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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TPD52
Full Name:
Tumor protein D52
Alias:
D52; HD52; N8 protein; N8L; PC-1; PrLZ; Prostate and colon associated protein; Protein N8
Type:
Endoplasmic reticulum; Calcium-binding protein
Mass (Da):
24327
Number AA:
224
UniProt ID:
P55327
International Prot ID:
IPI00218323
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0046982
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0030183
GO:0009653
GO:0046903
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
D
C
R
E
M
D
L
Y
E
D
Y
Q
S
P
F
Site 2
Y12
E
M
D
L
Y
E
D
Y
Q
S
P
F
D
F
D
Site 3
S14
D
L
Y
E
D
Y
Q
S
P
F
D
F
D
A
G
Site 4
S25
F
D
A
G
V
N
K
S
Y
L
Y
L
S
P
S
Site 5
Y26
D
A
G
V
N
K
S
Y
L
Y
L
S
P
S
G
Site 6
Y28
G
V
N
K
S
Y
L
Y
L
S
P
S
G
N
S
Site 7
S30
N
K
S
Y
L
Y
L
S
P
S
G
N
S
S
P
Site 8
S32
S
Y
L
Y
L
S
P
S
G
N
S
S
P
P
G
Site 9
S35
Y
L
S
P
S
G
N
S
S
P
P
G
S
P
T
Site 10
S36
L
S
P
S
G
N
S
S
P
P
G
S
P
T
L
Site 11
S40
G
N
S
S
P
P
G
S
P
T
L
Q
K
F
G
Site 12
T42
S
S
P
P
G
S
P
T
L
Q
K
F
G
L
L
Site 13
S66
E
D
V
A
A
T
I
S
A
T
E
T
L
S
E
Site 14
T70
A
T
I
S
A
T
E
T
L
S
E
E
E
Q
E
Site 15
S72
I
S
A
T
E
T
L
S
E
E
E
Q
E
E
L
Site 16
T92
K
V
E
E
E
I
Q
T
L
S
Q
V
L
A
A
Site 17
S94
E
E
E
I
Q
T
L
S
Q
V
L
A
A
K
E
Site 18
S115
K
R
K
L
G
I
N
S
L
Q
E
L
K
Q
N
Site 19
T131
A
K
G
W
Q
D
V
T
A
T
S
A
Y
K
K
Site 20
Y136
D
V
T
A
T
S
A
Y
K
K
T
S
E
T
L
Site 21
S140
T
S
A
Y
K
K
T
S
E
T
L
S
Q
A
G
Site 22
T142
A
Y
K
K
T
S
E
T
L
S
Q
A
G
Q
K
Site 23
S144
K
K
T
S
E
T
L
S
Q
A
G
Q
K
A
S
Site 24
S151
S
Q
A
G
Q
K
A
S
A
A
F
S
S
V
G
Site 25
S155
Q
K
A
S
A
A
F
S
S
V
G
S
V
I
T
Site 26
S156
K
A
S
A
A
F
S
S
V
G
S
V
I
T
K
Site 27
S159
A
A
F
S
S
V
G
S
V
I
T
K
K
L
E
Site 28
S171
K
L
E
D
V
K
N
S
P
T
F
K
S
F
E
Site 29
T173
E
D
V
K
N
S
P
T
F
K
S
F
E
E
K
Site 30
S176
K
N
S
P
T
F
K
S
F
E
E
K
V
E
N
Site 31
S186
E
K
V
E
N
L
K
S
K
V
G
G
T
K
P
Site 32
S204
D
F
G
E
V
L
N
S
A
A
N
A
S
A
T
Site 33
T220
T
E
P
L
P
E
K
T
Q
E
S
L
_
_
_
Site 34
S223
L
P
E
K
T
Q
E
S
L
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation