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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCT4
Full Name:
T-complex protein 1 subunit delta
Alias:
CCTD; SRB; Stimulator of TAR RNA binding; TCP-1-delta; TCPD
Type:
Chaperone protein
Mass (Da):
57924
Number AA:
539
UniProt ID:
P50991
International Prot ID:
IPI00302927
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042470
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
GO:0000074
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
P
E
N
V
A
P
R
S
G
A
T
A
G
A
A
Site 2
Y24
G
G
R
G
K
G
A
Y
Q
D
R
D
K
P
A
Site 3
S36
K
P
A
Q
I
R
F
S
N
I
S
A
A
K
A
Site 4
S51
V
A
D
A
I
R
T
S
L
G
P
K
G
M
D
Site 5
T69
Q
D
G
K
G
D
V
T
I
T
N
D
G
A
T
Site 6
S95
A
R
M
L
V
E
L
S
K
A
Q
D
I
E
A
Site 7
S136
H
P
T
I
I
S
E
S
F
Q
K
A
L
E
K
Site 8
T149
E
K
G
I
E
I
L
T
D
M
S
R
P
V
E
Site 9
S152
I
E
I
L
T
D
M
S
R
P
V
E
L
S
D
Site 10
S158
M
S
R
P
V
E
L
S
D
R
E
T
L
L
N
Site 11
T162
V
E
L
S
D
R
E
T
L
L
N
S
A
T
T
Site 12
S166
D
R
E
T
L
L
N
S
A
T
T
S
L
N
S
Site 13
T168
E
T
L
L
N
S
A
T
T
S
L
N
S
K
V
Site 14
S170
L
L
N
S
A
T
T
S
L
N
S
K
V
V
S
Site 15
S173
S
A
T
T
S
L
N
S
K
V
V
S
Q
Y
S
Site 16
S177
S
L
N
S
K
V
V
S
Q
Y
S
S
L
L
S
Site 17
S180
S
K
V
V
S
Q
Y
S
S
L
L
S
P
M
S
Site 18
S181
K
V
V
S
Q
Y
S
S
L
L
S
P
M
S
V
Site 19
S184
S
Q
Y
S
S
L
L
S
P
M
S
V
N
A
V
Site 20
S187
S
S
L
L
S
P
M
S
V
N
A
V
M
K
V
Site 21
T199
M
K
V
I
D
P
A
T
A
T
S
V
D
L
R
Site 22
T201
V
I
D
P
A
T
A
T
S
V
D
L
R
D
I
Site 23
S202
I
D
P
A
T
A
T
S
V
D
L
R
D
I
K
Site 24
T258
F
C
L
S
A
P
K
T
D
M
D
N
Q
I
V
Site 25
Y269
N
Q
I
V
V
S
D
Y
A
Q
M
D
R
V
L
Site 26
Y282
V
L
R
E
E
R
A
Y
I
L
N
L
V
K
Q
Site 27
T377
S
G
K
L
L
K
I
T
G
C
A
S
P
G
K
Site 28
S381
L
K
I
T
G
C
A
S
P
G
K
T
V
T
I
Site 29
T387
A
S
P
G
K
T
V
T
I
V
V
R
G
S
N
Site 30
T437
I
E
L
A
L
R
L
T
E
Y
S
R
T
L
S
Site 31
Y439
L
A
L
R
L
T
E
Y
S
R
T
L
S
G
M
Site 32
S440
A
L
R
L
T
E
Y
S
R
T
L
S
G
M
E
Site 33
T442
R
L
T
E
Y
S
R
T
L
S
G
M
E
S
Y
Site 34
S444
T
E
Y
S
R
T
L
S
G
M
E
S
Y
C
V
Site 35
S448
R
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
Site 36
Y449
T
L
S
G
M
E
S
Y
C
V
R
A
F
A
D
Site 37
S463
D
A
M
E
V
I
P
S
T
L
A
E
N
A
G
Site 38
T464
A
M
E
V
I
P
S
T
L
A
E
N
A
G
L
Site 39
S475
N
A
G
L
N
P
I
S
T
V
T
E
L
R
N
Site 40
T476
A
G
L
N
P
I
S
T
V
T
E
L
R
N
R
Site 41
S501
N
V
R
K
G
G
I
S
N
I
L
E
E
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation