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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Peregrin
Full Name:
Peregrin
Alias:
BR140; BR140 protein; BRF1; BRPF1
Type:
Uncharacterized protein
Mass (Da):
137499
Number AA:
1214
UniProt ID:
P55201
International Prot ID:
IPI00023856
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070776
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0016563
PhosphoSite+
KinaseNET
Biological Process:
GO:0043966
GO:0045941
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
F
C
H
N
L
R
A
T
K
P
P
Y
E
C
P
Site 2
Y21
L
R
A
T
K
P
P
Y
E
C
P
V
E
T
C
Site 3
T27
P
Y
E
C
P
V
E
T
C
R
K
V
Y
K
S
Site 4
Y32
V
E
T
C
R
K
V
Y
K
S
Y
S
G
I
E
Site 5
Y35
C
R
K
V
Y
K
S
Y
S
G
I
E
Y
H
L
Site 6
S36
R
K
V
Y
K
S
Y
S
G
I
E
Y
H
L
Y
Site 7
Y40
K
S
Y
S
G
I
E
Y
H
L
Y
H
Y
D
H
Site 8
Y43
S
G
I
E
Y
H
L
Y
H
Y
D
H
D
N
P
Site 9
Y45
I
E
Y
H
L
Y
H
Y
D
H
D
N
P
P
P
Site 10
T56
N
P
P
P
P
Q
Q
T
P
L
R
K
H
K
K
Site 11
S68
H
K
K
K
G
R
Q
S
R
P
A
N
K
Q
S
Site 12
S75
S
R
P
A
N
K
Q
S
P
S
P
S
E
V
S
Site 13
S77
P
A
N
K
Q
S
P
S
P
S
E
V
S
Q
S
Site 14
S79
N
K
Q
S
P
S
P
S
E
V
S
Q
S
P
G
Site 15
S82
S
P
S
P
S
E
V
S
Q
S
P
G
R
E
V
Site 16
S84
S
P
S
E
V
S
Q
S
P
G
R
E
V
M
S
Site 17
Y92
P
G
R
E
V
M
S
Y
A
Q
A
Q
R
M
V
Site 18
S111
H
G
R
V
H
R
I
S
I
F
D
N
L
D
V
Site 19
S120
F
D
N
L
D
V
V
S
E
D
E
E
A
P
E
Site 20
T141
S
N
K
E
N
T
E
T
P
A
A
T
P
K
S
Site 21
T145
N
T
E
T
P
A
A
T
P
K
S
G
K
H
K
Site 22
S148
T
P
A
A
T
P
K
S
G
K
H
K
N
K
E
Site 23
S171
H
H
H
N
V
S
A
S
T
T
P
K
L
P
E
Site 24
T173
H
N
V
S
A
S
T
T
P
K
L
P
E
V
V
Site 25
T188
Y
R
E
L
E
Q
D
T
P
D
A
P
P
R
P
Site 26
T196
P
D
A
P
P
R
P
T
S
Y
Y
R
Y
I
E
Site 27
S197
D
A
P
P
R
P
T
S
Y
Y
R
Y
I
E
K
Site 28
Y198
A
P
P
R
P
T
S
Y
Y
R
Y
I
E
K
S
Site 29
Y199
P
P
R
P
T
S
Y
Y
R
Y
I
E
K
S
A
Site 30
Y201
R
P
T
S
Y
Y
R
Y
I
E
K
S
A
E
E
Site 31
S205
Y
Y
R
Y
I
E
K
S
A
E
E
L
D
E
E
Site 32
Y215
E
L
D
E
E
V
E
Y
D
M
D
E
E
D
Y
Site 33
Y222
Y
D
M
D
E
E
D
Y
I
W
L
D
I
M
N
Site 34
T234
I
M
N
E
R
R
K
T
E
G
V
S
P
I
P
Site 35
S238
R
R
K
T
E
G
V
S
P
I
P
Q
E
I
F
Site 36
Y247
I
P
Q
E
I
F
E
Y
L
M
D
R
L
E
K
Site 37
S256
M
D
R
L
E
K
E
S
Y
F
E
S
H
N
K
Site 38
Y257
D
R
L
E
K
E
S
Y
F
E
S
H
N
K
G
Site 39
S260
E
K
E
S
Y
F
E
S
H
N
K
G
D
P
N
Site 40
Y309
Q
E
C
Y
G
V
P
Y
I
P
E
G
Q
W
L
Site 41
S323
L
C
R
R
C
L
Q
S
P
S
R
A
V
D
C
Site 42
S325
R
R
C
L
Q
S
P
S
R
A
V
D
C
A
L
Site 43
T343
K
G
G
A
F
K
Q
T
D
D
G
R
W
A
H
Site 44
Y387
A
R
W
K
L
T
C
Y
I
C
K
Q
R
G
S
Site 45
Y420
C
A
Q
Q
A
G
L
Y
M
K
M
E
P
V
R
Site 46
T429
K
M
E
P
V
R
E
T
G
A
N
G
T
S
F
Site 47
T434
R
E
T
G
A
N
G
T
S
F
S
V
R
K
T
Site 48
S435
E
T
G
A
N
G
T
S
F
S
V
R
K
T
A
Site 49
S437
G
A
N
G
T
S
F
S
V
R
K
T
A
Y
C
Site 50
T441
T
S
F
S
V
R
K
T
A
Y
C
D
I
H
T
Site 51
T448
T
A
Y
C
D
I
H
T
P
P
G
S
A
R
R
Site 52
S452
D
I
H
T
P
P
G
S
A
R
R
L
P
A
L
Site 53
S460
A
R
R
L
P
A
L
S
H
S
E
G
E
E
D
Site 54
S462
R
L
P
A
L
S
H
S
E
G
E
E
D
E
D
Site 55
S490
V
K
K
A
K
A
K
S
R
I
K
M
K
K
A
Site 56
S522
C
I
P
P
H
R
L
S
K
I
T
N
R
L
T
Site 57
T525
P
H
R
L
S
K
I
T
N
R
L
T
I
Q
R
Site 58
T529
S
K
I
T
N
R
L
T
I
Q
R
K
S
Q
F
Site 59
S534
R
L
T
I
Q
R
K
S
Q
F
M
Q
R
L
H
Site 60
S542
Q
F
M
Q
R
L
H
S
Y
W
T
L
K
R
Q
Site 61
T545
Q
R
L
H
S
Y
W
T
L
K
R
Q
S
R
N
Site 62
S550
Y
W
T
L
K
R
Q
S
R
N
G
V
P
L
L
Site 63
T562
P
L
L
R
R
L
Q
T
H
L
Q
S
Q
R
N
Site 64
S566
R
L
Q
T
H
L
Q
S
Q
R
N
C
D
Q
V
Site 65
S577
C
D
Q
V
G
R
D
S
E
D
K
N
W
A
L
Site 66
S590
A
L
K
E
Q
L
K
S
W
Q
R
L
R
H
D
Site 67
T618
R
E
K
L
K
R
E
T
I
K
V
Q
Q
I
A
Site 68
T640
F
L
I
L
L
R
K
T
L
E
Q
L
Q
E
K
Site 69
T649
E
Q
L
Q
E
K
D
T
G
N
I
F
S
E
P
Site 70
S654
K
D
T
G
N
I
F
S
E
P
V
P
L
S
E
Site 71
S660
F
S
E
P
V
P
L
S
E
V
P
D
Y
L
D
Site 72
Y665
P
L
S
E
V
P
D
Y
L
D
H
I
K
K
P
Site 73
T677
K
K
P
M
D
F
F
T
M
K
Q
N
L
E
A
Site 74
Y687
Q
N
L
E
A
Y
R
Y
L
N
F
D
D
F
E
Site 75
S752
T
G
M
H
I
P
H
S
L
A
G
D
E
A
T
Site 76
S799
R
L
D
E
V
N
A
S
K
Q
S
V
G
R
S
Site 77
S802
E
V
N
A
S
K
Q
S
V
G
R
S
R
R
A
Site 78
S806
S
K
Q
S
V
G
R
S
R
R
A
K
M
I
K
Site 79
T829
K
L
A
H
Q
R
E
T
G
R
D
G
P
E
R
Site 80
S840
G
P
E
R
H
G
P
S
S
R
G
S
L
T
P
Site 81
S841
P
E
R
H
G
P
S
S
R
G
S
L
T
P
H
Site 82
S844
H
G
P
S
S
R
G
S
L
T
P
H
P
A
A
Site 83
T846
P
S
S
R
G
S
L
T
P
H
P
A
A
C
D
Site 84
T858
A
C
D
K
D
G
Q
T
D
S
A
A
E
E
S
Site 85
S860
D
K
D
G
Q
T
D
S
A
A
E
E
S
S
S
Site 86
S867
S
A
A
E
E
S
S
S
Q
E
T
S
K
G
L
Site 87
S871
E
S
S
S
Q
E
T
S
K
G
L
G
P
N
M
Site 88
S879
K
G
L
G
P
N
M
S
S
T
P
A
H
E
V
Site 89
S880
G
L
G
P
N
M
S
S
T
P
A
H
E
V
G
Site 90
T881
L
G
P
N
M
S
S
T
P
A
H
E
V
G
R
Site 91
T890
A
H
E
V
G
R
R
T
S
V
L
F
S
K
K
Site 92
S891
H
E
V
G
R
R
T
S
V
L
F
S
K
K
N
Site 93
S895
R
R
T
S
V
L
F
S
K
K
N
P
K
T
A
Site 94
T901
F
S
K
K
N
P
K
T
A
G
P
P
K
R
P
Site 95
S917
R
P
P
K
N
R
E
S
Q
M
T
P
S
H
G
Site 96
T920
K
N
R
E
S
Q
M
T
P
S
H
G
G
S
P
Site 97
S922
R
E
S
Q
M
T
P
S
H
G
G
S
P
V
G
Site 98
S926
M
T
P
S
H
G
G
S
P
V
G
P
P
Q
L
Site 99
S938
P
Q
L
P
I
M
S
S
L
R
Q
R
K
R
G
Site 100
S947
R
Q
R
K
R
G
R
S
P
R
P
S
S
S
S
Site 101
S951
R
G
R
S
P
R
P
S
S
S
S
D
S
D
S
Site 102
S952
G
R
S
P
R
P
S
S
S
S
D
S
D
S
D
Site 103
S953
R
S
P
R
P
S
S
S
S
D
S
D
S
D
K
Site 104
S954
S
P
R
P
S
S
S
S
D
S
D
S
D
K
S
Site 105
S956
R
P
S
S
S
S
D
S
D
S
D
K
S
T
E
Site 106
S958
S
S
S
S
D
S
D
S
D
K
S
T
E
D
P
Site 107
S961
S
D
S
D
S
D
K
S
T
E
D
P
P
M
D
Site 108
T962
D
S
D
S
D
K
S
T
E
D
P
P
M
D
L
Site 109
S984
G
N
Q
P
V
K
K
S
F
L
V
Y
R
N
D
Site 110
Y988
V
K
K
S
F
L
V
Y
R
N
D
C
S
L
P
Site 111
S993
L
V
Y
R
N
D
C
S
L
P
R
S
S
S
D
Site 112
S997
N
D
C
S
L
P
R
S
S
S
D
S
E
S
S
Site 113
S998
D
C
S
L
P
R
S
S
S
D
S
E
S
S
S
Site 114
S999
C
S
L
P
R
S
S
S
D
S
E
S
S
S
S
Site 115
S1001
L
P
R
S
S
S
D
S
E
S
S
S
S
S
S
Site 116
S1003
R
S
S
S
D
S
E
S
S
S
S
S
S
S
S
Site 117
S1004
S
S
S
D
S
E
S
S
S
S
S
S
S
S
A
Site 118
S1005
S
S
D
S
E
S
S
S
S
S
S
S
S
A
A
Site 119
S1006
S
D
S
E
S
S
S
S
S
S
S
S
A
A
S
Site 120
S1007
D
S
E
S
S
S
S
S
S
S
S
A
A
S
D
Site 121
S1008
S
E
S
S
S
S
S
S
S
S
A
A
S
D
R
Site 122
S1009
E
S
S
S
S
S
S
S
S
A
A
S
D
R
T
Site 123
S1010
S
S
S
S
S
S
S
S
A
A
S
D
R
T
S
Site 124
S1013
S
S
S
S
S
A
A
S
D
R
T
S
T
T
P
Site 125
S1017
S
A
A
S
D
R
T
S
T
T
P
S
K
Q
G
Site 126
T1018
A
A
S
D
R
T
S
T
T
P
S
K
Q
G
R
Site 127
T1019
A
S
D
R
T
S
T
T
P
S
K
Q
G
R
G
Site 128
S1021
D
R
T
S
T
T
P
S
K
Q
G
R
G
K
P
Site 129
S1029
K
Q
G
R
G
K
P
S
F
S
R
G
T
F
P
Site 130
S1031
G
R
G
K
P
S
F
S
R
G
T
F
P
E
D
Site 131
T1034
K
P
S
F
S
R
G
T
F
P
E
D
S
S
E
Site 132
S1039
R
G
T
F
P
E
D
S
S
E
D
T
S
G
T
Site 133
S1040
G
T
F
P
E
D
S
S
E
D
T
S
G
T
E
Site 134
T1043
P
E
D
S
S
E
D
T
S
G
T
E
N
E
A
Site 135
S1044
E
D
S
S
E
D
T
S
G
T
E
N
E
A
Y
Site 136
T1046
S
S
E
D
T
S
G
T
E
N
E
A
Y
S
V
Site 137
Y1051
S
G
T
E
N
E
A
Y
S
V
G
T
G
R
G
Site 138
S1052
G
T
E
N
E
A
Y
S
V
G
T
G
R
G
V
Site 139
S1062
T
G
R
G
V
G
H
S
M
V
R
K
S
L
G
Site 140
S1067
G
H
S
M
V
R
K
S
L
G
R
G
A
G
W
Site 141
S1076
G
R
G
A
G
W
L
S
E
D
E
D
S
P
L
Site 142
S1081
W
L
S
E
D
E
D
S
P
L
D
A
L
D
L
Site 143
S1098
A
K
C
R
G
Y
P
S
Y
P
A
L
I
I
D
Site 144
Y1099
K
C
R
G
Y
P
S
Y
P
A
L
I
I
D
P
Site 145
T1135
L
K
L
G
E
Q
M
T
Q
E
A
R
E
H
L
Site 146
Y1143
Q
E
A
R
E
H
L
Y
L
V
L
F
F
D
N
Site 147
S1182
K
M
L
E
G
R
K
S
N
I
R
K
S
V
Q
Site 148
S1187
R
K
S
N
I
R
K
S
V
Q
I
A
Y
H
R
Site 149
Y1192
R
K
S
V
Q
I
A
Y
H
R
A
L
Q
H
R
Site 150
S1207
S
K
V
Q
G
E
Q
S
S
E
T
S
D
S
D
Site 151
S1208
K
V
Q
G
E
Q
S
S
E
T
S
D
S
D
_
Site 152
S1211
G
E
Q
S
S
E
T
S
D
S
D
_
_
_
_
Site 153
S1213
Q
S
S
E
T
S
D
S
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation