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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GSS
Full Name:
Glutathione synthetase
Alias:
Glutathione synthase
Type:
Mass (Da):
52367
Number AA:
474
UniProt ID:
P48637
International Prot ID:
IPI00010706
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0004363
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006519
GO:0006520
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
E
G
V
L
L
R
T
S
Q
E
P
T
S
S
E
Site 2
T40
L
R
T
S
Q
E
P
T
S
S
E
V
V
S
Y
Site 3
S41
R
T
S
Q
E
P
T
S
S
E
V
V
S
Y
A
Site 4
S42
T
S
Q
E
P
T
S
S
E
V
V
S
Y
A
P
Site 5
S91
A
F
L
E
Q
T
L
S
S
T
I
K
Q
D
D
Site 6
T100
T
I
K
Q
D
D
F
T
A
R
L
F
D
I
H
Site 7
S126
V
F
L
G
L
N
R
S
D
Y
M
F
Q
R
S
Site 8
Y128
L
G
L
N
R
S
D
Y
M
F
Q
R
S
A
D
Site 9
S133
S
D
Y
M
F
Q
R
S
A
D
G
S
P
A
L
Site 10
S137
F
Q
R
S
A
D
G
S
P
A
L
K
Q
I
E
Site 11
T147
L
K
Q
I
E
I
N
T
I
S
A
S
F
G
G
Site 12
S151
E
I
N
T
I
S
A
S
F
G
G
L
A
S
R
Site 13
S157
A
S
F
G
G
L
A
S
R
T
P
A
V
H
R
Site 14
T159
F
G
G
L
A
S
R
T
P
A
V
H
R
H
V
Site 15
S168
A
V
H
R
H
V
L
S
V
L
S
K
T
K
E
Site 16
S181
K
E
A
G
K
I
L
S
N
N
P
S
K
G
L
Site 17
T238
N
I
H
V
I
R
R
T
F
E
D
I
S
E
K
Site 18
S243
R
R
T
F
E
D
I
S
E
K
G
S
L
D
Q
Site 19
S247
E
D
I
S
E
K
G
S
L
D
Q
D
R
R
L
Site 20
Y265
G
Q
E
I
A
V
V
Y
F
R
D
G
Y
M
P
Site 21
Y270
V
V
Y
F
R
D
G
Y
M
P
R
Q
Y
S
L
Site 22
Y275
D
G
Y
M
P
R
Q
Y
S
L
Q
N
W
E
A
Site 23
S276
G
Y
M
P
R
Q
Y
S
L
Q
N
W
E
A
R
Site 24
S289
A
R
L
L
L
E
R
S
H
A
A
K
C
P
D
Site 25
T299
A
K
C
P
D
I
A
T
Q
L
A
G
T
K
K
Site 26
Y339
R
A
T
F
A
G
L
Y
S
L
D
V
G
E
E
Site 27
Y375
E
G
G
G
N
N
L
Y
G
E
E
M
V
Q
A
Site 28
S389
A
L
K
Q
L
K
D
S
E
E
R
A
S
Y
I
Site 29
S394
K
D
S
E
E
R
A
S
Y
I
L
M
E
K
I
Site 30
Y395
D
S
E
E
R
A
S
Y
I
L
M
E
K
I
E
Site 31
S415
N
C
L
L
R
P
G
S
P
A
R
V
V
Q
C
Site 32
T438
V
Y
V
R
Q
E
K
T
L
V
M
N
K
H
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation