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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINB10
Full Name:
Serpin B10
Alias:
Bomapin; PI10; Protease inhibitor 10; SPB10
Type:
Protease inhibitor
Mass (Da):
45403
Number AA:
397
UniProt ID:
P48595
International Prot ID:
IPI00010304
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004867
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
Q
G
K
N
I
F
F
S
S
W
S
I
S
T
S
Site 2
S72
G
V
K
C
D
P
E
S
E
K
K
R
K
M
E
Site 3
S83
R
K
M
E
F
N
L
S
N
S
E
E
I
H
S
Site 4
S85
M
E
F
N
L
S
N
S
E
E
I
H
S
D
F
Site 5
S90
S
N
S
E
E
I
H
S
D
F
Q
T
L
I
S
Site 6
T94
E
I
H
S
D
F
Q
T
L
I
S
E
I
L
K
Site 7
Y106
I
L
K
P
N
D
D
Y
L
L
K
T
A
N
A
Site 8
Y126
T
Y
A
F
H
N
K
Y
L
E
D
M
K
T
Y
Site 9
T132
K
Y
L
E
D
M
K
T
Y
F
G
A
E
P
Q
Site 10
Y133
Y
L
E
D
M
K
T
Y
F
G
A
E
P
Q
P
Site 11
S156
Q
I
R
K
D
I
N
S
W
V
E
R
Q
T
E
Site 12
T162
N
S
W
V
E
R
Q
T
E
G
K
I
Q
N
L
Site 13
S174
Q
N
L
L
P
D
D
S
V
D
S
T
T
R
M
Site 14
T178
P
D
D
S
V
D
S
T
T
R
M
I
L
V
N
Site 15
T203
Q
F
L
V
Q
N
T
T
E
K
P
F
R
I
N
Site 16
T213
P
F
R
I
N
E
T
T
S
K
P
V
Q
M
M
Site 17
Y242
K
A
V
G
L
Q
L
Y
Y
K
S
R
D
L
S
Site 18
Y243
A
V
G
L
Q
L
Y
Y
K
S
R
D
L
S
L
Site 19
T269
E
Q
L
E
K
A
I
T
Y
E
K
L
N
E
W
Site 20
Y285
S
A
D
M
M
E
L
Y
E
V
Q
L
H
L
P
Site 21
S299
P
K
F
K
L
E
D
S
Y
D
L
K
S
T
L
Site 22
Y300
K
F
K
L
E
D
S
Y
D
L
K
S
T
L
S
Site 23
S304
E
D
S
Y
D
L
K
S
T
L
S
S
M
G
M
Site 24
T305
D
S
Y
D
L
K
S
T
L
S
S
M
G
M
S
Site 25
S307
Y
D
L
K
S
T
L
S
S
M
G
M
S
D
A
Site 26
S308
D
L
K
S
T
L
S
S
M
G
M
S
D
A
F
Site 27
S312
T
L
S
S
M
G
M
S
D
A
F
S
Q
S
K
Site 28
S316
M
G
M
S
D
A
F
S
Q
S
K
A
D
F
S
Site 29
S318
M
S
D
A
F
S
Q
S
K
A
D
F
S
G
M
Site 30
S323
S
Q
S
K
A
D
F
S
G
M
S
S
A
R
N
Site 31
S327
A
D
F
S
G
M
S
S
A
R
N
L
F
L
S
Site 32
S357
E
A
A
A
G
S
G
S
E
I
D
I
R
I
R
Site 33
S367
D
I
R
I
R
V
P
S
I
E
F
N
A
N
H
Site 34
Y391
K
T
N
T
I
L
F
Y
G
R
L
C
S
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation