PhosphoNET

           
Protein Info 
   
Short Name:  FGF8
Full Name:  Fibroblast growth factor 8
Alias:  Androgen-induced growth factor;Heparin-binding growth factor 8
Type: 
Mass (Da):  26525
Number AA:  233
UniProt ID:  P55075
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S38ALGRELASLFRAGRE
Site 2S58QQHVREQSLVTDQLS
Site 3S65SLVTDQLSRRLIRTY
Site 4T71LSRRLIRTYQLYSRT
Site 5Y72SRRLIRTYQLYSRTS
Site 6Y75LIRTYQLYSRTSGKH
Site 7S79YQLYSRTSGKHVQVL
Site 8T110KLIVETDTFGSRVRV
Site 9S113VETDTFGSRVRVRGA
Site 10T122VRVRGAETGLYICMN
Site 11Y125RGAETGLYICMNKKG
Site 12S138KGKLIAKSNGKGKDC
Site 13T157IVLENNYTALQNAKY
Site 14Y164TALQNAKYEGWYMAF
Site 15S181KGRPRKGSKTRQHQR
Site 16T183RPRKGSKTRQHQREV
Site 17T202RLPRGHHTTEQSLRF
Site 18T203LPRGHHTTEQSLRFE
Site 19S206GHHTTEQSLRFEFLN
Site 20Y214LRFEFLNYPPFTRSL
Site 21S220NYPPFTRSLRGSQRT
Site 22S224FTRSLRGSQRTWAPE
Site 23T227SLRGSQRTWAPEPR_
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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