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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RARS
Full Name:
Arginyl-tRNA synthetase, cytoplasmic
Alias:
Arginine tRNA ligase 1, cytoplasmic; Arginine-tRNA ligase; Arginine--tRNA ligase; Arginyl-tRNA synthetase; ArgRS; DALRD1; SYR; SYRC
Type:
EC 6.1.1.19; Ligase
Mass (Da):
75379
Number AA:
660
UniProt ID:
P54136
International Prot ID:
IPI00004860
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005634
GO:0005625
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004814
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006420
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
D
V
L
V
S
E
C
S
A
R
L
L
Q
Q
E
Site 2
S21
Q
Q
E
E
E
I
K
S
L
T
A
E
I
D
R
Site 3
S38
N
C
G
C
L
G
A
S
P
N
L
E
Q
L
Q
Site 4
Y53
E
E
N
L
K
L
K
Y
R
L
N
I
L
R
K
Site 5
S61
R
L
N
I
L
R
K
S
L
Q
A
E
R
N
K
Site 6
Y92
G
H
A
I
K
A
A
Y
P
D
L
E
N
P
P
Site 7
T103
E
N
P
P
L
L
V
T
P
S
Q
Q
A
K
F
Site 8
S105
P
P
L
L
V
T
P
S
Q
Q
A
K
F
G
D
Site 9
Y113
Q
Q
A
K
F
G
D
Y
Q
C
N
S
A
M
G
Site 10
T127
G
I
S
Q
M
L
K
T
K
E
Q
K
V
N
P
Site 11
S172
H
L
R
K
D
F
V
S
E
Q
L
T
S
L
L
Site 12
Y230
R
L
F
E
F
A
G
Y
D
V
L
R
L
N
H
Site 13
Y259
L
Q
D
K
F
P
D
Y
L
T
V
S
P
P
I
Site 14
T261
D
K
F
P
D
Y
L
T
V
S
P
P
I
G
D
Site 15
S263
F
P
D
Y
L
T
V
S
P
P
I
G
D
L
Q
Site 16
Y273
I
G
D
L
Q
V
F
Y
K
E
S
K
K
R
F
Site 17
S276
L
Q
V
F
Y
K
E
S
K
K
R
F
D
T
E
Site 18
T282
E
S
K
K
R
F
D
T
E
E
E
F
K
K
R
Site 19
Y291
E
E
F
K
K
R
A
Y
Q
C
V
V
L
L
Q
Site 20
T305
Q
G
K
N
P
D
I
T
K
A
W
K
L
I
C
Site 21
Y323
R
Q
E
L
N
K
I
Y
D
A
L
D
V
S
L
Site 22
S329
I
Y
D
A
L
D
V
S
L
I
E
R
G
E
S
Site 23
S336
S
L
I
E
R
G
E
S
F
Y
Q
D
R
M
N
Site 24
Y338
I
E
R
G
E
S
F
Y
Q
D
R
M
N
D
I
Site 25
S378
I
P
L
T
I
V
K
S
D
G
G
Y
T
Y
D
Site 26
Y382
I
V
K
S
D
G
G
Y
T
Y
D
T
S
D
L
Site 27
Y384
K
S
D
G
G
Y
T
Y
D
T
S
D
L
A
A
Site 28
T386
D
G
G
Y
T
Y
D
T
S
D
L
A
A
I
K
Site 29
S387
G
G
Y
T
Y
D
T
S
D
L
A
A
I
K
Q
Site 30
Y406
E
K
A
D
M
I
I
Y
V
V
D
N
G
Q
S
Site 31
T454
E
D
K
K
K
F
K
T
R
S
G
E
T
V
R
Site 32
S456
K
K
K
F
K
T
R
S
G
E
T
V
R
L
M
Site 33
T459
F
K
T
R
S
G
E
T
V
R
L
M
D
L
L
Site 34
S473
L
G
E
G
L
K
R
S
M
D
K
L
K
E
K
Site 35
T487
K
E
R
D
K
V
L
T
A
E
E
L
N
A
A
Site 36
Y505
V
A
Y
G
C
I
K
Y
A
D
L
S
H
N
R
Site 37
Y516
S
H
N
R
L
N
D
Y
I
F
S
F
D
K
M
Site 38
S519
R
L
N
D
Y
I
F
S
F
D
K
M
L
D
D
Site 39
T530
M
L
D
D
R
G
N
T
A
A
Y
L
L
Y
A
Site 40
Y536
N
T
A
A
Y
L
L
Y
A
F
T
R
I
R
S
Site 41
T562
L
Q
K
A
A
R
E
T
K
I
L
L
D
H
E
Site 42
Y616
T
E
F
Y
D
S
C
Y
C
V
E
K
D
R
Q
Site 43
T624
C
V
E
K
D
R
Q
T
G
K
I
L
K
V
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation