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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EVX1
Full Name:
Homeobox even-skipped homolog protein 1
Alias:
EVX-1
Type:
Mass (Da):
42440
Number AA:
407
UniProt ID:
P49640
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
G
K
R
V
S
N
L
S
E
A
V
G
S
P
L
Site 2
S33
N
L
S
E
A
V
G
S
P
L
P
E
P
P
E
Site 3
T57
P
R
A
V
P
P
A
T
R
E
R
G
G
G
G
Site 4
S100
G
P
G
P
P
A
P
S
V
D
S
L
S
G
Q
Site 5
S103
P
P
A
P
S
V
D
S
L
S
G
Q
G
Q
P
Site 6
S105
A
P
S
V
D
S
L
S
G
Q
G
Q
P
S
S
Site 7
S111
L
S
G
Q
G
Q
P
S
S
S
D
T
E
S
D
Site 8
S112
S
G
Q
G
Q
P
S
S
S
D
T
E
S
D
F
Site 9
S113
G
Q
G
Q
P
S
S
S
D
T
E
S
D
F
Y
Site 10
T115
G
Q
P
S
S
S
D
T
E
S
D
F
Y
E
E
Site 11
S117
P
S
S
S
D
T
E
S
D
F
Y
E
E
I
E
Site 12
Y120
S
D
T
E
S
D
F
Y
E
E
I
E
V
S
C
Site 13
T128
E
E
I
E
V
S
C
T
P
D
C
A
T
G
N
Site 14
T133
S
C
T
P
D
C
A
T
G
N
A
E
Y
Q
H
Site 15
Y138
C
A
T
G
N
A
E
Y
Q
H
S
K
G
S
G
Site 16
S141
G
N
A
E
Y
Q
H
S
K
G
S
G
S
E
A
Site 17
S144
E
Y
Q
H
S
K
G
S
G
S
E
A
L
V
G
Site 18
S146
Q
H
S
K
G
S
G
S
E
A
L
V
G
S
P
Site 19
S152
G
S
E
A
L
V
G
S
P
N
G
G
S
E
T
Site 20
S157
V
G
S
P
N
G
G
S
E
T
P
K
S
N
G
Site 21
T159
S
P
N
G
G
S
E
T
P
K
S
N
G
G
S
Site 22
S162
G
G
S
E
T
P
K
S
N
G
G
S
G
G
G
Site 23
S166
T
P
K
S
N
G
G
S
G
G
G
G
S
Q
G
Site 24
S171
G
G
S
G
G
G
G
S
Q
G
T
L
A
C
S
Site 25
T174
G
G
G
G
S
Q
G
T
L
A
C
S
A
S
D
Site 26
S178
S
Q
G
T
L
A
C
S
A
S
D
Q
M
R
R
Site 27
S180
G
T
L
A
C
S
A
S
D
Q
M
R
R
Y
R
Site 28
Y186
A
S
D
Q
M
R
R
Y
R
T
A
F
T
R
E
Site 29
T188
D
Q
M
R
R
Y
R
T
A
F
T
R
E
Q
I
Site 30
Y203
A
R
L
E
K
E
F
Y
R
E
N
Y
V
S
R
Site 31
Y207
K
E
F
Y
R
E
N
Y
V
S
R
P
R
R
C
Site 32
S209
F
Y
R
E
N
Y
V
S
R
P
R
R
C
E
L
Site 33
Y256
H
P
A
D
P
A
F
Y
T
Y
M
M
S
H
A
Site 34
S275
G
L
P
Y
P
F
P
S
H
L
P
L
P
Y
Y
Site 35
Y281
P
S
H
L
P
L
P
Y
Y
S
P
V
G
L
G
Site 36
S301
S
A
A
A
S
P
F
S
G
S
L
R
P
L
D
Site 37
S303
A
A
S
P
F
S
G
S
L
R
P
L
D
T
F
Site 38
T309
G
S
L
R
P
L
D
T
F
R
V
L
S
Q
P
Site 39
S314
L
D
T
F
R
V
L
S
Q
P
Y
P
R
P
E
Site 40
Y317
F
R
V
L
S
Q
P
Y
P
R
P
E
L
L
C
Site 41
Y332
A
F
R
H
P
P
L
Y
P
G
P
A
H
G
L
Site 42
T371
A
A
A
A
S
D
F
T
C
A
S
T
S
R
S
Site 43
S374
A
S
D
F
T
C
A
S
T
S
R
S
D
S
F
Site 44
T375
S
D
F
T
C
A
S
T
S
R
S
D
S
F
L
Site 45
S376
D
F
T
C
A
S
T
S
R
S
D
S
F
L
T
Site 46
S378
T
C
A
S
T
S
R
S
D
S
F
L
T
F
A
Site 47
S380
A
S
T
S
R
S
D
S
F
L
T
F
A
P
S
Site 48
S394
S
V
L
S
K
A
S
S
V
A
L
D
Q
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation