PhosphoNET

           
Protein Info 
   
Short Name:  VEGFC
Full Name:  Vascular endothelial growth factor C
Alias:  Flt4 ligand; Flt4 ligand dhm; Flt4-l; Vascular endothelial growth factor c; Vascular endothelial growth factor-related protein; Vegfc; Vegf-c; Vrp
Type:  Secreted protein - Growth factor
Mass (Da):  46883
Number AA:  419
UniProt ID:  P49767
International Prot ID:  IPI00028076
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016020  GO:0031093   Uniprot OncoNet
Molecular Function:  GO:0008083     PhosphoSite+ KinaseNET
Biological Process:  GO:0001525  GO:0051781  GO:0006929 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S39FESGLDLSDAEPDAG
Site 2Y51DAGEATAYASKDLEE
Site 3S62DLEEQLRSVSSVDEL
Site 4S64EEQLRSVSSVDELMT
Site 5S65EQLRSVSSVDELMTV
Site 6T71SSVDELMTVLYPEYW
Site 7Y74DELMTVLYPEYWKMY
Site 8S101REQANLNSRTEETIK
Site 9T106LNSRTEETIKFAAAH
Site 10Y160KPPCVSVYRCGGCCN
Site 11T176EGLQCMNTSTSYLSK
Site 12S177GLQCMNTSTSYLSKT
Site 13S179QCMNTSTSYLSKTLF
Site 14Y180CMNTSTSYLSKTLFE
Site 15T189SKTLFEITVPLSQGP
Site 16S193FEITVPLSQGPKPVT
Site 17T200SQGPKPVTISFANHT
Site 18S202GPKPVTISFANHTSC
Site 19T207TISFANHTSCRCMSK
Site 20S223DVYRQVHSIIRRSLP
Site 21S228VHSIIRRSLPATLPQ
Site 22T232IRRSLPATLPQCQAA
Site 23S266QEDFMFSSDAGDDST
Site 24S272SSDAGDDSTDGFHDI
Site 25T273SDAGDDSTDGFHDIC
Site 26S303RAGLRPASCGPHKEL
Site 27S326CKNKLFPSQCGANRE
Site 28S400KACEPGFSYSEEVCR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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