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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINB4
Full Name:
Serpin B4
Alias:
LEUPIN; PI11; Protease inhibitor (leucine-serpin); SCCA1; SCCA2; SCCA-2; Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; Serpin peptidase inhibitor, clade B (ovalbumin), member 4; SPB4; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2
Type:
Protease inhibitor
Mass (Da):
44854
Number AA:
390
UniProt ID:
P48594
International Prot ID:
IPI00010303
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004867
PhosphoSite+
KinaseNET
Biological Process:
GO:0006955
GO:0030162
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
N
S
L
S
E
A
N
T
K
F
M
F
D
L
F
Site 2
Y29
S
K
E
N
N
I
F
Y
S
P
I
S
I
T
S
Site 3
S30
K
E
N
N
I
F
Y
S
P
I
S
I
T
S
A
Site 4
Y73
T
T
E
K
A
A
T
Y
H
V
D
R
S
G
N
Site 5
T90
H
Q
F
Q
K
L
L
T
E
F
N
K
S
T
D
Site 6
S95
L
L
T
E
F
N
K
S
T
D
A
Y
E
L
K
Site 7
Y99
F
N
K
S
T
D
A
Y
E
L
K
I
A
N
K
Site 8
T112
N
K
L
F
G
E
K
T
Y
Q
F
L
Q
E
Y
Site 9
Y119
T
Y
Q
F
L
Q
E
Y
L
D
A
I
K
K
F
Site 10
Y127
L
D
A
I
K
K
F
Y
Q
T
S
V
E
S
T
Site 11
T129
A
I
K
K
F
Y
Q
T
S
V
E
S
T
D
F
Site 12
S130
I
K
K
F
Y
Q
T
S
V
E
S
T
D
F
A
Site 13
S149
E
S
R
K
K
I
N
S
W
V
E
S
Q
T
N
Site 14
S153
K
I
N
S
W
V
E
S
Q
T
N
E
K
I
K
Site 15
T167
K
N
L
F
P
D
G
T
I
G
N
D
T
T
L
Site 16
Y216
S
V
Q
M
M
R
Q
Y
N
S
F
N
F
A
L
Site 17
T262
Q
K
L
E
E
K
L
T
A
E
K
L
M
E
W
Site 18
S271
E
K
L
M
E
W
T
S
L
Q
N
M
R
E
T
Site 19
T278
S
L
Q
N
M
R
E
T
C
V
D
L
H
L
P
Site 20
T298
E
S
Y
D
L
K
D
T
L
R
T
M
G
M
V
Site 21
S320
D
L
S
G
M
T
W
S
H
G
L
S
V
S
K
Site 22
S324
M
T
W
S
H
G
L
S
V
S
K
V
L
H
K
Site 23
S326
W
S
H
G
L
S
V
S
K
V
L
H
K
A
F
Site 24
T347
G
V
E
A
A
A
A
T
A
V
V
V
V
E
L
Site 25
S355
A
V
V
V
V
E
L
S
S
P
S
T
N
E
E
Site 26
S356
V
V
V
V
E
L
S
S
P
S
T
N
E
E
F
Site 27
T359
V
E
L
S
S
P
S
T
N
E
E
F
C
C
N
Site 28
Y384
K
T
N
S
I
L
F
Y
G
R
F
S
S
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation