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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RXRG
Full Name:
Retinoic acid receptor RXR-gamma
Alias:
Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma protein
Type:
Nucleus protein
Mass (Da):
50871
Number AA:
463
UniProt ID:
P48443
International Prot ID:
IPI00009736
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004886
GO:0005496
GO:0003707
PhosphoSite+
KinaseNET
Biological Process:
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
F
P
A
G
Y
G
G
S
P
G
H
T
G
S
T
Site 2
T22
Y
G
G
S
P
G
H
T
G
S
T
S
M
S
P
Site 3
S24
G
S
P
G
H
T
G
S
T
S
M
S
P
S
A
Site 4
S26
P
G
H
T
G
S
T
S
M
S
P
S
A
A
L
Site 5
S28
H
T
G
S
T
S
M
S
P
S
A
A
L
S
T
Site 6
S30
G
S
T
S
M
S
P
S
A
A
L
S
T
G
K
Site 7
S34
M
S
P
S
A
A
L
S
T
G
K
P
M
D
S
Site 8
T35
S
P
S
A
A
L
S
T
G
K
P
M
D
S
H
Site 9
S41
S
T
G
K
P
M
D
S
H
P
S
Y
T
D
T
Site 10
S44
K
P
M
D
S
H
P
S
Y
T
D
T
P
V
S
Site 11
Y45
P
M
D
S
H
P
S
Y
T
D
T
P
V
S
A
Site 12
T46
M
D
S
H
P
S
Y
T
D
T
P
V
S
A
P
Site 13
T48
S
H
P
S
Y
T
D
T
P
V
S
A
P
R
T
Site 14
S51
S
Y
T
D
T
P
V
S
A
P
R
T
L
S
A
Site 15
T74
G
S
P
Y
R
V
I
T
S
A
M
G
P
P
S
Site 16
S75
S
P
Y
R
V
I
T
S
A
M
G
P
P
S
G
Site 17
S98
N
L
V
A
P
P
S
S
Q
L
N
V
V
N
S
Site 18
S105
S
Q
L
N
V
V
N
S
V
S
S
S
E
D
I
Site 19
S109
V
V
N
S
V
S
S
S
E
D
I
K
P
L
P
Site 20
Y126
P
G
I
G
N
M
N
Y
P
S
T
S
P
G
S
Site 21
S128
I
G
N
M
N
Y
P
S
T
S
P
G
S
L
V
Site 22
T129
G
N
M
N
Y
P
S
T
S
P
G
S
L
V
K
Site 23
S130
N
M
N
Y
P
S
T
S
P
G
S
L
V
K
H
Site 24
S133
Y
P
S
T
S
P
G
S
L
V
K
H
I
C
A
Site 25
S147
A
I
C
G
D
R
S
S
G
K
H
Y
G
V
Y
Site 26
Y151
D
R
S
S
G
K
H
Y
G
V
Y
S
C
E
G
Site 27
Y154
S
G
K
H
Y
G
V
Y
S
C
E
G
C
K
G
Site 28
T166
C
K
G
F
F
K
R
T
I
R
K
D
L
I
Y
Site 29
Y173
T
I
R
K
D
L
I
Y
T
C
R
D
N
K
D
Site 30
S216
V
Q
E
E
R
Q
R
S
R
E
R
A
E
S
E
Site 31
S222
R
S
R
E
R
A
E
S
E
A
E
C
A
T
S
Site 32
S229
S
E
A
E
C
A
T
S
G
H
E
D
M
P
V
Site 33
T250
E
L
A
V
E
P
K
T
E
S
Y
G
D
M
N
Site 34
Y253
V
E
P
K
T
E
S
Y
G
D
M
N
M
E
N
Site 35
S291
A
K
R
I
P
H
F
S
D
L
T
L
E
D
Q
Site 36
T294
I
P
H
F
S
D
L
T
L
E
D
Q
V
I
L
Site 37
S313
W
N
E
L
L
I
A
S
F
S
H
R
S
V
S
Site 38
S318
I
A
S
F
S
H
R
S
V
S
V
Q
D
G
I
Site 39
S336
T
G
L
H
V
H
R
S
S
A
H
S
A
G
V
Site 40
S337
G
L
H
V
H
R
S
S
A
H
S
A
G
V
G
Site 41
S356
R
V
L
T
E
L
V
S
K
M
K
D
M
Q
M
Site 42
S366
K
D
M
Q
M
D
K
S
E
L
G
C
L
R
A
Site 43
S385
N
P
D
A
K
G
L
S
N
P
S
E
V
E
T
Site 44
T392
S
N
P
S
E
V
E
T
L
R
E
K
V
Y
A
Site 45
Y398
E
T
L
R
E
K
V
Y
A
T
L
E
A
Y
T
Site 46
Y404
V
Y
A
T
L
E
A
Y
T
K
Q
K
Y
P
E
Site 47
Y409
E
A
Y
T
K
Q
K
Y
P
E
Q
P
G
R
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation