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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LHX2
Full Name:
LIM/homeobox protein Lhx2
Alias:
Homeobox LH-2; LH2; LH-2; LIM homeobox 2; LIM HOX gene 2
Type:
Transcription factor
Mass (Da):
44373
Number AA:
406
UniProt ID:
P50458
International Prot ID:
IPI00032144
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
E
M
D
R
R
A
K
S
E
A
P
A
I
S
S
Site 2
T38
S
A
I
D
R
G
D
T
E
T
T
M
P
S
I
Site 3
T40
I
D
R
G
D
T
E
T
T
M
P
S
I
S
S
Site 4
T41
D
R
G
D
T
E
T
T
M
P
S
I
S
S
D
Site 5
S44
D
T
E
T
T
M
P
S
I
S
S
D
R
A
A
Site 6
S46
E
T
T
M
P
S
I
S
S
D
R
A
A
L
C
Site 7
S47
T
T
M
P
S
I
S
S
D
R
A
A
L
C
A
Site 8
Y64
G
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Site 9
Y65
G
K
I
S
D
R
Y
Y
L
L
A
V
D
K
Q
Site 10
T92
L
N
L
E
S
E
L
T
C
F
S
K
D
G
S
Site 11
S95
E
S
E
L
T
C
F
S
K
D
G
S
I
Y
C
Site 12
Y106
S
I
Y
C
K
E
D
Y
Y
R
R
F
S
V
Q
Site 13
Y107
I
Y
C
K
E
D
Y
Y
R
R
F
S
V
Q
R
Site 14
Y164
G
M
K
D
S
L
V
Y
C
R
L
H
F
E
A
Site 15
Y177
E
A
L
L
Q
G
E
Y
P
A
H
F
N
H
A
Site 16
Y213
A
N
P
L
G
L
P
Y
Y
N
G
V
G
T
V
Site 17
Y214
N
P
L
G
L
P
Y
Y
N
G
V
G
T
V
Q
Site 18
T219
P
Y
Y
N
G
V
G
T
V
Q
K
G
R
P
R
Site 19
S230
G
R
P
R
K
R
K
S
P
G
P
G
A
D
L
Site 20
S245
A
A
Y
N
A
A
L
S
C
N
E
N
D
A
E
Site 21
Y260
H
L
D
R
D
Q
P
Y
P
S
S
Q
K
T
K
Site 22
S263
R
D
Q
P
Y
P
S
S
Q
K
T
K
R
M
R
Site 23
T266
P
Y
P
S
S
Q
K
T
K
R
M
R
T
S
F
Site 24
T271
Q
K
T
K
R
M
R
T
S
F
K
H
H
Q
L
Site 25
S272
K
T
K
R
M
R
T
S
F
K
H
H
Q
L
R
Site 26
Y284
Q
L
R
T
M
K
S
Y
F
A
I
N
H
N
P
Site 27
T303
L
K
Q
L
A
Q
K
T
G
L
T
K
R
V
L
Site 28
T306
L
A
Q
K
T
G
L
T
K
R
V
L
Q
V
W
Site 29
T331
N
L
L
R
Q
E
N
T
G
V
D
K
S
T
D
Site 30
S336
E
N
T
G
V
D
K
S
T
D
A
A
L
Q
T
Site 31
T343
S
T
D
A
A
L
Q
T
G
T
P
S
G
P
A
Site 32
T345
D
A
A
L
Q
T
G
T
P
S
G
P
A
S
E
Site 33
S347
A
L
Q
T
G
T
P
S
G
P
A
S
E
L
S
Site 34
S351
G
T
P
S
G
P
A
S
E
L
S
N
A
S
L
Site 35
S354
S
G
P
A
S
E
L
S
N
A
S
L
S
P
S
Site 36
S357
A
S
E
L
S
N
A
S
L
S
P
S
S
T
P
Site 37
S359
E
L
S
N
A
S
L
S
P
S
S
T
P
T
T
Site 38
S361
S
N
A
S
L
S
P
S
S
T
P
T
T
L
T
Site 39
S362
N
A
S
L
S
P
S
S
T
P
T
T
L
T
D
Site 40
T363
A
S
L
S
P
S
S
T
P
T
T
L
T
D
L
Site 41
T365
L
S
P
S
S
T
P
T
T
L
T
D
L
T
S
Site 42
T366
S
P
S
S
T
P
T
T
L
T
D
L
T
S
P
Site 43
T368
S
S
T
P
T
T
L
T
D
L
T
S
P
T
L
Site 44
S396
L
E
G
H
E
P
H
S
P
S
Q
T
T
L
T
Site 45
S398
G
H
E
P
H
S
P
S
Q
T
T
L
T
N
L
Site 46
T400
E
P
H
S
P
S
Q
T
T
L
T
N
L
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation