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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC5A3
Full Name:
Sodium/myo-inositol cotransporter
Alias:
Na(+)/myo-inositol cotransporter; SC5A3; SL53; SMIT; Sodium/myo-inositol cotransporter; Solute carrier family 5 (sodium/myo-inositol cotransporter) member 3
Type:
Transporter
Mass (Da):
79694
Number AA:
718
UniProt ID:
P53794
International Prot ID:
IPI00296311
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005367
GO:0031402
PhosphoSite+
KinaseNET
Biological Process:
GO:0006814
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
D
I
A
I
V
A
L
Y
F
I
L
V
M
C
I
Site 2
S31
G
F
F
A
M
W
K
S
N
R
S
T
V
S
G
Site 3
S34
A
M
W
K
S
N
R
S
T
V
S
G
Y
F
L
Site 4
T35
M
W
K
S
N
R
S
T
V
S
G
Y
F
L
A
Site 5
S37
K
S
N
R
S
T
V
S
G
Y
F
L
A
G
R
Site 6
Y39
N
R
S
T
V
S
G
Y
F
L
A
G
R
S
M
Site 7
T108
Y
I
R
S
G
V
Y
T
M
P
E
Y
L
S
K
Site 8
Y112
G
V
Y
T
M
P
E
Y
L
S
K
R
F
G
G
Site 9
Y217
F
E
E
V
K
R
R
Y
M
L
A
S
P
D
V
Site 10
S221
K
R
R
Y
M
L
A
S
P
D
V
T
S
I
L
Site 11
T230
D
V
T
S
I
L
L
T
Y
N
L
S
N
T
N
Site 12
T236
L
T
Y
N
L
S
N
T
N
S
C
N
V
S
P
Site 13
S238
Y
N
L
S
N
T
N
S
C
N
V
S
P
K
K
Site 14
S242
N
T
N
S
C
N
V
S
P
K
K
E
A
L
K
Site 15
T255
L
K
M
L
R
N
P
T
D
E
D
V
P
W
P
Site 16
S298
N
I
A
H
A
K
G
S
T
L
M
A
G
F
L
Site 17
T299
I
A
H
A
K
G
S
T
L
M
A
G
F
L
K
Site 18
S320
I
V
V
P
G
M
I
S
R
I
L
F
T
D
D
Site 19
S401
V
Y
K
L
I
R
K
S
A
S
S
R
E
L
M
Site 20
S403
K
L
I
R
K
S
A
S
S
R
E
L
M
I
V
Site 21
Y438
E
M
Q
G
G
Q
M
Y
L
Y
I
Q
E
V
A
Site 22
Y440
Q
G
G
Q
M
Y
L
Y
I
Q
E
V
A
D
Y
Site 23
Y491
R
L
I
L
A
F
A
Y
R
A
P
E
C
D
Q
Site 24
T537
S
L
L
T
P
P
P
T
K
E
Q
I
R
T
T
Site 25
T543
P
T
K
E
Q
I
R
T
T
T
F
W
S
K
K
Site 26
T544
T
K
E
Q
I
R
T
T
T
F
W
S
K
K
N
Site 27
T545
K
E
Q
I
R
T
T
T
F
W
S
K
K
N
L
Site 28
S559
L
V
V
K
E
N
C
S
P
K
E
E
P
Y
Q
Site 29
S571
P
Y
Q
M
Q
E
K
S
I
L
R
C
S
E
N
Site 30
S576
E
K
S
I
L
R
C
S
E
N
N
E
T
I
N
Site 31
S591
H
I
I
P
N
G
K
S
E
D
S
I
K
G
L
Site 32
S594
P
N
G
K
S
E
D
S
I
K
G
L
Q
P
E
Site 33
T608
E
D
V
N
L
L
V
T
C
R
E
E
G
N
P
Site 34
S618
E
E
G
N
P
V
A
S
L
G
H
S
E
A
E
Site 35
S622
P
V
A
S
L
G
H
S
E
A
E
T
P
V
D
Site 36
T626
L
G
H
S
E
A
E
T
P
V
D
A
Y
S
N
Site 37
Y631
A
E
T
P
V
D
A
Y
S
N
G
Q
A
A
L
Site 38
S632
E
T
P
V
D
A
Y
S
N
G
Q
A
A
L
M
Site 39
S666
D
W
F
C
G
F
K
S
K
S
L
S
K
R
S
Site 40
S668
F
C
G
F
K
S
K
S
L
S
K
R
S
L
R
Site 41
S670
G
F
K
S
K
S
L
S
K
R
S
L
R
D
L
Site 42
S673
S
K
S
L
S
K
R
S
L
R
D
L
M
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation