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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC7A2
Full Name:
Low affinity cationic amino acid transporter 2
Alias:
ATRC2; CAT2; CAT-2; CTR2; HCAT2; Low-affinity cationic amino acid transporter-2; Solute carrier family 7 (cationic amino acid transporter, y+ system) member 2; Solute carrier family 7 member 2
Type:
Transport protein, facilitator
Mass (Da):
71673
Number AA:
658
UniProt ID:
P52569
International Prot ID:
IPI00003819
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0015174
PhosphoSite+
KinaseNET
Biological Process:
GO:0006865
GO:0006520
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
L
I
R
R
K
I
V
T
L
D
S
L
E
D
T
Site 2
S24
R
K
I
V
T
L
D
S
L
E
D
T
K
L
C
Site 3
T28
T
L
D
S
L
E
D
T
K
L
C
R
C
L
S
Site 4
T96
F
G
A
R
V
P
K
T
G
S
A
Y
L
Y
T
Site 5
Y102
K
T
G
S
A
Y
L
Y
T
Y
V
T
V
G
E
Site 6
S135
S
S
V
A
R
A
W
S
G
T
F
D
E
L
L
Site 7
T137
V
A
R
A
W
S
G
T
F
D
E
L
L
S
K
Site 8
S143
G
T
F
D
E
L
L
S
K
Q
I
G
Q
F
L
Site 9
Y153
I
G
Q
F
L
R
T
Y
F
R
M
N
Y
T
G
Site 10
Y158
R
T
Y
F
R
M
N
Y
T
G
L
A
E
Y
P
Site 11
S231
F
L
K
N
I
S
A
S
A
R
E
P
P
S
E
Site 12
S237
A
S
A
R
E
P
P
S
E
N
G
T
S
I
Y
Site 13
T241
E
P
P
S
E
N
G
T
S
I
Y
G
A
G
G
Site 14
S242
P
P
S
E
N
G
T
S
I
Y
G
A
G
G
F
Site 15
Y244
S
E
N
G
T
S
I
Y
G
A
G
G
F
M
P
Site 16
Y303
L
L
V
C
F
M
A
Y
F
G
V
S
A
A
L
Site 17
S307
F
M
A
Y
F
G
V
S
A
A
L
T
L
M
M
Site 18
Y317
L
T
L
M
M
P
Y
Y
L
L
D
E
K
S
P
Site 19
S323
Y
Y
L
L
D
E
K
S
P
L
P
V
A
F
E
Site 20
S382
K
C
L
A
Q
I
N
S
K
T
K
T
P
I
I
Site 21
T386
Q
I
N
S
K
T
K
T
P
I
I
A
T
L
S
Site 22
S439
L
R
Y
Q
P
G
L
S
Y
D
Q
P
K
C
S
Site 23
Y440
R
Y
Q
P
G
L
S
Y
D
Q
P
K
C
S
P
Site 24
S446
S
Y
D
Q
P
K
C
S
P
E
K
D
G
L
G
Site 25
S454
P
E
K
D
G
L
G
S
S
P
R
V
T
S
K
Site 26
S455
E
K
D
G
L
G
S
S
P
R
V
T
S
K
S
Site 27
T459
L
G
S
S
P
R
V
T
S
K
S
E
S
Q
V
Site 28
S460
G
S
S
P
R
V
T
S
K
S
E
S
Q
V
T
Site 29
S462
S
P
R
V
T
S
K
S
E
S
Q
V
T
M
L
Site 30
S464
R
V
T
S
K
S
E
S
Q
V
T
M
L
Q
R
Site 31
T467
S
K
S
E
S
Q
V
T
M
L
Q
R
Q
G
F
Site 32
S483
M
R
T
L
F
C
P
S
L
L
P
T
Q
Q
S
Site 33
S606
F
S
Y
G
I
R
H
S
L
E
G
H
L
R
D
Site 34
Y621
E
N
N
E
E
D
A
Y
P
D
N
V
H
A
A
Site 35
S646
D
H
H
P
R
N
L
S
S
P
F
I
F
H
E
Site 36
S647
H
H
P
R
N
L
S
S
P
F
I
F
H
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation