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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FOXA1
Full Name:
Hepatocyte nuclear factor 3-alpha
Alias:
Forkhead box A1; Forkhead box protein A1; Hepatocyte nuclear factor 3, alpha; HNF3A; HNF-3A; TCF3A
Type:
Transcription factor
Mass (Da):
49321
Number AA:
473
UniProt ID:
P55317
International Prot ID:
IPI00024387
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
GO:0006139
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
T
S
D
W
N
S
Y
Y
A
D
T
Q
E
A
Y
Site 2
T22
W
N
S
Y
Y
A
D
T
Q
E
A
Y
S
S
V
Site 3
S28
D
T
Q
E
A
Y
S
S
V
P
V
S
N
M
N
Site 4
S32
A
Y
S
S
V
P
V
S
N
M
N
S
G
L
G
Site 5
S36
V
P
V
S
N
M
N
S
G
L
G
S
M
N
S
Site 6
S56
T
M
N
T
M
T
T
S
G
N
M
T
P
A
S
Site 7
T60
M
T
T
S
G
N
M
T
P
A
S
F
N
M
S
Site 8
S63
S
G
N
M
T
P
A
S
F
N
M
S
Y
A
N
Site 9
S67
T
P
A
S
F
N
M
S
Y
A
N
P
A
L
G
Site 10
S123
M
G
A
Q
Q
A
A
S
M
M
N
G
L
G
P
Site 11
S189
M
A
I
Q
R
A
P
S
K
M
L
T
L
S
E
Site 12
T193
R
A
P
S
K
M
L
T
L
S
E
I
Y
Q
W
Site 13
S355
S
E
L
K
T
P
A
S
S
T
A
P
P
I
S
Site 14
S408
F
S
I
N
N
L
M
S
S
S
E
Q
Q
H
K
Site 15
T446
P
L
G
S
A
S
V
T
T
R
S
P
I
E
P
Site 16
Y460
P
S
A
L
E
P
A
Y
Y
Q
G
V
Y
S
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation