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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COPB1
Full Name:
Coatomer subunit beta
Alias:
Beta-coat protein; Beta-COP; COPB
Type:
Vesicle protein
Mass (Da):
107142
Number AA:
953
UniProt ID:
P53618
International Prot ID:
IPI00295851
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000139
GO:0005737
GO:0005794
Uniprot
OncoNet
Molecular Function:
GO:0005198
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006886
GO:0006890
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
A
A
E
N
V
C
Y
Site 2
S18
L
I
N
V
P
M
D
S
E
P
P
S
E
I
S
Site 3
S22
P
M
D
S
E
P
P
S
E
I
S
L
K
N
D
Site 4
S25
S
E
P
P
S
E
I
S
L
K
N
D
L
E
K
Site 5
S37
L
E
K
G
D
V
K
S
K
T
E
A
L
K
K
Site 6
T39
K
G
D
V
K
S
K
T
E
A
L
K
K
V
I
Site 7
T61
K
L
P
G
L
L
M
T
I
I
R
F
V
L
P
Site 8
T88
F
W
E
I
V
P
K
T
T
P
D
G
R
L
L
Site 9
T89
W
E
I
V
P
K
T
T
P
D
G
R
L
L
H
Site 10
Y105
M
I
L
V
C
D
A
Y
R
K
D
L
Q
H
P
Site 11
S119
P
N
E
F
I
R
G
S
T
L
R
F
L
C
K
Site 12
S149
A
C
L
E
H
R
H
S
Y
V
R
R
N
A
V
Site 13
Y150
C
L
E
H
R
H
S
Y
V
R
R
N
A
V
L
Site 14
Y160
R
N
A
V
L
A
I
Y
T
I
Y
R
N
F
E
Site 15
T161
N
A
V
L
A
I
Y
T
I
Y
R
N
F
E
H
Site 16
Y208
D
Q
D
R
A
L
D
Y
L
S
T
C
I
D
Q
Site 17
S210
D
R
A
L
D
Y
L
S
T
C
I
D
Q
V
Q
Site 18
S240
K
V
C
H
A
N
P
S
E
R
A
R
F
I
R
Site 19
S257
Y
N
L
L
Q
S
S
S
P
A
V
K
Y
E
A
Site 20
T267
V
K
Y
E
A
A
G
T
L
V
T
L
S
S
A
Site 21
T270
E
A
A
G
T
L
V
T
L
S
S
A
P
T
A
Site 22
T276
V
T
L
S
S
A
P
T
A
I
K
A
A
A
Q
Site 23
Y285
I
K
A
A
A
Q
C
Y
I
D
L
I
I
K
E
Site 24
T331
D
I
L
R
V
L
S
T
P
D
L
E
V
R
K
Site 25
T340
D
L
E
V
R
K
K
T
L
Q
L
A
L
D
L
Site 26
T367
L
K
K
E
V
I
K
T
N
N
V
S
E
H
E
Site 27
T376
N
V
S
E
H
E
D
T
D
K
Y
R
Q
L
L
Site 28
Y379
E
H
E
D
T
D
K
Y
R
Q
L
L
V
R
T
Site 29
T386
Y
R
Q
L
L
V
R
T
L
H
S
C
S
V
R
Site 30
S391
V
R
T
L
H
S
C
S
V
R
F
P
D
M
A
Site 31
S451
E
V
F
H
A
I
K
S
V
K
I
Y
R
G
A
Site 32
Y455
A
I
K
S
V
K
I
Y
R
G
A
L
W
I
L
Site 33
S467
W
I
L
G
E
Y
C
S
T
K
E
D
I
Q
S
Site 34
T468
I
L
G
E
Y
C
S
T
K
E
D
I
Q
S
V
Site 35
S474
S
T
K
E
D
I
Q
S
V
M
T
E
I
R
R
Site 36
S491
G
E
I
P
I
V
E
S
E
I
K
K
E
A
G
Site 37
T507
L
K
P
E
E
E
I
T
V
G
P
V
Q
K
L
Site 38
T520
K
L
V
T
E
M
G
T
Y
A
T
Q
S
A
L
Site 39
Y521
L
V
T
E
M
G
T
Y
A
T
Q
S
A
L
S
Site 40
T523
T
E
M
G
T
Y
A
T
Q
S
A
L
S
S
S
Site 41
S525
M
G
T
Y
A
T
Q
S
A
L
S
S
S
R
P
Site 42
S528
Y
A
T
Q
S
A
L
S
S
S
R
P
T
K
K
Site 43
S529
A
T
Q
S
A
L
S
S
S
R
P
T
K
K
E
Site 44
T533
A
L
S
S
S
R
P
T
K
K
E
E
D
R
P
Site 45
S580
Q
E
K
K
K
Q
N
S
F
V
A
E
A
M
L
Site 46
S598
T
I
L
H
L
G
K
S
S
L
P
K
K
P
I
Site 47
S599
I
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Site 48
T606
S
L
P
K
K
P
I
T
D
D
D
V
D
R
I
Site 49
S638
F
N
K
E
C
R
Q
S
L
S
H
M
L
S
A
Site 50
S640
K
E
C
R
Q
S
L
S
H
M
L
S
A
K
L
Site 51
S644
Q
S
L
S
H
M
L
S
A
K
L
E
E
E
K
Site 52
S653
K
L
E
E
E
K
L
S
Q
K
K
E
S
E
K
Site 53
T664
E
S
E
K
R
N
V
T
V
Q
P
D
D
P
I
Site 54
S672
V
Q
P
D
D
P
I
S
F
M
Q
L
T
A
K
Site 55
T677
P
I
S
F
M
Q
L
T
A
K
N
E
M
N
C
Site 56
S692
K
E
D
Q
F
Q
L
S
L
L
A
A
M
G
N
Site 57
S711
E
A
A
D
P
L
A
S
K
L
N
K
V
T
Q
Site 58
Y731
D
P
V
Y
A
E
A
Y
V
H
V
N
Q
Y
D
Site 59
T752
V
V
N
Q
T
S
D
T
L
Q
N
C
T
L
E
Site 60
S773
L
K
L
V
E
K
P
S
P
L
T
L
A
P
H
Site 61
T776
V
E
K
P
S
P
L
T
L
A
P
H
D
F
A
Site 62
S808
G
N
I
V
Y
D
V
S
G
A
A
S
D
R
N
Site 63
T857
E
N
K
V
T
V
N
T
N
M
V
D
L
N
D
Site 64
Y865
N
M
V
D
L
N
D
Y
L
Q
H
I
L
K
S
Site 65
T879
S
T
N
M
K
C
L
T
P
E
K
A
L
S
G
Site 66
T924
Q
G
P
D
A
A
V
T
G
H
I
R
I
R
A
Site 67
S933
H
I
R
I
R
A
K
S
Q
G
M
A
L
S
L
Site 68
S939
K
S
Q
G
M
A
L
S
L
G
D
K
I
N
L
Site 69
S947
L
G
D
K
I
N
L
S
Q
K
K
T
S
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation