PhosphoNET

           
Protein Info 
   
Short Name:  MLLT6
Full Name:  Protein AF-17
Alias:  AF17; AF-17; ALL1 fused gene from chromosome 17 protein; FLJ23480; Myeloid/lymphoid or mixed-lineage leukemia (trithorax) translocated to, 6; Myeloid/lymphoid or mixed-lineage leukemia (trithorax) translocated to, 6 (AF17); Myeloid/lymphoid or mixed-lineage leukemia, translocated to, 6; Trithorax
Type:  Transcription factor
Mass (Da):  112076
Number AA:  1093
UniProt ID:  P55198
International Prot ID:  IPI00023466
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005739  GO:0005634  GO:0043227 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0008270  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0009889  GO:0010468 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y110MEPIVLQYVPHDRFN
Site 2Y121DRFNKTCYICEEQGR
Site 3S130CEEQGRESKAASGAC
Site 4S134GRESKAASGACMTCN
Site 5Y173LEVDNVKYCGYCKYH
Site 6T186YHFSKMKTSRHSSGG
Site 7S187HFSKMKTSRHSSGGG
Site 8S190KMKTSRHSSGGGGGG
Site 9S191MKTSRHSSGGGGGGA
Site 10S204GAGGGGGSMGGGGSG
Site 11S210GSMGGGGSGFISGRR
Site 12S214GGGSGFISGRRSRSA
Site 13S218GFISGRRSRSASPST
Site 14S220ISGRRSRSASPSTQQ
Site 15S222GRRSRSASPSTQQEK
Site 16S224RSRSASPSTQQEKHP
Site 17T232TQQEKHPTHHERGQK
Site 18S241HERGQKKSRKDKERL
Site 19S258KHKKRPESPPSILTP
Site 20S261KRPESPPSILTPPVV
Site 21S275VPTADKVSSSASSSS
Site 22S276PTADKVSSSASSSSH
Site 23S277TADKVSSSASSSSHH
Site 24S279DKVSSSASSSSHHEA
Site 25S280KVSSSASSSSHHEAS
Site 26S281VSSSASSSSHHEAST
Site 27S282SSSASSSSHHEASTQ
Site 28S287SSSHHEASTQETSES
Site 29T288SSHHEASTQETSESS
Site 30T291HEASTQETSESSRES
Site 31S292EASTQETSESSRESK
Site 32S294STQETSESSRESKGK
Site 33S298TSESSRESKGKKSSS
Site 34S303RESKGKKSSSHSLSH
Site 35S304ESKGKKSSSHSLSHK
Site 36S305SKGKKSSSHSLSHKG
Site 37S307GKKSSSHSLSHKGKK
Site 38S309KSSSHSLSHKGKKLS
Site 39S316SHKGKKLSSGKGVSS
Site 40S317HKGKKLSSGKGVSSF
Site 41S322LSSGKGVSSFTSASS
Site 42S323SSGKGVSSFTSASSS
Site 43T325GKGVSSFTSASSSSS
Site 44S326KGVSSFTSASSSSSS
Site 45S328VSSFTSASSSSSSSS
Site 46S329SSFTSASSSSSSSSS
Site 47S330SFTSASSSSSSSSSS
Site 48S331FTSASSSSSSSSSSS
Site 49S332TSASSSSSSSSSSSG
Site 50S333SASSSSSSSSSSSGG
Site 51S334ASSSSSSSSSSSGGP
Site 52S335SSSSSSSSSSSGGPF
Site 53S336SSSSSSSSSSGGPFQ
Site 54S337SSSSSSSSSGGPFQP
Site 55S338SSSSSSSSGGPFQPA
Site 56S347GPFQPAVSSLQSSPD
Site 57S348PFQPAVSSLQSSPDF
Site 58S351PAVSSLQSSPDFSAF
Site 59S352AVSSLQSSPDFSAFP
Site 60S356LQSSPDFSAFPKLEQ
Site 61Y369EQPEEDKYSKPTAPA
Site 62S370QPEEDKYSKPTAPAP
Site 63S378KPTAPAPSAPPSPSA
Site 64S382PAPSAPPSPSAPEPP
Site 65S384PSAPPSPSAPEPPKA
Site 66S410FGPIMRFSTTTSSSG
Site 67T411GPIMRFSTTTSSSGR
Site 68T412PIMRFSTTTSSSGRA
Site 69T413IMRFSTTTSSSGRAR
Site 70S414MRFSTTTSSSGRARA
Site 71S415RFSTTTSSSGRARAP
Site 72S416FSTTTSSSGRARAPS
Site 73S423SGRARAPSPGDYKSP
Site 74Y427RAPSPGDYKSPHVTG
Site 75S429PSPGDYKSPHVTGSG
Site 76T433DYKSPHVTGSGASAG
Site 77S435KSPHVTGSGASAGTH
Site 78S449HKRMPALSATPVPAD
Site 79T451RMPALSATPVPADET
Site 80T458TPVPADETPETGLKE
Site 81T461PADETPETGLKEKKH
Site 82S471KEKKHKASKRSRHGP
Site 83S484GPGRPKGSRNKEGTG
Site 84T490GSRNKEGTGGPAAPS
Site 85S528SSGLGGLSSRTFGPS
Site 86S529SGLGGLSSRTFGPSG
Site 87T531LGGLSSRTFGPSGSL
Site 88S535SSRTFGPSGSLPSLS
Site 89S537RTFGPSGSLPSLSLE
Site 90S540GPSGSLPSLSLESPL
Site 91Y553PLLGAGIYTSNKDPI
Site 92S555LGAGIYTSNKDPISH
Site 93S561TSNKDPISHSGGMLR
Site 94S578CSTPLSSSLLGPPGT
Site 95S586LLGPPGTSALPRLSR
Site 96S592TSALPRLSRSPFTST
Site 97S594ALPRLSRSPFTSTLP
Site 98T597RLSRSPFTSTLPSSS
Site 99S598LSRSPFTSTLPSSSA
Site 100T599SRSPFTSTLPSSSAS
Site 101S602PFTSTLPSSSASIST
Site 102S603FTSTLPSSSASISTT
Site 103S604TSTLPSSSASISTTQ
Site 104S624GSTFSLPSTHIFGTP
Site 105T630PSTHIFGTPMGAVNP
Site 106S640GAVNPLLSQAESSHT
Site 107S644PLLSQAESSHTEPDL
Site 108T647SQAESSHTEPDLEDC
Site 109S655EPDLEDCSFRCRGTS
Site 110T661CSFRCRGTSPQESLS
Site 111S662SFRCRGTSPQESLSS
Site 112S666RGTSPQESLSSMSPI
Site 113S668TSPQESLSSMSPISS
Site 114S669SPQESLSSMSPISSL
Site 115S671QESLSSMSPISSLPA
Site 116S675SSMSPISSLPALFDQ
Site 117S685ALFDQTASAPCGGGQ
Site 118S742RLQEQILSLTAKKER
Site 119Y779NGPVPGPYGLPPQAG
Site 120S787GLPPQAGSSDSLSTS
Site 121S788LPPQAGSSDSLSTSK
Site 122S790PQAGSSDSLSTSKSP
Site 123S792AGSSDSLSTSKSPPG
Site 124S794SSDSLSTSKSPPGKS
Site 125S796DSLSTSKSPPGKSSL
Site 126S801SKSPPGKSSLGLDNS
Site 127S802KSPPGKSSLGLDNSL
Site 128S808SSLGLDNSLSTSSED
Site 129S810LGLDNSLSTSSEDPH
Site 130S812LDNSLSTSSEDPHSG
Site 131S813DNSLSTSSEDPHSGC
Site 132S818TSSEDPHSGCPSRSS
Site 133S822DPHSGCPSRSSSSLS
Site 134S824HSGCPSRSSSSLSFH
Site 135S825SGCPSRSSSSLSFHS
Site 136S826GCPSRSSSSLSFHST
Site 137S827CPSRSSSSLSFHSTP
Site 138S829SRSSSSLSFHSTPPP
Site 139S832SSSLSFHSTPPPLPL
Site 140S913AAAPNPASLSQAGGA
Site 141S915APNPASLSQAGGAPT
Site 142S931QLPGCLNSLTEQQRH
Site 143T933PGCLNSLTEQQRHLL
Site 144S956QLQQLLASPQLTPEH
Site 145Y968PEHQTVVYQMIQQIQ
Site 146S1066AQTNPFLSLSGAEGS
Site 147S1068TNPFLSLSGAEGSGG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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