KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CLCNKA
Full Name:
Chloride channel protein ClC-Ka
Alias:
Chloride channel Ka; ClC-K1; hClC-Ka
Type:
Mass (Da):
75285
Number AA:
687
UniProt ID:
P51800
International Prot ID:
IPI00020879
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0034707
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0031404
GO:0005247
PhosphoSite+
KinaseNET
Biological Process:
GO:0006821
GO:0007588
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
V
G
L
R
E
G
F
S
G
D
P
V
T
L
Q
Site 2
T17
G
F
S
G
D
P
V
T
L
Q
E
L
W
G
P
Site 3
Y82
V
R
A
H
Q
W
L
Y
R
E
I
G
D
S
H
Site 4
S88
L
Y
R
E
I
G
D
S
H
L
L
R
Y
L
S
Site 5
Y93
G
D
S
H
L
L
R
Y
L
S
W
T
V
Y
P
Site 6
S111
V
S
F
S
S
G
F
S
Q
S
I
T
P
S
S
Site 7
S113
F
S
S
G
F
S
Q
S
I
T
P
S
S
G
G
Site 8
T115
S
G
F
S
Q
S
I
T
P
S
S
G
G
S
G
Site 9
S117
F
S
Q
S
I
T
P
S
S
G
G
S
G
I
P
Site 10
S118
S
Q
S
I
T
P
S
S
G
G
S
G
I
P
E
Site 11
S121
I
T
P
S
S
G
G
S
G
I
P
E
L
K
T
Site 12
T185
A
Y
L
G
R
V
R
T
T
T
I
G
E
P
E
Site 13
T186
Y
L
G
R
V
R
T
T
T
I
G
E
P
E
N
Site 14
T187
L
G
R
V
R
T
T
T
I
G
E
P
E
N
K
Site 15
S195
I
G
E
P
E
N
K
S
K
Q
N
E
M
L
V
Site 16
S229
F
S
I
E
V
M
S
S
H
F
S
V
R
D
Y
Site 17
S232
E
V
M
S
S
H
F
S
V
R
D
Y
W
R
G
Site 18
Y236
S
H
F
S
V
R
D
Y
W
R
G
F
F
A
A
Site 19
S258
R
L
L
A
V
F
N
S
E
Q
E
T
I
T
S
Site 20
T262
V
F
N
S
E
Q
E
T
I
T
S
L
Y
K
T
Site 21
S265
S
E
Q
E
T
I
T
S
L
Y
K
T
S
F
R
Site 22
Y267
Q
E
T
I
T
S
L
Y
K
T
S
F
R
V
D
Site 23
T269
T
I
T
S
L
Y
K
T
S
F
R
V
D
V
P
Site 24
T312
T
F
L
S
F
I
K
T
N
R
Y
S
S
K
L
Site 25
Y315
S
F
I
K
T
N
R
Y
S
S
K
L
L
A
T
Site 26
S316
F
I
K
T
N
R
Y
S
S
K
L
L
A
T
S
Site 27
S317
I
K
T
N
R
Y
S
S
K
L
L
A
T
S
K
Site 28
S353
H
F
L
A
S
R
L
S
M
K
Q
H
L
D
S
Site 29
S374
W
A
L
M
T
Q
N
S
S
P
P
W
P
E
E
Site 30
S375
A
L
M
T
Q
N
S
S
P
P
W
P
E
E
L
Site 31
S514
A
A
N
A
I
A
Q
S
C
Q
P
S
F
Y
D
Site 32
T523
Q
P
S
F
Y
D
G
T
I
I
V
K
K
L
P
Site 33
T562
I
T
T
L
A
K
D
T
P
L
E
E
V
V
K
Site 34
Y579
T
S
T
D
V
T
E
Y
P
L
V
E
S
T
E
Site 35
S609
A
L
Q
A
E
P
P
S
R
A
P
G
H
Q
Q
Site 36
S655
F
K
L
L
N
L
Q
S
L
F
V
T
S
R
G
Site 37
T659
N
L
Q
S
L
F
V
T
S
R
G
R
A
V
G
Site 38
S660
L
Q
S
L
F
V
T
S
R
G
R
A
V
G
C
Site 39
T681
K
K
A
I
S
N
L
T
N
P
P
A
P
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation