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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COMP
Full Name:
Cartilage oligomeric matrix protein
Alias:
Thrombospondin-5
Type:
Mass (Da):
82860
Number AA:
757
UniProt ID:
P49747
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
G
A
S
G
Q
G
Q
S
P
L
G
S
D
L
G
Site 2
S28
Q
G
Q
S
P
L
G
S
D
L
G
P
Q
M
L
Site 3
T41
M
L
R
E
L
Q
E
T
N
A
A
L
Q
D
V
Site 4
T60
R
Q
Q
V
R
E
I
T
F
L
K
N
T
V
M
Site 5
S77
D
A
C
G
M
Q
Q
S
V
R
T
G
L
P
S
Site 6
T119
G
P
C
P
A
G
F
T
G
N
G
S
H
C
T
Site 7
S123
A
G
F
T
G
N
G
S
H
C
T
D
V
N
E
Site 8
S146
R
V
R
C
I
N
T
S
P
G
F
R
C
E
A
Site 9
Y158
C
E
A
C
P
P
G
Y
S
G
P
T
H
Q
G
Site 10
S219
G
F
V
G
D
Q
A
S
G
C
Q
R
R
A
Q
Site 11
S233
Q
R
F
C
P
D
G
S
P
S
E
C
H
E
H
Site 12
S235
F
C
P
D
G
S
P
S
E
C
H
E
H
A
D
Site 13
S252
L
E
R
D
G
S
R
S
C
V
C
A
V
G
W
Site 14
T270
G
I
L
C
G
R
D
T
D
L
D
G
F
P
D
Site 15
T294
C
R
K
D
N
C
V
T
V
P
N
S
G
Q
E
Site 16
T339
R
N
P
D
Q
R
N
T
D
E
D
K
W
G
D
Site 17
T362
K
N
D
D
Q
K
D
T
D
Q
D
G
R
G
D
Site 18
S393
N
C
P
R
V
P
N
S
D
Q
K
D
S
D
G
Site 19
S398
P
N
S
D
Q
K
D
S
D
G
D
G
I
G
D
Site 20
S432
F
V
G
D
A
C
D
S
D
Q
D
Q
D
G
D
Site 21
S444
D
G
D
G
H
Q
D
S
R
D
N
C
P
T
V
Site 22
T450
D
S
R
D
N
C
P
T
V
P
N
S
A
Q
E
Site 23
S454
N
C
P
T
V
P
N
S
A
Q
E
D
S
D
H
Site 24
S459
P
N
S
A
Q
E
D
S
D
H
D
G
Q
G
D
Site 25
S480
D
N
D
G
V
P
D
S
R
D
N
C
R
L
V
Site 26
T529
E
N
A
E
V
T
L
T
D
F
R
A
F
Q
T
Site 27
T536
T
D
F
R
A
F
Q
T
V
V
L
D
P
E
G
Site 28
T563
Q
G
R
E
I
V
Q
T
M
N
S
D
P
G
L
Site 29
T590
E
G
T
F
H
V
N
T
V
T
D
D
D
Y
A
Site 30
Y596
N
T
V
T
D
D
D
Y
A
G
F
I
F
G
Y
Site 31
Y603
Y
A
G
F
I
F
G
Y
Q
D
S
S
S
F
Y
Site 32
Y610
Y
Q
D
S
S
S
F
Y
V
V
M
W
K
Q
M
Site 33
S642
I
Q
L
K
A
V
K
S
S
T
G
P
G
E
Q
Site 34
Y694
Q
H
R
P
Q
V
G
Y
I
R
V
R
F
Y
E
Site 35
Y700
G
Y
I
R
V
R
F
Y
E
G
P
E
L
V
A
Site 36
T715
D
S
N
V
V
L
D
T
T
M
R
G
G
R
L
Site 37
T716
S
N
V
V
L
D
T
T
M
R
G
G
R
L
G
Site 38
Y749
N
D
T
I
P
E
D
Y
E
T
H
Q
L
R
Q
Site 39
T751
T
I
P
E
D
Y
E
T
H
Q
L
R
Q
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation