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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF81
Full Name:
Zinc finger protein 81
Alias:
HFZ20
Type:
Mass (Da):
75960
Number AA:
661
UniProt ID:
P51508
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
P
Q
P
G
E
H
G
S
A
C
E
V
S
V
S
Site 2
S20
H
G
S
A
C
E
V
S
V
S
F
E
D
V
T
Site 3
T27
S
V
S
F
E
D
V
T
V
D
F
S
R
E
E
Site 4
S31
E
D
V
T
V
D
F
S
R
E
E
W
Q
Q
L
Site 5
S40
E
E
W
Q
Q
L
D
S
T
Q
R
R
L
Y
Q
Site 6
T41
E
W
Q
Q
L
D
S
T
Q
R
R
L
Y
Q
D
Site 7
Y46
D
S
T
Q
R
R
L
Y
Q
D
V
M
L
E
N
Site 8
Y54
Q
D
V
M
L
E
N
Y
S
H
L
L
S
V
G
Site 9
S59
E
N
Y
S
H
L
L
S
V
G
F
E
V
P
K
Site 10
T81
E
Q
G
E
G
P
W
T
L
E
G
E
A
P
H
Site 11
S90
E
G
E
A
P
H
Q
S
C
S
D
G
K
F
G
Site 12
S92
E
A
P
H
Q
S
C
S
D
G
K
F
G
I
K
Site 13
S101
G
K
F
G
I
K
P
S
Q
R
R
I
S
G
K
Site 14
S106
K
P
S
Q
R
R
I
S
G
K
S
T
F
H
S
Site 15
S109
Q
R
R
I
S
G
K
S
T
F
H
S
E
M
E
Site 16
T110
R
R
I
S
G
K
S
T
F
H
S
E
M
E
G
Site 17
S113
S
G
K
S
T
F
H
S
E
M
E
G
E
D
T
Site 18
T120
S
E
M
E
G
E
D
T
R
D
D
S
L
Y
S
Site 19
S124
G
E
D
T
R
D
D
S
L
Y
S
I
L
E
E
Site 20
Y126
D
T
R
D
D
S
L
Y
S
I
L
E
E
L
W
Site 21
S127
T
R
D
D
S
L
Y
S
I
L
E
E
L
W
Q
Site 22
S151
E
K
H
N
K
L
L
S
R
T
T
F
L
N
K
Site 23
T154
N
K
L
L
S
R
T
T
F
L
N
K
K
I
L
Site 24
Y167
I
L
N
T
E
W
D
Y
E
Y
K
D
F
G
K
Site 25
Y169
N
T
E
W
D
Y
E
Y
K
D
F
G
K
F
V
Site 26
S185
P
S
P
N
L
I
L
S
Q
K
R
P
H
K
R
Site 27
S194
K
R
P
H
K
R
D
S
F
G
K
S
F
K
H
Site 28
S198
K
R
D
S
F
G
K
S
F
K
H
N
L
D
L
Site 29
S211
D
L
H
I
H
N
K
S
N
A
A
K
N
L
D
Site 30
T220
A
A
K
N
L
D
K
T
I
G
H
G
Q
V
F
Site 31
T228
I
G
H
G
Q
V
F
T
Q
N
S
S
Y
S
H
Site 32
T241
S
H
H
E
N
T
H
T
G
V
K
F
C
E
R
Site 33
S256
N
Q
C
G
K
V
L
S
L
K
H
S
L
S
Q
Site 34
S260
K
V
L
S
L
K
H
S
L
S
Q
N
V
K
F
Site 35
S262
L
S
L
K
H
S
L
S
Q
N
V
K
F
P
I
Site 36
T275
P
I
G
E
K
A
N
T
C
T
E
F
G
K
I
Site 37
T284
T
E
F
G
K
I
F
T
Q
R
S
H
F
F
A
Site 38
S287
G
K
I
F
T
Q
R
S
H
F
F
A
P
Q
K
Site 39
T297
F
A
P
Q
K
I
H
T
V
E
K
P
H
E
L
Site 40
S318
F
T
Q
K
P
L
L
S
I
Y
L
R
V
H
R
Site 41
Y320
Q
K
P
L
L
S
I
Y
L
R
V
H
R
D
E
Site 42
Y330
V
H
R
D
E
K
L
Y
I
C
T
K
C
G
K
Site 43
S343
G
K
A
F
I
Q
N
S
E
L
I
M
H
E
K
Site 44
T351
E
L
I
M
H
E
K
T
H
T
R
E
K
P
Y
Site 45
T353
I
M
H
E
K
T
H
T
R
E
K
P
Y
K
C
Site 46
Y358
T
H
T
R
E
K
P
Y
K
C
N
E
C
G
K
Site 47
S366
K
C
N
E
C
G
K
S
F
F
Q
V
S
S
L
Site 48
S372
K
S
F
F
Q
V
S
S
L
L
R
H
Q
T
T
Site 49
T378
S
S
L
L
R
H
Q
T
T
H
T
G
E
K
L
Site 50
S389
G
E
K
L
F
E
C
S
E
C
G
K
G
F
S
Site 51
S396
S
E
C
G
K
G
F
S
L
N
S
A
L
N
I
Site 52
S399
G
K
G
F
S
L
N
S
A
L
N
I
H
Q
K
Site 53
T424
S
E
C
G
K
A
F
T
Q
K
S
T
L
R
M
Site 54
S427
G
K
A
F
T
Q
K
S
T
L
R
M
H
Q
R
Site 55
T428
K
A
F
T
Q
K
S
T
L
R
M
H
Q
R
I
Site 56
T437
R
M
H
Q
R
I
H
T
G
E
R
S
Y
I
C
Site 57
Y442
I
H
T
G
E
R
S
Y
I
C
T
Q
C
G
Q
Site 58
T465
I
A
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 59
Y470
I
H
T
G
E
K
P
Y
E
C
S
D
C
G
K
Site 60
S473
G
E
K
P
Y
E
C
S
D
C
G
K
S
F
P
Site 61
S478
E
C
S
D
C
G
K
S
F
P
S
K
S
Q
L
Site 62
S481
D
C
G
K
S
F
P
S
K
S
Q
L
Q
M
H
Site 63
S483
G
K
S
F
P
S
K
S
Q
L
Q
M
H
K
R
Site 64
T493
Q
M
H
K
R
I
H
T
G
E
K
P
Y
I
C
Site 65
Y498
I
H
T
G
E
K
P
Y
I
C
T
E
C
G
K
Site 66
T508
T
E
C
G
K
A
F
T
N
R
S
N
L
N
T
Site 67
S511
G
K
A
F
T
N
R
S
N
L
N
T
H
Q
K
Site 68
T515
T
N
R
S
N
L
N
T
H
Q
K
S
H
T
G
Site 69
S519
N
L
N
T
H
Q
K
S
H
T
G
E
K
S
Y
Site 70
T521
N
T
H
Q
K
S
H
T
G
E
K
S
Y
I
C
Site 71
Y526
S
H
T
G
E
K
S
Y
I
C
A
E
C
G
K
Site 72
T536
A
E
C
G
K
A
F
T
D
R
S
N
F
N
K
Site 73
S539
G
K
A
F
T
D
R
S
N
F
N
K
H
Q
T
Site 74
T549
N
K
H
Q
T
I
H
T
G
E
K
P
Y
V
C
Site 75
Y554
I
H
T
G
E
K
P
Y
V
C
A
D
C
G
R
Site 76
S567
G
R
A
F
I
Q
K
S
E
L
I
T
H
Q
R
Site 77
T577
I
T
H
Q
R
I
H
T
T
E
K
P
Y
K
C
Site 78
Y582
I
H
T
T
E
K
P
Y
K
C
P
D
C
E
K
Site 79
S590
K
C
P
D
C
E
K
S
F
S
K
K
P
H
L
Site 80
S592
P
D
C
E
K
S
F
S
K
K
P
H
L
K
V
Site 81
T605
K
V
H
Q
R
I
H
T
G
E
K
P
Y
I
C
Site 82
Y610
I
H
T
G
E
K
P
Y
I
C
A
E
C
G
K
Site 83
Y638
I
H
T
G
D
K
P
Y
K
C
S
D
C
G
K
Site 84
T648
S
D
C
G
K
G
F
T
Q
K
S
V
L
S
M
Site 85
S651
G
K
G
F
T
Q
K
S
V
L
S
M
H
R
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation