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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF133
Full Name:
Zinc finger protein 133
Alias:
PHZ-13; PHZ-66; ZN133; ZNF150
Type:
Mass (Da):
73390
Number AA:
UniProt ID:
P52736
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
R
D
V
A
V
D
F
T
Q
D
E
W
R
L
L
Site 2
S19
Q
D
E
W
R
L
L
S
P
A
Q
R
T
L
Y
Site 3
Y26
S
P
A
Q
R
T
L
Y
R
E
V
M
L
E
N
Site 4
Y34
R
E
V
M
L
E
N
Y
S
N
L
V
S
L
G
Site 5
S39
E
N
Y
S
N
L
V
S
L
G
I
S
F
S
K
Site 6
S67
W
R
E
E
K
K
C
S
P
A
T
C
P
A
D
Site 7
Y80
A
D
P
E
P
E
L
Y
L
D
P
F
C
P
P
Site 8
S90
P
F
C
P
P
G
F
S
S
Q
K
F
P
M
Q
Site 9
S140
A
S
E
G
R
P
W
S
D
Q
A
E
G
P
E
Site 10
T162
F
G
R
T
K
K
R
T
L
G
A
F
S
R
P
Site 11
S167
K
R
T
L
G
A
F
S
R
P
P
Q
R
Q
P
Site 12
S176
P
P
Q
R
Q
P
V
S
S
R
N
G
L
R
G
Site 13
S177
P
Q
R
Q
P
V
S
S
R
N
G
L
R
G
V
Site 14
S189
R
G
V
E
L
E
A
S
P
A
Q
S
G
N
P
Site 15
S193
L
E
A
S
P
A
Q
S
G
N
P
E
E
T
D
Site 16
S231
S
K
M
T
N
L
L
S
H
Q
R
I
H
S
G
Site 17
S237
L
S
H
Q
R
I
H
S
G
E
K
P
Y
V
C
Site 18
Y242
I
H
S
G
E
K
P
Y
V
C
G
V
C
E
K
Site 19
S252
G
V
C
E
K
G
F
S
L
K
K
S
L
A
R
Site 20
S256
K
G
F
S
L
K
K
S
L
A
R
H
Q
K
A
Site 21
S283
G
R
G
F
N
R
K
S
T
L
I
I
H
E
R
Site 22
T284
R
G
F
N
R
K
S
T
L
I
I
H
E
R
T
Site 23
Y298
T
H
S
G
E
K
P
Y
M
C
S
E
C
G
R
Site 24
S301
G
E
K
P
Y
M
C
S
E
C
G
R
G
F
S
Site 25
S308
S
E
C
G
R
G
F
S
Q
K
S
N
L
I
I
Site 26
S311
G
R
G
F
S
Q
K
S
N
L
I
I
H
Q
R
Site 27
Y326
T
H
S
G
E
K
P
Y
V
C
R
E
C
G
K
Site 28
S336
R
E
C
G
K
G
F
S
Q
K
S
A
V
V
R
Site 29
S339
G
K
G
F
S
Q
K
S
A
V
V
R
H
Q
R
Site 30
T353
R
T
H
L
E
E
K
T
I
V
C
S
D
C
G
Site 31
S364
S
D
C
G
L
G
F
S
D
R
S
N
L
I
S
Site 32
S367
G
L
G
F
S
D
R
S
N
L
I
S
H
Q
R
Site 33
S371
S
D
R
S
N
L
I
S
H
Q
R
T
H
S
G
Site 34
T375
N
L
I
S
H
Q
R
T
H
S
G
E
K
P
Y
Site 35
S377
I
S
H
Q
R
T
H
S
G
E
K
P
Y
A
C
Site 36
Y382
T
H
S
G
E
K
P
Y
A
C
K
E
C
G
R
Site 37
T395
G
R
C
F
R
Q
R
T
T
L
V
N
H
Q
R
Site 38
T396
R
C
F
R
Q
R
T
T
L
V
N
H
Q
R
T
Site 39
Y410
T
H
S
K
E
K
P
Y
V
C
G
V
C
G
H
Site 40
S420
G
V
C
G
H
S
F
S
Q
N
S
T
L
I
S
Site 41
S423
G
H
S
F
S
Q
N
S
T
L
I
S
H
R
R
Site 42
T424
H
S
F
S
Q
N
S
T
L
I
S
H
R
R
T
Site 43
S427
S
Q
N
S
T
L
I
S
H
R
R
T
H
T
G
Site 44
T431
T
L
I
S
H
R
R
T
H
T
G
E
K
P
Y
Site 45
T433
I
S
H
R
R
T
H
T
G
E
K
P
Y
V
C
Site 46
Y438
T
H
T
G
E
K
P
Y
V
C
G
V
C
G
R
Site 47
S448
G
V
C
G
R
G
F
S
L
K
S
H
L
N
R
Site 48
S451
G
R
G
F
S
L
K
S
H
L
N
R
H
Q
N
Site 49
S476
K
D
C
G
R
G
F
S
Q
Q
S
N
L
I
R
Site 50
S479
G
R
G
F
S
Q
Q
S
N
L
I
R
H
Q
R
Site 51
S489
I
R
H
Q
R
T
H
S
G
E
K
P
M
V
C
Site 52
S504
G
E
C
G
R
G
F
S
Q
K
S
N
L
V
A
Site 53
S507
G
R
G
F
S
Q
K
S
N
L
V
A
H
Q
R
Site 54
S517
V
A
H
Q
R
T
H
S
G
E
R
P
Y
V
C
Site 55
Y522
T
H
S
G
E
R
P
Y
V
C
R
E
C
G
R
Site 56
S532
R
E
C
G
R
G
F
S
H
Q
A
G
L
I
R
Site 57
Y550
K
H
S
R
E
K
P
Y
M
C
R
Q
C
G
L
Site 58
S563
G
L
G
F
G
N
K
S
A
L
I
T
H
K
R
Site 59
T567
G
N
K
S
A
L
I
T
H
K
R
A
H
S
E
Site 60
S573
I
T
H
K
R
A
H
S
E
E
K
P
C
V
C
Site 61
S591
G
Q
G
F
L
Q
K
S
H
L
T
L
H
Q
M
Site 62
T594
F
L
Q
K
S
H
L
T
L
H
Q
M
T
H
T
Site 63
Y606
T
H
T
G
E
K
P
Y
V
C
K
T
C
G
R
Site 64
T610
E
K
P
Y
V
C
K
T
C
G
R
G
F
S
L
Site 65
S616
K
T
C
G
R
G
F
S
L
K
S
H
L
S
R
Site 66
S619
G
R
G
F
S
L
K
S
H
L
S
R
H
R
K
Site 67
S622
F
S
L
K
S
H
L
S
R
H
R
K
T
T
S
Site 68
T627
H
L
S
R
H
R
K
T
T
S
V
H
H
R
L
Site 69
T628
L
S
R
H
R
K
T
T
S
V
H
H
R
L
P
Site 70
S629
S
R
H
R
K
T
T
S
V
H
H
R
L
P
V
Site 71
S648
E
P
C
A
G
Q
P
S
D
S
L
Y
S
L
_
Site 72
S650
C
A
G
Q
P
S
D
S
L
Y
S
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation