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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CSE1L
Full Name:
Exportin-2
Alias:
Exp2
Type:
Mass (Da):
110399
Number AA:
971
UniProt ID:
P55060
International Prot ID:
IPI00022744
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005643
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005049
GO:0005215
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0000059
GO:0006461
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
D
A
N
L
Q
T
L
T
E
Y
L
K
K
T
L
Site 2
Y14
N
L
Q
T
L
T
E
Y
L
K
K
T
L
D
P
Site 3
T18
L
T
E
Y
L
K
K
T
L
D
P
D
P
A
I
Site 4
S35
P
A
E
K
F
L
E
S
V
E
G
N
Q
N
Y
Site 5
T48
N
Y
P
L
L
L
L
T
L
L
E
K
S
Q
D
Site 6
S103
I
V
H
L
M
L
S
S
P
E
Q
I
Q
K
Q
Site 7
S112
E
Q
I
Q
K
Q
L
S
D
A
I
S
I
I
G
Site 8
S116
K
Q
L
S
D
A
I
S
I
I
G
R
E
D
F
Site 9
S155
G
V
L
R
T
A
H
S
L
F
K
R
Y
R
H
Site 10
T197
A
T
I
E
L
C
S
T
H
A
N
D
A
S
A
Site 11
S203
S
T
H
A
N
D
A
S
A
L
R
I
L
F
S
Site 12
T247
N
N
F
H
T
L
L
T
L
D
N
K
L
L
Q
Site 13
Y282
A
A
L
Y
A
Q
K
Y
D
E
E
F
Q
R
Y
Site 14
Y289
Y
D
E
E
F
Q
R
Y
L
P
R
F
V
T
A
Site 15
Y310
T
T
G
Q
E
V
K
Y
D
L
L
V
S
N
A
Site 16
Y330
S
V
C
E
R
P
H
Y
K
N
L
F
E
D
Q
Site 17
T339
N
L
F
E
D
Q
N
T
L
T
S
I
C
E
K
Site 18
S366
E
E
A
F
E
D
N
S
E
E
Y
I
R
R
D
Site 19
Y369
F
E
D
N
S
E
E
Y
I
R
R
D
L
E
G
Site 20
S377
I
R
R
D
L
E
G
S
D
I
D
T
R
R
R
Site 21
T381
L
E
G
S
D
I
D
T
R
R
R
A
A
C
D
Site 22
Y408
V
T
G
I
F
S
G
Y
V
N
S
M
L
Q
E
Site 23
T443
S
L
A
S
K
A
Q
T
Q
K
H
G
I
T
Q
Site 24
S471
H
I
L
P
D
L
K
S
A
N
V
N
E
F
P
Site 25
Y487
L
K
A
D
G
I
K
Y
I
M
I
F
R
N
Q
Site 26
T531
H
A
L
E
R
L
F
T
M
R
G
P
N
N
A
Site 27
T562
T
N
L
F
K
A
L
T
L
P
G
S
S
E
N
Site 28
S566
K
A
L
T
L
P
G
S
S
E
N
E
Y
I
M
Site 29
S567
A
L
T
L
P
G
S
S
E
N
E
Y
I
M
K
Site 30
Y571
P
G
S
S
E
N
E
Y
I
M
K
A
I
M
R
Site 31
S606
T
Q
K
L
L
A
V
S
K
N
P
S
K
P
H
Site 32
S610
L
A
V
S
K
N
P
S
K
P
H
F
N
H
Y
Site 33
S680
T
H
K
N
D
I
P
S
S
Y
M
A
L
F
P
Site 34
Y682
K
N
D
I
P
S
S
Y
M
A
L
F
P
H
L
Site 35
S716
Q
A
F
L
E
R
G
S
N
T
I
A
S
A
A
Site 36
Y749
A
N
D
H
Q
G
F
Y
L
L
N
S
I
I
E
Site 37
S762
I
E
H
M
P
P
E
S
V
D
Q
Y
R
K
Q
Site 38
Y766
P
P
E
S
V
D
Q
Y
R
K
Q
I
F
I
L
Site 39
S781
L
F
Q
R
L
Q
N
S
K
T
T
K
F
I
K
Site 40
T783
Q
R
L
Q
N
S
K
T
T
K
F
I
K
S
F
Site 41
Y861
P
P
M
M
D
T
E
Y
T
K
L
W
T
P
L
Site 42
T883
F
E
L
P
E
D
D
T
I
P
D
E
E
H
F
Site 43
T896
H
F
I
D
I
E
D
T
P
G
Y
Q
T
A
F
Site 44
Y899
D
I
E
D
T
P
G
Y
Q
T
A
F
S
Q
L
Site 45
S904
P
G
Y
Q
T
A
F
S
Q
L
A
F
A
G
K
Site 46
S931
P
K
I
H
L
A
Q
S
L
H
K
L
S
T
A
Site 47
S936
A
Q
S
L
H
K
L
S
T
A
C
P
G
R
V
Site 48
T937
Q
S
L
H
K
L
S
T
A
C
P
G
R
V
P
Site 49
S945
A
C
P
G
R
V
P
S
M
V
S
T
S
L
N
Site 50
Y958
L
N
A
E
A
L
Q
Y
L
Q
G
Y
L
Q
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation