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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLXNA3
Full Name:
Plexin-A3
Alias:
HSSEXGENE; Plexin 4; Plexin A3; Plexin-4; PLXA3; PLXN3; PLXN4; Semaphorin receptor SEX; SEX; Sex chromosome X transmembrane protein of HGF receptor family 3; XAP-6
Type:
Intracellular, Membrane, Integral membrane protein
Mass (Da):
207703
Number AA:
1871
UniProt ID:
P51805
International Prot ID:
IPI00020884
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005622
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y289
C
S
W
R
G
V
E
Y
R
L
V
Q
S
A
H
Site 2
T606
L
Q
E
L
R
A
L
T
R
G
H
G
A
T
R
Site 3
T614
R
G
H
G
A
T
R
T
V
R
L
Q
L
L
S
Site 4
S958
T
R
L
T
I
S
G
S
S
L
D
A
G
S
R
Site 5
S964
G
S
S
L
D
A
G
S
R
V
T
V
T
V
R
Site 6
Y1122
N
R
S
S
F
T
Y
Y
P
D
P
S
F
E
P
Site 7
T1246
L
V
A
Y
K
R
K
T
Q
D
A
D
R
T
L
Site 8
T1252
K
T
Q
D
A
D
R
T
L
K
R
L
Q
L
Q
Site 9
T1322
P
V
L
K
E
L
D
T
P
P
N
V
E
K
A
Site 10
S1355
H
T
L
E
A
Q
S
S
F
S
M
R
D
R
G
Site 11
S1357
L
E
A
Q
S
S
F
S
M
R
D
R
G
T
V
Site 12
Y1378
A
L
Q
S
R
L
D
Y
A
T
G
L
L
K
Q
Site 13
T1380
Q
S
R
L
D
Y
A
T
G
L
L
K
Q
L
L
Site 14
S1397
L
I
E
K
N
L
E
S
K
N
H
P
K
L
L
Site 15
T1408
P
K
L
L
L
R
R
T
E
S
V
A
E
K
M
Site 16
S1410
L
L
L
R
R
T
E
S
V
A
E
K
M
L
T
Site 17
T1456
K
G
P
I
D
A
I
T
G
E
A
R
Y
S
L
Site 18
Y1461
A
I
T
G
E
A
R
Y
S
L
S
E
D
K
L
Site 19
S1462
I
T
G
E
A
R
Y
S
L
S
E
D
K
L
I
Site 20
S1464
G
E
A
R
Y
S
L
S
E
D
K
L
I
R
Q
Site 21
Y1475
L
I
R
Q
Q
I
D
Y
K
T
L
T
L
H
C
Site 22
T1477
R
Q
Q
I
D
Y
K
T
L
T
L
H
C
V
C
Site 23
S1490
V
C
P
E
N
E
G
S
A
Q
V
P
V
K
V
Site 24
T1513
A
K
D
K
L
L
D
T
V
Y
K
G
I
P
Y
Site 25
Y1515
D
K
L
L
D
T
V
Y
K
G
I
P
Y
S
Q
Site 26
S1521
V
Y
K
G
I
P
Y
S
Q
R
P
K
A
E
D
Site 27
T1539
E
W
R
Q
G
R
M
T
R
I
I
L
Q
D
E
Site 28
Y1565
R
L
N
S
L
A
H
Y
Q
V
T
D
G
S
L
Site 29
S1581
A
L
V
P
K
Q
V
S
A
Y
N
M
A
N
S
Site 30
Y1583
V
P
K
Q
V
S
A
Y
N
M
A
N
S
F
T
Site 31
S1588
S
A
Y
N
M
A
N
S
F
T
F
T
R
S
L
Site 32
T1590
Y
N
M
A
N
S
F
T
F
T
R
S
L
S
R
Site 33
T1592
M
A
N
S
F
T
F
T
R
S
L
S
R
Y
E
Site 34
S1594
N
S
F
T
F
T
R
S
L
S
R
Y
E
S
L
Site 35
S1596
F
T
F
T
R
S
L
S
R
Y
E
S
L
L
R
Site 36
Y1598
F
T
R
S
L
S
R
Y
E
S
L
L
R
T
A
Site 37
S1600
R
S
L
S
R
Y
E
S
L
L
R
T
A
S
S
Site 38
T1604
R
Y
E
S
L
L
R
T
A
S
S
P
D
S
L
Site 39
S1606
E
S
L
L
R
T
A
S
S
P
D
S
L
R
S
Site 40
S1607
S
L
L
R
T
A
S
S
P
D
S
L
R
S
R
Site 41
S1610
R
T
A
S
S
P
D
S
L
R
S
R
A
P
M
Site 42
S1613
S
S
P
D
S
L
R
S
R
A
P
M
I
T
P
Site 43
T1619
R
S
R
A
P
M
I
T
P
D
Q
E
T
G
T
Site 44
S1647
H
R
E
G
D
R
G
S
K
M
V
S
E
I
Y
Site 45
S1651
D
R
G
S
K
M
V
S
E
I
Y
L
T
R
L
Site 46
T1664
R
L
L
A
T
K
G
T
L
Q
K
F
V
D
D
Site 47
S1678
D
L
F
E
T
V
F
S
T
A
H
R
G
S
A
Site 48
S1707
Q
A
D
Q
R
Q
I
S
D
P
D
V
R
H
T
Site 49
T1714
S
D
P
D
V
R
H
T
W
K
S
N
C
L
P
Site 50
S1758
V
A
Q
T
F
M
D
S
C
S
T
S
E
H
R
Site 51
S1760
Q
T
F
M
D
S
C
S
T
S
E
H
R
L
G
Site 52
S1762
F
M
D
S
C
S
T
S
E
H
R
L
G
K
D
Site 53
S1770
E
H
R
L
G
K
D
S
P
S
N
K
L
L
Y
Site 54
S1772
R
L
G
K
D
S
P
S
N
K
L
L
Y
A
K
Site 55
Y1777
S
P
S
N
K
L
L
Y
A
K
D
I
P
N
Y
Site 56
Y1784
Y
A
K
D
I
P
N
Y
K
S
W
V
E
R
Y
Site 57
Y1791
Y
K
S
W
V
E
R
Y
Y
R
D
I
A
K
M
Site 58
Y1792
K
S
W
V
E
R
Y
Y
R
D
I
A
K
M
A
Site 59
S1802
I
A
K
M
A
S
I
S
D
Q
D
M
D
A
Y
Site 60
Y1809
S
D
Q
D
M
D
A
Y
L
V
E
Q
S
R
L
Site 61
S1819
E
Q
S
R
L
H
A
S
D
F
S
V
L
S
A
Site 62
S1822
R
L
H
A
S
D
F
S
V
L
S
A
L
N
E
Site 63
Y1831
L
S
A
L
N
E
L
Y
F
Y
V
T
K
Y
R
Site 64
Y1833
A
L
N
E
L
Y
F
Y
V
T
K
Y
R
Q
E
Site 65
Y1837
L
Y
F
Y
V
T
K
Y
R
Q
E
I
L
T
A
Site 66
T1843
K
Y
R
Q
E
I
L
T
A
L
D
R
D
A
S
Site 67
S1850
T
A
L
D
R
D
A
S
C
R
K
H
K
L
R
Site 68
S1865
Q
K
L
E
Q
I
I
S
L
V
S
S
D
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation