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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RBM25
Full Name:
RNA-binding protein 25
Alias:
Arg/Glu/Asp-rich protein of 120 kDa; FSAP94; Functional spliceosome-associated protein 94; NET52; Protein S164; RNA binding motif protein 25; RNA-binding motif protein 25; RNA-binding region-containing protein 7; RNPC7; S164; YS64
Type:
RNA binding protein
Mass (Da):
100185
Number AA:
843
UniProt ID:
P49756
International Prot ID:
IPI00004273
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0003729
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S99
G
N
I
S
E
K
A
S
D
M
L
I
R
Q
L
Site 2
S123
W
K
R
V
Q
G
A
S
G
K
L
Q
A
F
G
Site 3
Y134
Q
A
F
G
F
C
E
Y
K
E
P
E
S
T
L
Site 4
S139
C
E
Y
K
E
P
E
S
T
L
R
A
L
R
L
Site 5
T140
E
Y
K
E
P
E
S
T
L
R
A
L
R
L
L
Site 6
T165
L
V
K
V
D
A
K
T
K
A
Q
L
D
E
W
Site 7
S179
W
K
A
K
K
K
A
S
N
G
N
A
R
P
E
Site 8
T187
N
G
N
A
R
P
E
T
V
T
N
D
D
E
E
Site 9
T189
N
A
R
P
E
T
V
T
N
D
D
E
E
A
L
Site 10
T200
E
E
A
L
D
E
E
T
K
R
R
D
Q
M
I
Site 11
Y218
I
E
V
L
I
R
E
Y
S
S
E
L
N
A
P
Site 12
S219
E
V
L
I
R
E
Y
S
S
E
L
N
A
P
S
Site 13
S226
S
S
E
L
N
A
P
S
Q
E
S
D
S
H
P
Site 14
S231
A
P
S
Q
E
S
D
S
H
P
R
K
K
K
K
Site 15
Y256
P
V
A
P
L
I
P
Y
P
L
I
T
K
E
D
Site 16
S278
E
D
K
R
D
L
I
S
R
E
I
S
K
F
R
Site 17
S282
D
L
I
S
R
E
I
S
K
F
R
D
T
H
K
Site 18
T287
E
I
S
K
F
R
D
T
H
K
K
L
E
E
E
Site 19
T354
R
D
R
D
R
D
R
T
K
E
R
D
R
D
R
Site 20
S374
R
D
R
D
R
E
R
S
S
D
R
N
K
D
R
Site 21
S375
D
R
D
R
E
R
S
S
D
R
N
K
D
R
S
Site 22
S382
S
D
R
N
K
D
R
S
R
S
R
E
K
S
R
Site 23
S384
R
N
K
D
R
S
R
S
R
E
K
S
R
D
R
Site 24
S388
R
S
R
S
R
E
K
S
R
D
R
E
R
S
E
Site 25
Y441
E
E
D
E
E
D
A
Y
E
R
R
K
L
E
R
Site 26
Y457
L
R
E
K
E
A
A
Y
Q
E
R
L
K
N
W
Site 27
T472
E
I
R
E
R
K
K
T
R
E
Y
E
K
E
A
Site 28
Y475
E
R
K
K
T
R
E
Y
E
K
E
A
E
R
E
Site 29
Y503
L
K
E
F
L
E
D
Y
D
D
D
R
D
D
P
Site 30
Y512
D
D
R
D
D
P
K
Y
Y
R
G
S
A
L
Q
Site 31
S516
D
P
K
Y
Y
R
G
S
A
L
Q
K
R
L
R
Site 32
S583
Q
I
K
Q
E
P
E
S
E
E
E
E
E
E
K
Site 33
T616
Q
K
P
C
L
K
P
T
L
R
P
I
S
S
A
Site 34
S621
K
P
T
L
R
P
I
S
S
A
P
S
V
S
S
Site 35
S622
P
T
L
R
P
I
S
S
A
P
S
V
S
S
A
Site 36
S625
R
P
I
S
S
A
P
S
V
S
S
A
S
G
N
Site 37
S628
S
S
A
P
S
V
S
S
A
S
G
N
A
T
P
Site 38
T634
S
S
A
S
G
N
A
T
P
N
T
P
G
D
E
Site 39
T637
S
G
N
A
T
P
N
T
P
G
D
E
S
P
C
Site 40
S642
P
N
T
P
G
D
E
S
P
C
G
I
I
I
P
Site 41
S653
I
I
I
P
H
E
N
S
P
D
Q
Q
Q
P
E
Site 42
S669
H
R
P
K
I
G
L
S
L
K
L
G
A
S
N
Site 43
S675
L
S
L
K
L
G
A
S
N
S
P
G
Q
P
N
Site 44
S677
L
K
L
G
A
S
N
S
P
G
Q
P
N
S
V
Site 45
S683
N
S
P
G
Q
P
N
S
V
K
R
K
K
L
P
Site 46
S693
R
K
K
L
P
V
D
S
V
F
N
K
F
E
D
Site 47
S703
N
K
F
E
D
E
D
S
D
D
V
P
R
K
R
Site 48
Y717
R
K
L
V
P
L
D
Y
G
E
D
D
K
N
A
Site 49
T728
D
K
N
A
T
K
G
T
V
N
T
E
E
K
R
Site 50
S740
E
K
R
K
H
I
K
S
L
I
E
K
I
P
T
Site 51
S802
C
S
K
V
M
A
H
S
S
P
Q
S
I
L
D
Site 52
S803
S
K
V
M
A
H
S
S
P
Q
S
I
L
D
D
Site 53
S806
M
A
H
S
S
P
Q
S
I
L
D
D
V
A
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation