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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CAPZA2
Full Name:
F-actin-capping protein subunit alpha-2
Alias:
CAPPA2; Capping protein (actin filament) muscle Z-line, alpha 2; CAPZ; CapZ alpha-2; CAZA2
Type:
Cytoskeletal protein, F-actin capping protein complex protein
Mass (Da):
32949
Number AA:
286
UniProt ID:
P47755
International Prot ID:
IPI00026182
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008290
GO:0005737
GO:0008290
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
GO:0051693
GO:0006928
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
D
L
E
E
Q
L
S
D
E
E
K
V
R
I
Site 2
T63
Q
Y
N
L
D
Q
F
T
P
V
K
I
E
G
Y
Site 3
T106
D
H
L
R
K
E
A
T
D
P
R
P
C
E
V
Site 4
S119
E
V
E
N
A
V
E
S
W
R
T
S
V
E
T
Site 5
S123
A
V
E
S
W
R
T
S
V
E
T
A
L
R
A
Site 6
T126
S
W
R
T
S
V
E
T
A
L
R
A
Y
V
K
Site 7
Y131
V
E
T
A
L
R
A
Y
V
K
E
H
Y
P
N
Site 8
Y136
R
A
Y
V
K
E
H
Y
P
N
G
V
C
T
V
Site 9
Y144
P
N
G
V
C
T
V
Y
G
K
K
I
D
G
Q
Site 10
T180
W
R
S
E
W
K
F
T
I
T
P
S
T
T
Q
Site 11
T182
S
E
W
K
F
T
I
T
P
S
T
T
Q
V
V
Site 12
Y198
I
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
Site 13
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Site 14
S208
D
G
N
V
Q
L
V
S
H
K
D
I
Q
D
S
Site 15
S215
S
H
K
D
I
Q
D
S
L
T
V
S
N
E
V
Site 16
T217
K
D
I
Q
D
S
L
T
V
S
N
E
V
Q
T
Site 17
S219
I
Q
D
S
L
T
V
S
N
E
V
Q
T
A
K
Site 18
T249
A
I
S
E
N
Y
Q
T
M
S
D
T
T
F
K
Site 19
S251
S
E
N
Y
Q
T
M
S
D
T
T
F
K
A
L
Site 20
T253
N
Y
Q
T
M
S
D
T
T
F
K
A
L
R
R
Site 21
T265
L
R
R
Q
L
P
V
T
R
T
K
I
D
W
N
Site 22
Y277
D
W
N
K
I
L
S
Y
K
I
G
K
E
M
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation