PhosphoNET

           
Protein Info 
   
Short Name:  GALK1
Full Name:  Galactokinase
Alias:  EC 2.7.1.6; Galactokinase 1; Galactose kinase; GALK; GK1
Type:  Enzyme - Kinase - metabolite
Mass (Da):  42272
Number AA:  392
UniProt ID:  P51570
International Prot ID:  IPI00019383
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829     Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0004335  GO:0005534 PhosphoSite+ KinaseNET
Biological Process:  GO:0046835  GO:0006012   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y47LIGEHTDYNQGLVLP
Site 2T61PMALELMTVLVGSPR
Site 3S74PRKDGLVSLLTTSEG
Site 4T77DGLVSLLTTSEGADE
Site 5T94RLQFPLPTAQRSLEP
Site 6S98PLPTAQRSLEPGTPR
Site 7T103QRSLEPGTPRWANYV
Site 8Y109GTPRWANYVKGVIQY
Site 9S209DCRSLETSLVPLSDP
Site 10T223PKLAVLITNSNVRHS
Site 11S230TNSNVRHSLASSEYP
Site 12S233NVRHSLASSEYPVRR
Site 13S234VRHSLASSEYPVRRR
Site 14Y236HSLASSEYPVRRRQC
Site 15S254ARALGKESLREVQLE
Site 16S271EAARDLVSKEGFRRA
Site 17Y300AALRRGDYRAFGRLM
Site 18S310FGRLMVESHRSLRDD
Site 19S313LMVESHRSLRDDYEV
Site 20Y318HRSLRDDYEVSCPEL
Site 21S321LRDDYEVSCPELDQL
Site 22T344GVYGSRMTGGGFGGC
Site 23T377EHYGGTATFYLSQAA
Site 24Y379YGGTATFYLSQAADG
Site 25S381GTATFYLSQAADGAK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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