KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TUB
Full Name:
Tubby protein homolog
Alias:
Type:
Mass (Da):
55651
Number AA:
506
UniProt ID:
P50607
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
H
S
D
W
I
P
Y
S
V
L
D
D
E
G
R
Site 2
S58
N
A
D
G
R
P
R
S
R
R
A
R
Q
S
E
Site 3
S64
R
S
R
R
A
R
Q
S
E
E
Q
A
P
L
V
Site 4
S73
E
Q
A
P
L
V
E
S
Y
L
S
S
S
G
S
Site 5
Y74
Q
A
P
L
V
E
S
Y
L
S
S
S
G
S
T
Site 6
S76
P
L
V
E
S
Y
L
S
S
S
G
S
T
S
Y
Site 7
S77
L
V
E
S
Y
L
S
S
S
G
S
T
S
Y
Q
Site 8
S78
V
E
S
Y
L
S
S
S
G
S
T
S
Y
Q
V
Site 9
S80
S
Y
L
S
S
S
G
S
T
S
Y
Q
V
Q
E
Site 10
S82
L
S
S
S
G
S
T
S
Y
Q
V
Q
E
A
D
Site 11
S90
Y
Q
V
Q
E
A
D
S
L
A
S
V
Q
L
G
Site 12
T102
Q
L
G
A
T
R
P
T
A
P
A
S
A
K
R
Site 13
S106
T
R
P
T
A
P
A
S
A
K
R
T
K
A
A
Site 14
T110
A
P
A
S
A
K
R
T
K
A
A
A
T
A
G
Site 15
T115
K
R
T
K
A
A
A
T
A
G
G
Q
G
G
A
Site 16
S145
A
A
L
A
E
D
K
S
E
A
Q
G
P
V
Q
Site 17
T155
Q
G
P
V
Q
I
L
T
V
G
Q
S
D
H
A
Site 18
S177
A
G
G
G
E
R
P
S
G
Q
D
L
R
A
T
Site 19
T184
S
G
Q
D
L
R
A
T
M
Q
R
K
G
I
S
Site 20
S191
T
M
Q
R
K
G
I
S
S
S
M
S
F
D
E
Site 21
S192
M
Q
R
K
G
I
S
S
S
M
S
F
D
E
D
Site 22
S193
Q
R
K
G
I
S
S
S
M
S
F
D
E
D
E
Site 23
S195
K
G
I
S
S
S
M
S
F
D
E
D
E
E
D
Site 24
S207
E
E
D
E
E
E
N
S
S
S
S
S
Q
L
N
Site 25
S208
E
D
E
E
E
N
S
S
S
S
S
Q
L
N
S
Site 26
S209
D
E
E
E
N
S
S
S
S
S
Q
L
N
S
N
Site 27
S211
E
E
N
S
S
S
S
S
Q
L
N
S
N
T
R
Site 28
S215
S
S
S
S
Q
L
N
S
N
T
R
P
S
S
A
Site 29
T217
S
S
Q
L
N
S
N
T
R
P
S
S
A
T
S
Site 30
S220
L
N
S
N
T
R
P
S
S
A
T
S
R
K
S
Site 31
S221
N
S
N
T
R
P
S
S
A
T
S
R
K
S
V
Site 32
T223
N
T
R
P
S
S
A
T
S
R
K
S
V
R
E
Site 33
S224
T
R
P
S
S
A
T
S
R
K
S
V
R
E
A
Site 34
S227
S
S
A
T
S
R
K
S
V
R
E
A
A
S
A
Site 35
S233
K
S
V
R
E
A
A
S
A
P
S
P
T
A
P
Site 36
S236
R
E
A
A
S
A
P
S
P
T
A
P
E
Q
P
Site 37
T270
I
T
I
K
C
R
I
T
R
D
K
K
G
M
D
Site 38
Y281
K
G
M
D
R
G
M
Y
P
T
Y
F
L
H
L
Site 39
Y284
D
R
G
M
Y
P
T
Y
F
L
H
L
D
R
E
Site 40
S307
A
G
R
K
R
K
K
S
K
T
S
N
Y
L
I
Site 41
T309
R
K
R
K
K
S
K
T
S
N
Y
L
I
S
V
Site 42
S315
K
T
S
N
Y
L
I
S
V
D
P
T
D
L
S
Site 43
T319
Y
L
I
S
V
D
P
T
D
L
S
R
G
G
D
Site 44
S322
S
V
D
P
T
D
L
S
R
G
G
D
S
Y
I
Site 45
S327
D
L
S
R
G
G
D
S
Y
I
G
K
L
R
S
Site 46
Y328
L
S
R
G
G
D
S
Y
I
G
K
L
R
S
N
Site 47
S334
S
Y
I
G
K
L
R
S
N
L
M
G
T
K
F
Site 48
Y344
M
G
T
K
F
T
V
Y
D
N
G
V
N
P
Q
Site 49
S354
G
V
N
P
Q
K
A
S
S
S
T
L
E
S
G
Site 50
S355
V
N
P
Q
K
A
S
S
S
T
L
E
S
G
T
Site 51
S356
N
P
Q
K
A
S
S
S
T
L
E
S
G
T
L
Site 52
S360
A
S
S
S
T
L
E
S
G
T
L
R
Q
E
L
Site 53
T362
S
S
T
L
E
S
G
T
L
R
Q
E
L
A
A
Site 54
Y372
Q
E
L
A
A
V
C
Y
E
T
N
V
L
G
F
Site 55
S386
F
K
G
P
R
K
M
S
V
I
V
P
G
M
N
Site 56
S400
N
M
V
H
E
R
V
S
I
R
P
R
N
E
H
Site 57
T409
R
P
R
N
E
H
E
T
L
L
A
R
W
Q
N
Site 58
T429
I
I
E
L
Q
N
K
T
P
V
W
N
D
D
T
Site 59
Y439
W
N
D
D
T
Q
S
Y
V
L
N
F
H
G
R
Site 60
T448
L
N
F
H
G
R
V
T
Q
A
S
V
K
N
F
Site 61
S451
H
G
R
V
T
Q
A
S
V
K
N
F
Q
I
I
Site 62
Y465
I
H
G
N
D
P
D
Y
I
V
M
Q
F
G
R
Site 63
T479
R
V
A
E
D
V
F
T
M
D
Y
N
Y
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation