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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SARS
Full Name:
Seryl-tRNA synthetase, cytoplasmic
Alias:
FLJ36399; Serine tRNA ligase 1, cytoplasmic; Serine--tRNA ligase; SERRS; SERS; Seryl-tRNA synthetase; SYSC
Type:
EC 6.1.1.11; RNA processing; Ligase
Mass (Da):
58777
Number AA:
514
UniProt ID:
P49591
International Prot ID:
IPI00220637
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003723
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006434
GO:0008033
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
D
P
A
L
I
R
E
T
Q
E
K
R
F
K
D
Site 2
S41
D
Q
L
V
K
A
D
S
E
W
R
R
C
R
F
Site 3
S61
N
K
L
K
N
L
C
S
K
T
I
G
E
K
M
Site 4
T63
L
K
N
L
C
S
K
T
I
G
E
K
M
K
K
Site 5
S79
E
P
V
G
D
D
E
S
V
P
E
N
V
L
S
Site 6
S86
S
V
P
E
N
V
L
S
F
D
D
L
T
A
D
Site 7
S101
A
L
A
N
L
K
V
S
Q
I
K
K
V
R
L
Site 8
S142
I
G
N
L
L
H
P
S
V
P
I
S
N
D
E
Site 9
S146
L
H
P
S
V
P
I
S
N
D
E
D
V
D
N
Site 10
T163
E
R
I
W
G
D
C
T
V
R
K
K
Y
S
H
Site 11
Y168
D
C
T
V
R
K
K
Y
S
H
V
D
L
V
V
Site 12
Y220
R
T
L
G
S
R
G
Y
I
P
I
Y
T
P
F
Site 13
Y224
S
R
G
Y
I
P
I
Y
T
P
F
F
M
R
K
Site 14
T225
R
G
Y
I
P
I
Y
T
P
F
F
M
R
K
E
Site 15
S241
M
Q
E
V
A
Q
L
S
Q
F
D
E
E
L
Y
Site 16
Y248
S
Q
F
D
E
E
L
Y
K
V
I
G
K
G
S
Site 17
S255
Y
K
V
I
G
K
G
S
E
K
S
D
D
N
S
Site 18
S258
I
G
K
G
S
E
K
S
D
D
N
S
Y
D
E
Site 19
S262
S
E
K
S
D
D
N
S
Y
D
E
K
Y
L
I
Site 20
Y263
E
K
S
D
D
N
S
Y
D
E
K
Y
L
I
A
Site 21
Y267
D
N
S
Y
D
E
K
Y
L
I
A
T
S
E
Q
Site 22
S298
P
I
K
Y
A
G
L
S
T
C
F
R
Q
E
V
Site 23
S307
C
F
R
Q
E
V
G
S
H
G
R
D
T
R
G
Site 24
T312
V
G
S
H
G
R
D
T
R
G
I
F
R
V
H
Site 25
Y329
E
K
I
E
Q
F
V
Y
S
S
P
H
D
N
K
Site 26
S331
I
E
Q
F
V
Y
S
S
P
H
D
N
K
S
W
Site 27
T347
M
F
E
E
M
I
T
T
A
E
E
F
Y
Q
S
Site 28
Y352
I
T
T
A
E
E
F
Y
Q
S
L
G
I
P
Y
Site 29
S394
G
A
F
R
E
L
V
S
C
S
N
C
T
D
Y
Site 30
Y401
S
C
S
N
C
T
D
Y
Q
A
R
R
L
R
I
Site 31
Y410
A
R
R
L
R
I
R
Y
G
Q
T
K
K
M
M
Site 32
T446
A
I
L
E
N
Y
Q
T
E
K
G
I
T
V
P
Site 33
T451
Y
Q
T
E
K
G
I
T
V
P
E
K
L
K
E
Site 34
T501
K
A
A
A
R
D
V
T
L
E
N
R
L
Q
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation