KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SLC6A8
Full Name:
Sodium- and chloride-dependent creatine transporter 1
Alias:
CRTR; CT1; SC6A8; Solute carrier family 6 (neurotransmitter transporter, creatine) member 8; Solute carrier family 6 member 8
Type:
Transporter
Mass (Da):
70523
Number AA:
635
UniProt ID:
P48029
International Prot ID:
IPI00007582
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005309
GO:0031402
PhosphoSite+
KinaseNET
Biological Process:
GO:0015881
GO:0006936
GO:0006836
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
K
K
S
A
E
N
G
I
Y
S
Site 2
Y11
K
S
A
E
N
G
I
Y
S
V
S
G
D
E
K
Site 3
S12
S
A
E
N
G
I
Y
S
V
S
G
D
E
K
K
Site 4
S14
E
N
G
I
Y
S
V
S
G
D
E
K
K
G
P
Site 5
T42
D
G
P
V
G
L
G
T
P
G
G
R
L
A
V
Site 6
T54
L
A
V
P
P
R
E
T
W
T
R
Q
M
D
F
Site 7
Y80
G
N
V
W
R
F
P
Y
L
C
Y
K
N
G
G
Site 8
Y83
W
R
F
P
Y
L
C
Y
K
N
G
G
G
V
F
Site 9
S208
D
Q
L
A
D
R
R
S
P
V
I
E
F
W
E
Site 10
S222
E
N
K
V
L
R
L
S
G
G
L
E
V
P
G
Site 11
Y262
K
S
T
G
K
I
V
Y
F
T
A
T
F
P
Y
Site 12
Y291
G
A
L
D
G
I
I
Y
Y
L
K
P
D
W
S
Site 13
Y292
A
L
D
G
I
I
Y
Y
L
K
P
D
W
S
K
Site 14
S298
Y
Y
L
K
P
D
W
S
K
L
G
S
P
Q
V
Site 15
S302
P
D
W
S
K
L
G
S
P
Q
V
W
I
D
A
Site 16
S329
G
A
L
T
A
L
G
S
Y
N
R
F
N
N
N
Site 17
Y330
A
L
T
A
L
G
S
Y
N
R
F
N
N
N
C
Site 18
S375
A
E
Q
G
V
H
I
S
K
V
A
E
S
G
P
Site 19
Y437
L
D
L
L
P
A
S
Y
Y
F
R
F
Q
R
E
Site 20
Y438
D
L
L
P
A
S
Y
Y
F
R
F
Q
R
E
I
Site 21
Y475
Y
V
F
Q
L
F
D
Y
Y
S
A
S
G
T
T
Site 22
S479
L
F
D
Y
Y
S
A
S
G
T
T
L
L
W
Q
Site 23
T481
D
Y
Y
S
A
S
G
T
T
L
L
W
Q
A
F
Site 24
Y547
V
Y
Y
E
P
L
V
Y
N
N
T
Y
V
Y
P
Site 25
Y551
P
L
V
Y
N
N
T
Y
V
Y
P
W
W
G
E
Site 26
Y606
W
G
L
H
H
L
E
Y
R
A
Q
D
A
D
V
Site 27
T617
D
A
D
V
R
G
L
T
T
L
T
P
V
S
E
Site 28
T618
A
D
V
R
G
L
T
T
L
T
P
V
S
E
S
Site 29
T620
V
R
G
L
T
T
L
T
P
V
S
E
S
S
K
Site 30
S623
L
T
T
L
T
P
V
S
E
S
S
K
V
V
V
Site 31
S625
T
L
T
P
V
S
E
S
S
K
V
V
V
V
E
Site 32
S626
L
T
P
V
S
E
S
S
K
V
V
V
V
E
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation