S22
P
E
R
I
A
T
R
S
P
D
P
I
P
L
C
Site 4
T30
P
D
P
I
P
L
C
T
F
Q
R
Q
P
R
A
Site 5
S62
G
H
R
W
R
S
E
S
K
P
G
W
I
S
R
Site 6
S68
E
S
K
P
G
W
I
S
R
S
R
S
G
I
A
Site 7
S70
K
P
G
W
I
S
R
S
R
S
G
I
A
L
R
Site 8
S72
G
W
I
S
R
S
R
S
G
I
A
L
R
A
A
Site 9
S84
R
A
A
R
P
P
G
S
S
P
P
R
P
A
A
Site 10
S85
A
A
R
P
P
G
S
S
P
P
R
P
A
A
P
Site 11
T127
V
A
R
G
G
P
W
T
P
N
P
A
F
R
E
Site 12
S139
F
R
E
A
E
S
W
S
Q
I
G
N
Q
R
V
Site 13
S147
Q
I
G
N
Q
R
V
S
E
Q
L
L
E
T
S
Site 14
S154
S
E
Q
L
L
E
T
S
L
G
N
E
V
S
D
Site 15
S160
T
S
L
G
N
E
V
S
D
T
E
P
L
S
P
Site 16
T162
L
G
N
E
V
S
D
T
E
P
L
S
P
A
S
Site 17
S166
V
S
D
T
E
P
L
S
P
A
S
A
G
L
R
Site 18
Y217
A
G
K
A
E
C
G
Y
E
T
E
S
H
L
L
Site 19
S221
E
C
G
Y
E
T
E
S
H
L
L
E
P
H
E
Site 20
T235
E
I
P
L
N
V
N
T
H
K
F
S
D
C
E
Site 21
S271
E
G
V
W
N
Q
H
S
R
S
A
S
M
H
T
Site 22
S275
N
Q
H
S
R
S
A
S
M
H
T
F
L
N
H
Site 23
T278
S
R
S
A
S
M
H
T
F
L
N
H
S
A
T
Site 24
T285
T
F
L
N
H
S
A
T
G
I
R
E
A
G
C
Site 25
S299
C
R
K
D
M
P
V
S
E
M
A
E
D
G
S
Site 26
S323
D
C
S
Q
Y
H
D
S
E
C
P
E
L
G
P
Site 27
S341
V
K
D
S
F
V
L
S
R
A
R
S
W
P
A
Site 28
S345
F
V
L
S
R
A
R
S
W
P
A
S
G
H
V
Site 29
S349
R
A
R
S
W
P
A
S
G
H
V
H
T
Q
A
Site 30
Y363
A
G
Q
G
M
R
G
Y
E
D
R
D
R
A
D
Site 31
S387
A
G
L
V
R
R
L
S
G
Q
Q
L
P
C
R
Site 32
T396
Q
Q
L
P
C
R
S
T
L
T
W
G
R
L
C
Site 33
S412
L
V
A
Q
G
R
S
S
L
P
P
N
L
E
I
Site 34
S446
T
Q
F
G
P
F
E
S
R
R
V
A
K
W
E
Site 35
S456
V
A
K
W
E
K
E
S
A
F
P
L
K
V
F
Site 36
T498
E
A
E
H
Q
N
L
T
A
Y
Q
H
G
S
D
Site 37
Y500
E
H
Q
N
L
T
A
Y
Q
H
G
S
D
V
Y
Site 38
S504
L
T
A
Y
Q
H
G
S
D
V
Y
F
T
T
S
Site 39
Y507
Y
Q
H
G
S
D
V
Y
F
T
T
S
R
D
I
Site 40
T510
G
S
D
V
Y
F
T
T
S
R
D
I
P
P
G
Site 41
T518
S
R
D
I
P
P
G
T
E
L
R
V
W
Y
A
Site 42
Y524
G
T
E
L
R
V
W
Y
A
A
F
Y
A
K
K
Site 43
S542
P
M
L
K
Q
A
G
S
G
V
H
A
A
G
T
Site 44
T549
S
G
V
H
A
A
G
T
P
E
N
S
A
P
V
Site 45
S553
A
A
G
T
P
E
N
S
A
P
V
E
S
E
P
Site 46
S558
E
N
S
A
P
V
E
S
E
P
S
Q
W
A
C
Site 47
S561
A
P
V
E
S
E
P
S
Q
W
A
C
K
V
C
Site 48
S591
G
H
L
E
Q
A
K
S
L
P
P
G
S
Q
S
Site 49
S596
A
K
S
L
P
P
G
S
Q
S
E
A
A
A
P
Site 50
S598
S
L
P
P
G
S
Q
S
E
A
A
A
P
E
K
Site 51
T609
A
P
E
K
E
Q
D
T
P
R
G
E
P
P
A
Site 52
S620
E
P
P
A
V
P
E
S
E
N
V
A
T
K
E
Site 53
T625
P
E
S
E
N
V
A
T
K
E
Q
K
K
K
P
Site 54
S641
R
G
R
K
P
K
V
S
K
A
E
Q
P
L
V
Site 55
S673
V
P
P
D
E
P
V
S
A
T
P
D
E
R
I
Site 56
T675
P
D
E
P
V
S
A
T
P
D
E
R
I
M
E
Site 57
T692
L
G
K
L
A
T
T
T
T
D
T
S
S
V
P
Site 58
T693
G
K
L
A
T
T
T
T
D
T
S
S
V
P
K
Site 59
S696
A
T
T
T
T
D
T
S
S
V
P
K
F
T
H
Site 60
S697
T
T
T
T
D
T
S
S
V
P
K
F
T
H
H
Site 61
T710
H
H
Q
N
N
T
I
T
L
K
R
S
L
I
L
Site 62
S714
N
T
I
T
L
K
R
S
L
I
L
S
S
R
H
Site 63
S718
L
K
R
S
L
I
L
S
S
R
H
G
I
R
R
Site 64
Y738
L
G
E
H
K
R
V
Y
Q
C
N
I
C
S
K
Site 65
S750
C
S
K
I
F
Q
N
S
S
N
L
S
R
H
V
Site 66
S751
S
K
I
F
Q
N
S
S
N
L
S
R
H
V
R
Site 67
S754
F
Q
N
S
S
N
L
S
R
H
V
R
S
H
G
Site 68
S775
E
E
C
A
K
L
F
S
R
K
E
S
L
K
Q
Site 69
S779
K
L
F
S
R
K
E
S
L
K
Q
H
V
S
Y
Site 70
S785
E
S
L
K
Q
H
V
S
Y
K
H
S
R
N
E
Site 71
S789
Q
H
V
S
Y
K
H
S
R
N
E
V
D
G
E
Site 72
Y797
R
N
E
V
D
G
E
Y
R
Y
R
C
G
T
C
Site 73
Y799
E
V
D
G
E
Y
R
Y
R
C
G
T
C
E
K
Site 74
T803
E
Y
R
Y
R
C
G
T
C
E
K
T
F
R
I
Site 75
T807
R
C
G
T
C
E
K
T
F
R
I
E
S
A
L
Site 76
S812
E
K
T
F
R
I
E
S
A
L
E
F
H
N
C
Site 77
S836
E
M
C
F
R
F
F
S
T
N
S
N
L
S
K
Site 78
S842
F
S
T
N
S
N
L
S
K
H
K
K
K
H
G
Site 79
Y863
E
V
C
S
K
M
F
Y
R
K
D
V
M
L
D
Site 80
Y897
G
G
E
N
L
V
R
Y
K
K
E
P
S
G
C
Site 81
S902
V
R
Y
K
K
E
P
S
G
C
P
V
C
G
K
Site 82
Y929
L
T
H
G
D
K
K
Y
T
C
E
I
C
G
R
Site 83
S981
S
E
E
N
D
D
N
S
D
E
S
A
D
S
E
Site 84
S984
N
D
D
N
S
D
E
S
A
D
S
E
P
H
K
Site 85
S987
N
S
D
E
S
A
D
S
E
P
H
K
Y
S
C
Site 86
Y992
A
D
S
E
P
H
K
Y
S
C
K
R
C
Q
L
Site 87
T1000
S
C
K
R
C
Q
L
T
F
G
R
G
K
E
Y
Site 88
Y1007
T
F
G
R
G
K
E
Y
L
K
H
I
M
E
V
Site 89
Y1020
E
V
H
K
E
K
G
Y
G
C
S
I
C
N
R
Site 90
Y1054
P
D
P
N
V
Q
K
Y
I
H
P
C
E
I
C
Site 91
T1079
E
R
H
K
L
I
H
T
G
V
K
S
H
A
C
Site 92
Y1112
V
H
D
N
V
R
E
Y
L
C
A
E
C
G
K
Site 93
Y1140
L
H
K
G
I
K
E
Y
E
C
K
E
C
H
R
Site 94
T1163
L
K
H
C
K
R
H
T
G
I
K
D
F
M
C
Site 95
S1178
E
L
C
G
K
T
F
S
E
R
N
T
M
E
T
Site 96
T1182
K
T
F
S
E
R
N
T
M
E
T
H
K
L
I
Site 97
T1185
S
E
R
N
T
M
E
T
H
K
L
I
H
T
V
Site 98
T1191
E
T
H
K
L
I
H
T
V
G
K
Q
W
T
C
Site 99
Y1205
C
S
V
C
D
K
K
Y
V
T
E
Y
M
L
Q
Site 100
Y1209
D
K
K
Y
V
T
E
Y
M
L
Q
K
H
V
Q
Site 101
S1235
Q
L
C
G
T
K
V
S
T
R
A
S
M
S
R
Site 102
S1239
T
K
V
S
T
R
A
S
M
S
R
H
M
R
R
Site 103
T1267
D
H
L
P
E
T
T
T
I
D
A
S
S
I
G
Site 104
S1299
H
G
K
A
A
K
R
S
H
K
R
K
Q
K
P
Site 105
T1319
A
P
V
P
E
D
A
T
F
S
E
Y
S
E
K
Site 106
T1328
S
E
Y
S
E
K
E
T
E
F
T
G
S
V
G
Site 107
T1331
S
E
K
E
T
E
F
T
G
S
V
G
D
E
T
Site 108
S1333
K
E
T
E
F
T
G
S
V
G
D
E
T
N
S
Site 109
T1338
T
G
S
V
G
D
E
T
N
S
A
V
Q
S
I
Site 110
S1340
S
V
G
D
E
T
N
S
A
V
Q
S
I
Q
Q
Site 111
T1358
T
L
G
D
P
N
V
T
T
P
S
S
S
V
G
Site 112
T1359
L
G
D
P
N
V
T
T
P
S
S
S
V
G
L
Site 113
S1361
D
P
N
V
T
T
P
S
S
S
V
G
L
T
N
Site 114
S1362
P
N
V
T
T
P
S
S
S
V
G
L
T
N
I
Site 115
S1363
N
V
T
T
P
S
S
S
V
G
L
T
N
I
T
Site 116
T1395
V
A
V
G
H
L
T
T
P
E
R
Q
L
Q
L
Site 117
S1405
R
Q
L
Q
L
D
N
S
I
L
T
V
T
F
D
Site 118
S1417
T
F
D
T
V
S
G
S
A
M
L
H
N
R
Q
Site 119
S1436
I
H
P
Q
P
E
A
S
N
P
Q
S
V
A
H
Site 120
S1440
P
E
A
S
N
P
Q
S
V
A
H
F
I
N
L
Site 121
S1459
N
S
I
T
P
L
G
S
Q
L
S
D
Q
H
P
Site 122
S1462
T
P
L
G
S
Q
L
S
D
Q
H
P
L
T
W
Site 123
T1468
L
S
D
Q
H
P
L
T
W
R
A
V
P
Q
T
Site 124
T1475
T
W
R
A
V
P
Q
T
D
V
L
P
P
S
Q
Site 125
S1481
Q
T
D
V
L
P
P
S
Q
P
Q
A
P
P
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation