PhosphoNET

           
Protein Info 
   
Short Name:  SOX10
Full Name:  Transcription factor SOX-10
Alias: 
Type:  Transcription protein
Mass (Da):  49911
Number AA:  466
UniProt ID:  P56693
International Prot ID:  IPI00010781
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0042802  GO:0003713   PhosphoSite+ KinaseNET
Biological Process:  GO:0006350     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MAEEQDLSEVELSPV
Site 2S13DLSEVELSPVGSEEP
Site 3S17VELSPVGSEEPRCLS
Site 4S24SEEPRCLSPGSAPSL
Site 5S27PRCLSPGSAPSLGPD
Site 6S30LSPGSAPSLGPDGGG
Site 7S40PDGGGGGSGLRASPG
Site 8S45GGSGLRASPGPGELG
Site 9S98PVRVNGASKSKPHVK
Site 10S100RVNGASKSKPHVKRP
Site 11Y126RRKLADQYPHLHNAE
Site 12T137HNAELSKTLGKLWRL
Site 13S148LWRLLNESDKRPFIE
Site 14Y171HKKDHPDYKYQPRRR
Site 15Y173KDHPDYKYQPRRRKN
Site 16T200GEAEQGGTAAIQAHY
Site 17S221HRHPGEGSPMSDGNP
Site 18S224PGEGSPMSDGNPEHP
Site 19S232DGNPEHPSGQSHGPP
Site 20S235PEHPSGQSHGPPTPP
Site 21T240GQSHGPPTPPTTPKT
Site 22T243HGPPTPPTTPKTELQ
Site 23T244GPPTPPTTPKTELQS
Site 24T247TPPTTPKTELQSGKA
Site 25S262DPKRDGRSMGEGGKP
Site 26T291EVMSNMETFDVAELD
Site 27Y300DVAELDQYLPPNGHP
Site 28S311NGHPGHVSSYSAAGY
Site 29S312GHPGHVSSYSAAGYG
Site 30Y313HPGHVSSYSAAGYGL
Site 31S314PGHVSSYSAAGYGLG
Site 32S335SGHSAWISKPPGVAL
Site 33T360KAQVKTETAGPQGPP
Site 34Y369GPQGPPHYTDQPSTS
Site 35T370PQGPPHYTDQPSTSQ
Site 36S374PHYTDQPSTSQIAYT
Site 37S376YTDQPSTSQIAYTSL
Site 38Y380PSTSQIAYTSLSLPH
Site 39T381STSQIAYTSLSLPHY
Site 40S382TSQIAYTSLSLPHYG
Site 41S384QIAYTSLSLPHYGSA
Site 42S390LSLPHYGSAFPSISR
Site 43S394HYGSAFPSISRPQFD
Site 44S396GSAFPSISRPQFDYS
Site 45Y402ISRPQFDYSDHQPSG
Site 46S403SRPQFDYSDHQPSGP
Site 47S408DYSDHQPSGPYYGHS
Site 48Y411DHQPSGPYYGHSGQA
Site 49Y412HQPSGPYYGHSGQAS
Site 50S415SGPYYGHSGQASGLY
Site 51S419YGHSGQASGLYSAFS
Site 52Y422SGQASGLYSAFSYMG
Site 53S423GQASGLYSAFSYMGP
Site 54S426SGLYSAFSYMGPSQR
Site 55Y427GLYSAFSYMGPSQRP
Site 56S431AFSYMGPSQRPLYTA
Site 57Y436GPSQRPLYTAISDPS
Site 58T437PSQRPLYTAISDPSP
Site 59S440RPLYTAISDPSPSGP
Site 60S443YTAISDPSPSGPQSH
Site 61S445AISDPSPSGPQSHSP
Site 62S449PSPSGPQSHSPTHWE
Site 63S451PSGPQSHSPTHWEQP
Site 64T453GPQSHSPTHWEQPVY
Site 65Y460THWEQPVYTTLSRP_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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