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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRAPPC10
Full Name:
Trafficking protein particle complex subunit 10
Alias:
EHOC1; Epilepsy holoprosencephaly candidate 1 protein; Epilepsy holoprosencephaly candidate-1 protein; GT334 protein; Protein GT334; TMEM1; Trafficking protein particle complex 10; Trafficking protein particle complex subunit 130; Trafficking protein particle complex subunit TMEM1; Transmembrane protein 1; Transport protein particle subunit TMEM1; TRAPP 130 kDa subunit; TRS130
Type:
Mass (Da):
142189
Number AA:
1259
UniProt ID:
P48553
International Prot ID:
IPI00298870
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
GO:0015081
GO:0008324
GO:0015075
PhosphoSite+
KinaseNET
Biological Process:
GO:0006814
GO:0016192
GO:0006812
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
G
D
Q
N
L
F
T
S
V
Y
P
T
L
S
Q
Site 2
Y34
Q
N
L
F
T
S
V
Y
P
T
L
S
Q
Q
L
Site 3
T36
L
F
T
S
V
Y
P
T
L
S
Q
Q
L
P
R
Site 4
S38
T
S
V
Y
P
T
L
S
Q
Q
L
P
R
E
P
Site 5
S51
E
P
M
E
W
R
R
S
Y
G
R
A
P
K
M
Site 6
Y52
P
M
E
W
R
R
S
Y
G
R
A
P
K
M
I
Site 7
T109
A
T
V
K
D
D
L
T
K
W
Q
N
V
L
K
Site 8
S145
T
N
I
L
P
R
T
S
I
V
D
K
I
R
N
Site 9
S166
S
D
R
C
V
V
L
S
D
P
L
K
D
S
S
Site 10
S172
L
S
D
P
L
K
D
S
S
R
T
Q
E
S
W
Site 11
S173
S
D
P
L
K
D
S
S
R
T
Q
E
S
W
N
Site 12
S178
D
S
S
R
T
Q
E
S
W
N
A
F
L
T
K
Site 13
T207
K
F
E
D
D
M
R
T
L
R
E
K
R
T
E
Site 14
T213
R
T
L
R
E
K
R
T
E
P
G
W
S
F
C
Site 15
Y222
P
G
W
S
F
C
E
Y
F
M
V
Q
E
E
L
Site 16
S295
I
D
M
E
K
R
E
S
I
Q
R
R
E
A
T
Site 17
T302
S
I
Q
R
R
E
A
T
L
L
D
L
R
S
Y
Site 18
Y309
T
L
L
D
L
R
S
Y
L
F
S
R
Q
C
T
Site 19
T393
V
G
L
W
S
Y
A
T
E
K
L
K
S
L
G
Site 20
S398
Y
A
T
E
K
L
K
S
L
G
Y
L
C
G
L
Site 21
Y401
E
K
L
K
S
L
G
Y
L
C
G
L
V
S
E
Site 22
S407
G
Y
L
C
G
L
V
S
E
K
G
P
N
S
E
Site 23
S413
V
S
E
K
G
P
N
S
E
D
L
N
R
T
V
Site 24
T419
N
S
E
D
L
N
R
T
V
D
L
L
A
G
L
Site 25
T433
L
G
A
E
R
P
E
T
A
N
T
A
Q
S
P
Site 26
T436
E
R
P
E
T
A
N
T
A
Q
S
P
Y
K
K
Site 27
S439
E
T
A
N
T
A
Q
S
P
Y
K
K
L
K
E
Site 28
S449
K
K
L
K
E
A
L
S
S
V
E
A
F
E
K
Site 29
S450
K
L
K
E
A
L
S
S
V
E
A
F
E
K
H
Site 30
Y458
V
E
A
F
E
K
H
Y
L
D
L
S
H
A
T
Site 31
Y469
S
H
A
T
I
E
M
Y
T
S
I
G
R
I
R
Site 32
S471
A
T
I
E
M
Y
T
S
I
G
R
I
R
S
A
Site 33
S477
T
S
I
G
R
I
R
S
A
K
F
V
G
K
D
Site 34
Y489
G
K
D
L
A
E
F
Y
M
R
K
K
A
P
Q
Site 35
Y501
A
P
Q
K
A
E
I
Y
L
Q
G
A
L
K
N
Site 36
T519
E
G
W
A
L
P
I
T
H
T
R
K
Q
L
A
Site 37
Y538
H
L
G
Q
I
E
N
Y
L
Q
T
S
S
L
L
Site 38
S543
E
N
Y
L
Q
T
S
S
L
L
A
S
D
H
H
Site 39
S547
Q
T
S
S
L
L
A
S
D
H
H
L
T
E
E
Site 40
T552
L
A
S
D
H
H
L
T
E
E
E
R
K
H
F
Site 41
S568
Q
E
I
L
D
F
A
S
Q
P
S
D
S
P
G
Site 42
S573
F
A
S
Q
P
S
D
S
P
G
H
K
I
V
L
Site 43
S596
R
D
L
H
F
D
P
S
N
A
V
V
H
V
G
Site 44
Y638
F
S
I
E
K
N
S
Y
R
K
T
A
E
W
L
Site 45
T641
E
K
N
S
Y
R
K
T
A
E
W
L
T
K
H
Site 46
T646
R
K
T
A
E
W
L
T
K
H
K
T
S
N
G
Site 47
S667
E
T
A
P
F
P
V
S
Q
N
S
L
P
A
L
Site 48
S670
P
F
P
V
S
Q
N
S
L
P
A
L
E
L
Y
Site 49
Y677
S
L
P
A
L
E
L
Y
E
M
F
E
R
S
P
Site 50
S683
L
Y
E
M
F
E
R
S
P
S
D
N
S
L
N
Site 51
S685
E
M
F
E
R
S
P
S
D
N
S
L
N
T
T
Site 52
S688
E
R
S
P
S
D
N
S
L
N
T
T
G
I
I
Site 53
T692
S
D
N
S
L
N
T
T
G
I
I
C
R
N
V
Site 54
S708
M
L
L
R
R
Q
E
S
S
S
S
L
E
M
P
Site 55
S709
L
L
R
R
Q
E
S
S
S
S
L
E
M
P
S
Site 56
S710
L
R
R
Q
E
S
S
S
S
L
E
M
P
S
G
Site 57
S711
R
R
Q
E
S
S
S
S
L
E
M
P
S
G
V
Site 58
S716
S
S
S
L
E
M
P
S
G
V
A
L
E
E
G
Site 59
T733
V
L
R
C
S
H
V
T
L
E
P
G
A
N
Q
Site 60
T742
E
P
G
A
N
Q
I
T
F
R
T
Q
A
K
E
Site 61
Y753
Q
A
K
E
P
G
T
Y
T
L
R
Q
L
C
A
Site 62
T754
A
K
E
P
G
T
Y
T
L
R
Q
L
C
A
S
Site 63
Y778
H
I
Y
P
I
V
Q
Y
D
V
Y
S
Q
E
P
Site 64
Y781
P
I
V
Q
Y
D
V
Y
S
Q
E
P
Q
L
H
Site 65
S782
I
V
Q
Y
D
V
Y
S
Q
E
P
Q
L
H
V
Site 66
S820
Y
T
I
K
N
G
D
S
L
Q
L
S
N
A
E
Site 67
S824
N
G
D
S
L
Q
L
S
N
A
E
A
M
L
I
Site 68
S843
E
S
R
A
V
V
Y
S
N
T
R
E
Q
S
S
Site 69
T845
R
A
V
V
Y
S
N
T
R
E
Q
S
S
E
A
Site 70
S849
Y
S
N
T
R
E
Q
S
S
E
A
A
L
R
I
Site 71
S850
S
N
T
R
E
Q
S
S
E
A
A
L
R
I
Q
Site 72
S858
E
A
A
L
R
I
Q
S
S
D
K
V
T
S
I
Site 73
S859
A
A
L
R
I
Q
S
S
D
K
V
T
S
I
S
Site 74
S864
Q
S
S
D
K
V
T
S
I
S
L
P
V
A
P
Site 75
T920
T
G
R
C
M
V
T
T
D
H
K
V
S
I
D
Site 76
Y933
I
D
C
P
W
S
I
Y
S
T
V
I
A
L
T
Site 77
T947
T
F
S
V
P
F
R
T
T
H
S
L
L
S
S
Site 78
T948
F
S
V
P
F
R
T
T
H
S
L
L
S
S
G
Site 79
S950
V
P
F
R
T
T
H
S
L
L
S
S
G
T
R
Site 80
S953
R
T
T
H
S
L
L
S
S
G
T
R
K
Y
V
Site 81
S954
T
T
H
S
L
L
S
S
G
T
R
K
Y
V
Q
Site 82
Y959
L
S
S
G
T
R
K
Y
V
Q
V
C
V
Q
N
Site 83
S975
S
E
L
D
F
Q
L
S
D
S
Y
L
V
D
T
Site 84
S977
L
D
F
Q
L
S
D
S
Y
L
V
D
T
G
D
Site 85
Y978
D
F
Q
L
S
D
S
Y
L
V
D
T
G
D
S
Site 86
T982
S
D
S
Y
L
V
D
T
G
D
S
T
D
L
Q
Site 87
T995
L
Q
L
V
P
L
N
T
Q
S
Q
Q
P
I
Y
Site 88
S997
L
V
P
L
N
T
Q
S
Q
Q
P
I
Y
S
K
Site 89
Y1002
T
Q
S
Q
Q
P
I
Y
S
K
Q
S
V
F
F
Site 90
S1003
Q
S
Q
Q
P
I
Y
S
K
Q
S
V
F
F
V
Site 91
T1016
F
V
W
E
L
K
W
T
E
E
P
P
P
S
L
Site 92
S1022
W
T
E
E
P
P
P
S
L
H
C
R
F
S
V
Site 93
S1028
P
S
L
H
C
R
F
S
V
G
F
S
P
A
S
Site 94
S1032
C
R
F
S
V
G
F
S
P
A
S
E
E
Q
L
Site 95
S1035
S
V
G
F
S
P
A
S
E
E
Q
L
S
I
S
Site 96
S1040
P
A
S
E
E
Q
L
S
I
S
L
K
P
Y
T
Site 97
S1042
S
E
E
Q
L
S
I
S
L
K
P
Y
T
Y
E
Site 98
Y1046
L
S
I
S
L
K
P
Y
T
Y
E
F
K
V
E
Site 99
T1047
S
I
S
L
K
P
Y
T
Y
E
F
K
V
E
N
Site 100
Y1048
I
S
L
K
P
Y
T
Y
E
F
K
V
E
N
F
Site 101
T1057
F
K
V
E
N
F
F
T
L
Y
N
V
K
A
E
Site 102
S1069
K
A
E
I
F
P
P
S
G
M
E
Y
C
R
T
Site 103
Y1073
F
P
P
S
G
M
E
Y
C
R
T
G
S
L
C
Site 104
T1076
S
G
M
E
Y
C
R
T
G
S
L
C
S
L
E
Site 105
S1104
K
D
E
A
L
T
E
S
D
E
H
F
S
T
K
Site 106
T1110
E
S
D
E
H
F
S
T
K
L
M
Y
E
V
V
Site 107
Y1114
H
F
S
T
K
L
M
Y
E
V
V
D
N
S
S
Site 108
Y1167
P
D
V
R
L
F
K
Y
L
P
H
H
S
A
H
Site 109
S1172
F
K
Y
L
P
H
H
S
A
H
S
S
Q
L
D
Site 110
S1176
P
H
H
S
A
H
S
S
Q
L
D
A
D
S
W
Site 111
S1182
S
S
Q
L
D
A
D
S
W
I
E
N
D
S
L
Site 112
S1188
D
S
W
I
E
N
D
S
L
S
V
D
K
H
G
Site 113
S1190
W
I
E
N
D
S
L
S
V
D
K
H
G
D
D
Site 114
S1201
H
G
D
D
Q
P
D
S
S
S
L
K
S
R
G
Site 115
S1202
G
D
D
Q
P
D
S
S
S
L
K
S
R
G
S
Site 116
S1203
D
D
Q
P
D
S
S
S
L
K
S
R
G
S
V
Site 117
S1206
P
D
S
S
S
L
K
S
R
G
S
V
H
S
A
Site 118
S1209
S
S
L
K
S
R
G
S
V
H
S
A
C
S
S
Site 119
S1212
K
S
R
G
S
V
H
S
A
C
S
S
E
H
K
Site 120
S1215
G
S
V
H
S
A
C
S
S
E
H
K
G
L
P
Site 121
S1216
S
V
H
S
A
C
S
S
E
H
K
G
L
P
M
Site 122
S1237
P
A
G
Q
V
F
N
S
S
S
G
T
Q
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation