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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GLUD2
Full Name:
Glutamate dehydrogenase 2, mitochondrial
Alias:
DHE4; EC 1.4.1.3; GDH; GDH2; GLUDP1
Type:
Mitochondrion, Mitochondrial matrix protein
Mass (Da):
61434
Number AA:
558
UniProt ID:
P49448
International Prot ID:
IPI00027146
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005759
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004352
GO:0004353
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006519
GO:0006520
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
A
K
A
L
L
P
S
R
A
G
P
A
A
L
Site 2
S41
R
G
Q
P
A
A
A
S
Q
P
G
L
A
L
A
Site 3
Y53
A
L
A
A
R
R
H
Y
S
E
L
V
A
D
R
Site 4
S54
L
A
A
R
R
H
Y
S
E
L
V
A
D
R
E
Site 5
S79
G
F
F
D
R
G
A
S
I
V
E
D
K
L
V
Site 6
T91
K
L
V
K
D
L
R
T
Q
E
S
E
E
Q
K
Site 7
S94
K
D
L
R
T
Q
E
S
E
E
Q
K
R
N
R
Site 8
S117
K
P
C
N
H
V
L
S
L
S
F
P
I
R
R
Site 9
S119
C
N
H
V
L
S
L
S
F
P
I
R
R
D
D
Site 10
S128
P
I
R
R
D
D
G
S
W
E
V
I
E
G
Y
Site 11
Y135
S
W
E
V
I
E
G
Y
R
A
Q
H
S
Q
H
Site 12
S140
E
G
Y
R
A
Q
H
S
Q
H
R
T
P
C
K
Site 13
T144
A
Q
H
S
Q
H
R
T
P
C
K
G
G
I
R
Site 14
Y152
P
C
K
G
G
I
R
Y
S
T
D
V
S
V
D
Site 15
S153
C
K
G
G
I
R
Y
S
T
D
V
S
V
D
E
Site 16
T154
K
G
G
I
R
Y
S
T
D
V
S
V
D
E
V
Site 17
S157
I
R
Y
S
T
D
V
S
V
D
E
V
K
A
L
Site 18
Y170
A
L
A
S
L
M
T
Y
K
C
A
V
V
D
V
Site 19
Y193
V
K
I
N
P
K
N
Y
T
E
N
E
L
E
K
Site 20
T206
E
K
I
T
R
R
F
T
M
E
L
A
K
K
G
Site 21
T228
V
P
A
P
D
M
N
T
G
E
R
E
M
S
W
Site 22
S234
N
T
G
E
R
E
M
S
W
I
A
D
T
Y
A
Site 23
Y240
M
S
W
I
A
D
T
Y
A
S
T
I
G
H
Y
Site 24
S261
C
V
T
G
K
P
I
S
Q
G
G
I
H
G
R
Site 25
T272
I
H
G
R
I
S
A
T
G
R
G
V
F
H
G
Site 26
T296
Y
M
S
I
L
G
M
T
P
G
F
R
D
K
T
Site 27
T303
T
P
G
F
R
D
K
T
F
V
V
Q
G
F
G
Site 28
Y319
V
G
L
H
S
M
R
Y
L
H
R
F
G
A
K
Site 29
S336
A
V
G
E
S
D
G
S
I
W
N
P
D
G
I
Site 30
S357
D
F
K
L
Q
H
G
S
I
L
G
F
P
K
A
Site 31
Y367
G
F
P
K
A
K
P
Y
E
G
S
I
L
E
V
Site 32
T389
A
A
T
E
K
Q
L
T
K
S
N
A
P
R
V
Site 33
S391
T
E
K
Q
L
T
K
S
N
A
P
R
V
K
A
Site 34
T409
A
E
G
A
N
G
P
T
T
P
E
A
D
K
I
Site 35
T410
E
G
A
N
G
P
T
T
P
E
A
D
K
I
F
Site 36
S438
N
A
G
G
V
T
V
S
Y
F
E
W
L
K
N
Site 37
Y439
A
G
G
V
T
V
S
Y
F
E
W
L
K
N
L
Site 38
S450
L
K
N
L
N
H
V
S
Y
G
R
L
T
F
K
Site 39
Y451
K
N
L
N
H
V
S
Y
G
R
L
T
F
K
Y
Site 40
T455
H
V
S
Y
G
R
L
T
F
K
Y
E
R
D
S
Site 41
Y458
Y
G
R
L
T
F
K
Y
E
R
D
S
N
Y
H
Site 42
S462
T
F
K
Y
E
R
D
S
N
Y
H
L
L
L
S
Site 43
Y464
K
Y
E
R
D
S
N
Y
H
L
L
L
S
V
Q
Site 44
S469
S
N
Y
H
L
L
L
S
V
Q
E
S
L
E
R
Site 45
S473
L
L
L
S
V
Q
E
S
L
E
R
K
F
G
K
Site 46
S496
P
T
A
E
F
Q
D
S
I
S
G
A
S
E
K
Site 47
S498
A
E
F
Q
D
S
I
S
G
A
S
E
K
D
I
Site 48
Y512
I
V
H
S
A
L
A
Y
T
M
E
R
S
A
R
Site 49
T524
S
A
R
Q
I
M
H
T
A
M
K
Y
N
L
G
Site 50
Y528
I
M
H
T
A
M
K
Y
N
L
G
L
D
L
R
Site 51
Y539
L
D
L
R
T
A
A
Y
V
N
A
I
E
K
V
Site 52
S551
E
K
V
F
K
V
Y
S
E
A
G
V
T
F
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation