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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RBM5
Full Name:
RNA-binding protein 5
Alias:
G15; H37; LUCA15; RMB5; RNA binding motif protein 5
Type:
RNA binding protein
Mass (Da):
92154
Number AA:
815
UniProt ID:
P52756
International Prot ID:
IPI00005036
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003729
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0008285
GO:0043065
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
G
S
D
K
R
V
S
R
T
E
R
S
G
R
Site 2
T10
S
D
K
R
V
S
R
T
E
R
S
G
R
Y
G
Site 3
S13
R
V
S
R
T
E
R
S
G
R
Y
G
S
I
I
Site 4
S18
E
R
S
G
R
Y
G
S
I
I
D
R
D
D
R
Site 5
S30
D
D
R
D
E
R
E
S
R
S
R
R
R
D
S
Site 6
S32
R
D
E
R
E
S
R
S
R
R
R
D
S
D
Y
Site 7
S37
S
R
S
R
R
R
D
S
D
Y
K
R
S
S
D
Site 8
Y39
S
R
R
R
D
S
D
Y
K
R
S
S
D
D
R
Site 9
S43
D
S
D
Y
K
R
S
S
D
D
R
R
G
D
R
Site 10
Y51
D
D
R
R
G
D
R
Y
D
D
Y
R
D
Y
D
Site 11
Y54
R
G
D
R
Y
D
D
Y
R
D
Y
D
S
P
E
Site 12
Y57
R
Y
D
D
Y
R
D
Y
D
S
P
E
R
E
R
Site 13
S59
D
D
Y
R
D
Y
D
S
P
E
R
E
R
E
R
Site 14
S69
R
E
R
E
R
R
N
S
D
R
S
E
D
G
Y
Site 15
S72
E
R
R
N
S
D
R
S
E
D
G
Y
H
S
D
Site 16
Y76
S
D
R
S
E
D
G
Y
H
S
D
G
D
Y
G
Site 17
S78
R
S
E
D
G
Y
H
S
D
G
D
Y
G
E
H
Site 18
Y82
G
Y
H
S
D
G
D
Y
G
E
H
D
Y
R
H
Site 19
Y87
G
D
Y
G
E
H
D
Y
R
H
D
I
S
D
E
Site 20
S92
H
D
Y
R
H
D
I
S
D
E
R
E
S
K
T
Site 21
S97
D
I
S
D
E
R
E
S
K
T
I
M
L
R
G
Site 22
T110
R
G
L
P
I
T
I
T
E
S
D
I
R
E
M
Site 23
S112
L
P
I
T
I
T
E
S
D
I
R
E
M
M
E
Site 24
S120
D
I
R
E
M
M
E
S
F
E
G
P
Q
P
A
Site 25
T136
V
R
L
M
K
R
K
T
G
V
S
R
G
F
A
Site 26
S139
M
K
R
K
T
G
V
S
R
G
F
A
F
V
E
Site 27
Y175
G
K
H
I
A
M
H
Y
S
N
P
R
P
K
F
Site 28
S211
C
G
A
D
K
F
D
S
E
Q
E
V
P
P
G
Site 29
T219
E
Q
E
V
P
P
G
T
T
E
S
V
Q
S
V
Site 30
S222
V
P
P
G
T
T
E
S
V
Q
S
V
D
Y
Y
Site 31
S225
G
T
T
E
S
V
Q
S
V
D
Y
Y
C
D
T
Site 32
T242
L
R
N
I
A
P
H
T
V
V
D
S
I
M
T
Site 33
T249
T
V
V
D
S
I
M
T
A
L
S
P
Y
A
S
Site 34
S252
D
S
I
M
T
A
L
S
P
Y
A
S
L
A
V
Site 35
Y254
I
M
T
A
L
S
P
Y
A
S
L
A
V
N
N
Site 36
S256
T
A
L
S
P
Y
A
S
L
A
V
N
N
I
R
Site 37
T270
R
L
I
K
D
K
Q
T
Q
Q
N
R
G
F
A
Site 38
T307
P
L
K
I
D
G
K
T
I
G
V
D
F
A
K
Site 39
S323
A
R
K
D
L
V
L
S
D
G
N
R
V
S
A
Site 40
S329
L
S
D
G
N
R
V
S
A
F
S
V
A
S
T
Site 41
S344
A
I
A
A
A
Q
W
S
S
T
Q
S
Q
S
G
Site 42
T346
A
A
A
Q
W
S
S
T
Q
S
Q
S
G
E
G
Site 43
S348
A
Q
W
S
S
T
Q
S
Q
S
G
E
G
G
S
Site 44
S350
W
S
S
T
Q
S
Q
S
G
E
G
G
S
V
D
Site 45
S355
S
Q
S
G
E
G
G
S
V
D
Y
S
Y
L
Q
Site 46
Y358
G
E
G
G
S
V
D
Y
S
Y
L
Q
P
G
Q
Site 47
S359
E
G
G
S
V
D
Y
S
Y
L
Q
P
G
Q
D
Site 48
Y360
G
G
S
V
D
Y
S
Y
L
Q
P
G
Q
D
G
Site 49
Y368
L
Q
P
G
Q
D
G
Y
A
Q
Y
A
Q
Y
S
Site 50
Y371
G
Q
D
G
Y
A
Q
Y
A
Q
Y
S
Q
D
Y
Site 51
Y378
Y
A
Q
Y
S
Q
D
Y
Q
Q
F
Y
Q
Q
Q
Site 52
Y382
S
Q
D
Y
Q
Q
F
Y
Q
Q
Q
A
G
G
L
Site 53
S391
Q
Q
A
G
G
L
E
S
D
A
S
S
A
S
G
Site 54
S394
G
G
L
E
S
D
A
S
S
A
S
G
T
A
V
Site 55
S395
G
L
E
S
D
A
S
S
A
S
G
T
A
V
T
Site 56
T399
D
A
S
S
A
S
G
T
A
V
T
T
T
S
A
Site 57
S410
T
T
S
A
A
V
V
S
Q
S
P
Q
L
Y
N
Site 58
S412
S
A
A
V
V
S
Q
S
P
Q
L
Y
N
Q
T
Site 59
Y416
V
S
Q
S
P
Q
L
Y
N
Q
T
S
N
P
P
Site 60
T419
S
P
Q
L
Y
N
Q
T
S
N
P
P
G
S
P
Site 61
S420
P
Q
L
Y
N
Q
T
S
N
P
P
G
S
P
T
Site 62
S425
Q
T
S
N
P
P
G
S
P
T
E
E
A
Q
P
Site 63
T427
S
N
P
P
G
S
P
T
E
E
A
Q
P
S
T
Site 64
S433
P
T
E
E
A
Q
P
S
T
S
T
S
T
Q
A
Site 65
S437
A
Q
P
S
T
S
T
S
T
Q
A
P
A
A
S
Site 66
T438
Q
P
S
T
S
T
S
T
Q
A
P
A
A
S
P
Site 67
S444
S
T
Q
A
P
A
A
S
P
T
G
V
V
P
G
Site 68
T452
P
T
G
V
V
P
G
T
K
Y
A
V
P
D
T
Site 69
Y454
G
V
V
P
G
T
K
Y
A
V
P
D
T
S
T
Site 70
Y462
A
V
P
D
T
S
T
Y
Q
Y
D
E
S
S
G
Site 71
Y464
P
D
T
S
T
Y
Q
Y
D
E
S
S
G
Y
Y
Site 72
Y470
Q
Y
D
E
S
S
G
Y
Y
Y
D
P
T
T
G
Site 73
Y471
Y
D
E
S
S
G
Y
Y
Y
D
P
T
T
G
L
Site 74
Y472
D
E
S
S
G
Y
Y
Y
D
P
T
T
G
L
Y
Site 75
T475
S
G
Y
Y
Y
D
P
T
T
G
L
Y
Y
D
P
Site 76
Y479
Y
D
P
T
T
G
L
Y
Y
D
P
N
S
Q
Y
Site 77
Y480
D
P
T
T
G
L
Y
Y
D
P
N
S
Q
Y
Y
Site 78
Y486
Y
Y
D
P
N
S
Q
Y
Y
Y
N
S
L
T
Q
Site 79
Y487
Y
D
P
N
S
Q
Y
Y
Y
N
S
L
T
Q
Q
Site 80
Y488
D
P
N
S
Q
Y
Y
Y
N
S
L
T
Q
Q
Y
Site 81
Y495
Y
N
S
L
T
Q
Q
Y
L
Y
W
D
G
E
K
Site 82
Y497
S
L
T
Q
Q
Y
L
Y
W
D
G
E
K
E
T
Site 83
Y505
W
D
G
E
K
E
T
Y
V
P
A
A
E
S
S
Site 84
S511
T
Y
V
P
A
A
E
S
S
S
H
Q
Q
S
G
Site 85
S513
V
P
A
A
E
S
S
S
H
Q
Q
S
G
L
P
Site 86
S517
E
S
S
S
H
Q
Q
S
G
L
P
P
A
K
E
Site 87
S534
E
K
K
E
K
P
K
S
K
T
A
Q
Q
I
A
Site 88
S550
D
M
E
R
W
A
K
S
L
N
K
Q
K
E
N
Site 89
S561
Q
K
E
N
F
K
N
S
F
Q
P
V
N
S
L
Site 90
S567
N
S
F
Q
P
V
N
S
L
R
E
E
E
R
R
Site 91
S576
R
E
E
E
R
R
E
S
A
A
A
D
A
G
F
Site 92
S621
R
G
L
V
A
A
Y
S
G
D
S
D
N
E
E
Site 93
S624
V
A
A
Y
S
G
D
S
D
N
E
E
E
L
V
Site 94
S636
E
L
V
E
R
L
E
S
E
E
E
K
L
A
D
Site 95
S669
L
V
R
H
Q
Q
L
S
D
L
H
K
Q
N
M
Site 96
Y679
H
K
Q
N
M
D
I
Y
R
R
S
R
L
S
E
Site 97
S682
N
M
D
I
Y
R
R
S
R
L
S
E
Q
E
L
Site 98
S685
I
Y
R
R
S
R
L
S
E
Q
E
L
E
A
L
Site 99
Y701
L
R
E
R
E
M
K
Y
R
D
R
A
A
E
R
Site 100
Y712
A
A
E
R
R
E
K
Y
G
I
P
E
P
P
E
Site 101
T730
K
K
Q
F
D
A
G
T
V
N
Y
E
Q
P
T
Site 102
Y733
F
D
A
G
T
V
N
Y
E
Q
P
T
K
D
G
Site 103
S744
T
K
D
G
I
D
H
S
N
I
G
N
K
M
L
Site 104
S760
A
M
G
W
R
E
G
S
G
L
G
R
K
C
Q
Site 105
T770
G
R
K
C
Q
G
I
T
A
P
I
E
A
Q
V
Site 106
S789
A
G
L
G
A
K
G
S
A
Y
G
L
S
G
A
Site 107
Y791
L
G
A
K
G
S
A
Y
G
L
S
G
A
D
S
Site 108
S794
K
G
S
A
Y
G
L
S
G
A
D
S
Y
K
D
Site 109
S798
Y
G
L
S
G
A
D
S
Y
K
D
A
V
R
K
Site 110
Y799
G
L
S
G
A
D
S
Y
K
D
A
V
R
K
A
Site 111
T812
K
A
M
F
A
R
F
T
E
M
E
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation