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Updated November 2019
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Protein Info
Short Name:
UTRN
Full Name:
Utrophin
Alias:
DMDL; DRP; DRP1; Dystrophin-related protein 1; UTRO
Type:
Cytoskeletal protein, dystrophin complex
Mass (Da):
394466
Number AA:
3433
UniProt ID:
P46939
International Prot ID:
IPI00009329
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0005624
GO:0045211
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0008270
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006936
GO:0007517
GO:0006936
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y4
_
_
_
_
M
A
K
Y
G
E
H
E
A
S
P
Site 2
S10
K
Y
G
E
H
E
A
S
P
D
N
G
Q
N
E
Site 3
S19
D
N
G
Q
N
E
F
S
D
I
I
K
S
R
S
Site 4
S24
E
F
S
D
I
I
K
S
R
S
D
E
H
N
D
Site 5
S26
S
D
I
I
K
S
R
S
D
E
H
N
D
V
Q
Site 6
S46
K
W
I
N
A
R
F
S
K
S
G
K
P
P
I
Site 7
S48
I
N
A
R
F
S
K
S
G
K
P
P
I
N
D
Site 8
T58
P
P
I
N
D
M
F
T
D
L
K
D
G
R
K
Site 9
S77
L
E
G
L
T
G
T
S
L
P
K
E
R
G
S
Site 10
S84
S
L
P
K
E
R
G
S
T
R
V
H
A
L
N
Site 11
T85
L
P
K
E
R
G
S
T
R
V
H
A
L
N
N
Site 12
S145
D
V
M
K
D
V
M
S
D
L
Q
Q
T
N
S
Site 13
S152
S
D
L
Q
Q
T
N
S
E
K
I
L
L
S
W
Site 14
S158
N
S
E
K
I
L
L
S
W
V
R
Q
T
T
R
Site 15
T163
L
L
S
W
V
R
Q
T
T
R
P
Y
S
Q
V
Site 16
T164
L
S
W
V
R
Q
T
T
R
P
Y
S
Q
V
N
Site 17
Y167
V
R
Q
T
T
R
P
Y
S
Q
V
N
V
L
N
Site 18
S168
R
Q
T
T
R
P
Y
S
Q
V
N
V
L
N
F
Site 19
S206
W
D
K
V
V
K
M
S
P
I
E
R
L
E
H
Site 20
S216
E
R
L
E
H
A
F
S
K
A
Q
T
Y
L
G
Site 21
T220
H
A
F
S
K
A
Q
T
Y
L
G
I
E
K
L
Site 22
Y273
V
E
T
L
P
R
K
Y
K
K
E
C
E
E
E
Site 23
S286
E
E
A
I
N
I
Q
S
T
A
P
E
E
E
H
Site 24
S295
A
P
E
E
E
H
E
S
P
R
A
E
T
P
S
Site 25
T300
H
E
S
P
R
A
E
T
P
S
T
V
T
E
V
Site 26
S302
S
P
R
A
E
T
P
S
T
V
T
E
V
D
M
Site 27
T303
P
R
A
E
T
P
S
T
V
T
E
V
D
M
D
Site 28
S313
E
V
D
M
D
L
D
S
Y
Q
I
A
L
E
E
Site 29
Y314
V
D
M
D
L
D
S
Y
Q
I
A
L
E
E
V
Site 30
S327
E
V
L
T
W
L
L
S
A
E
D
T
F
Q
E
Site 31
T331
W
L
L
S
A
E
D
T
F
Q
E
Q
D
D
I
Site 32
S339
F
Q
E
Q
D
D
I
S
D
D
V
E
E
V
K
Site 33
T360
E
A
F
M
M
E
L
T
A
H
Q
S
S
V
G
Site 34
S364
M
E
L
T
A
H
Q
S
S
V
G
S
V
L
Q
Site 35
S365
E
L
T
A
H
Q
S
S
V
G
S
V
L
Q
A
Site 36
S368
A
H
Q
S
S
V
G
S
V
L
Q
A
G
N
Q
Site 37
T381
N
Q
L
I
T
Q
G
T
L
S
D
E
E
E
F
Site 38
S383
L
I
T
Q
G
T
L
S
D
E
E
E
F
E
I
Site 39
S408
W
E
A
L
R
V
E
S
M
D
R
Q
S
R
L
Site 40
S413
V
E
S
M
D
R
Q
S
R
L
H
D
V
L
M
Site 41
T435
Q
Q
L
S
A
W
L
T
L
T
E
E
R
I
Q
Site 42
T437
L
S
A
W
L
T
L
T
E
E
R
I
Q
K
M
Site 43
S455
P
L
D
D
D
V
K
S
L
Q
K
L
L
E
E
Site 44
S465
K
L
L
E
E
H
K
S
L
Q
S
D
L
E
A
Site 45
S567
F
K
D
Q
K
E
L
S
V
S
V
R
R
L
A
Site 46
S569
D
Q
K
E
L
S
V
S
V
R
R
L
A
I
L
Site 47
T586
D
M
E
M
K
R
Q
T
L
D
Q
L
S
E
I
Site 48
S591
R
Q
T
L
D
Q
L
S
E
I
G
Q
D
V
G
Site 49
S604
V
G
Q
L
L
D
N
S
K
A
S
K
K
I
N
Site 50
S612
K
A
S
K
K
I
N
S
D
S
E
E
L
T
Q
Site 51
S614
S
K
K
I
N
S
D
S
E
E
L
T
Q
R
W
Site 52
T618
N
S
D
S
E
E
L
T
Q
R
W
D
S
L
V
Site 53
S623
E
L
T
Q
R
W
D
S
L
V
Q
R
L
E
D
Site 54
S631
L
V
Q
R
L
E
D
S
S
N
Q
V
T
Q
A
Site 55
S632
V
Q
R
L
E
D
S
S
N
Q
V
T
Q
A
V
Site 56
T636
E
D
S
S
N
Q
V
T
Q
A
V
A
K
L
G
Site 57
S645
A
V
A
K
L
G
M
S
Q
I
P
Q
K
D
L
Site 58
T655
P
Q
K
D
L
L
E
T
V
R
V
R
E
Q
A
Site 59
T664
R
V
R
E
Q
A
I
T
K
K
S
K
Q
E
L
Site 60
S696
K
K
K
F
D
A
I
S
A
E
L
L
N
W
I
Site 61
T713
W
K
T
A
I
Q
T
T
E
I
K
E
Y
M
K
Site 62
Y718
Q
T
T
E
I
K
E
Y
M
K
M
Q
D
T
S
Site 63
T724
E
Y
M
K
M
Q
D
T
S
E
M
K
K
K
L
Site 64
S725
Y
M
K
M
Q
D
T
S
E
M
K
K
K
L
K
Site 65
T751
R
A
D
E
L
N
Q
T
G
Q
I
L
V
E
Q
Site 66
T766
M
G
K
E
G
L
P
T
E
E
I
K
N
V
L
Site 67
S778
N
V
L
E
K
V
S
S
E
W
K
N
V
S
Q
Site 68
S784
S
S
E
W
K
N
V
S
Q
H
L
E
D
L
E
Site 69
Y803
L
Q
E
D
I
N
A
Y
F
K
Q
L
D
E
L
Site 70
S825
E
E
W
V
K
H
T
S
I
S
E
S
S
R
Q
Site 71
S827
W
V
K
H
T
S
I
S
E
S
S
R
Q
S
L
Site 72
S829
K
H
T
S
I
S
E
S
S
R
Q
S
L
P
S
Site 73
S830
H
T
S
I
S
E
S
S
R
Q
S
L
P
S
L
Site 74
S833
I
S
E
S
S
R
Q
S
L
P
S
L
K
D
S
Site 75
S836
S
S
R
Q
S
L
P
S
L
K
D
S
C
Q
R
Site 76
S840
S
L
P
S
L
K
D
S
C
Q
R
E
L
T
N
Site 77
T846
D
S
C
Q
R
E
L
T
N
L
L
G
L
H
P
Site 78
S861
K
I
E
M
A
R
A
S
C
S
A
L
M
S
Q
Site 79
S863
E
M
A
R
A
S
C
S
A
L
M
S
Q
P
S
Site 80
S867
A
S
C
S
A
L
M
S
Q
P
S
A
P
D
F
Site 81
S870
S
A
L
M
S
Q
P
S
A
P
D
F
V
Q
R
Site 82
S881
F
V
Q
R
G
F
D
S
F
L
G
R
Y
Q
A
Site 83
Y886
F
D
S
F
L
G
R
Y
Q
A
V
Q
E
A
V
Site 84
Y912
K
G
Q
P
G
H
A
Y
L
E
T
L
K
T
L
Site 85
T918
A
Y
L
E
T
L
K
T
L
K
D
V
L
N
D
Site 86
S926
L
K
D
V
L
N
D
S
E
N
K
A
Q
V
S
Site 87
S933
S
E
N
K
A
Q
V
S
L
N
V
L
N
D
L
Site 88
T952
K
A
L
Q
E
K
K
T
L
D
E
I
L
E
N
Site 89
Y986
H
P
D
V
E
K
L
Y
K
Q
E
F
D
D
V
Site 90
S1005
N
K
L
K
V
L
V
S
K
D
L
H
L
L
E
Site 91
T1026
R
A
F
E
A
D
S
T
V
I
E
K
W
M
D
Site 92
S1060
Q
R
Q
L
D
Q
C
S
A
F
V
N
E
I
E
Site 93
T1081
K
N
M
K
E
I
E
T
N
L
R
S
G
P
V
Site 94
Y1102
V
Q
T
R
L
G
D
Y
Q
T
Q
L
E
K
L
Site 95
T1104
T
R
L
G
D
Y
Q
T
Q
L
E
K
L
S
K
Site 96
S1118
K
E
I
A
T
Q
K
S
R
L
S
E
S
Q
E
Site 97
S1121
A
T
Q
K
S
R
L
S
E
S
Q
E
K
A
A
Site 98
S1123
Q
K
S
R
L
S
E
S
Q
E
K
A
A
N
L
Site 99
Y1148
M
T
Q
A
E
E
E
Y
L
E
R
D
F
E
Y
Site 100
Y1155
Y
L
E
R
D
F
E
Y
K
S
P
E
E
L
E
Site 101
S1157
E
R
D
F
E
Y
K
S
P
E
E
L
E
S
A
Site 102
S1163
K
S
P
E
E
L
E
S
A
V
E
E
M
K
R
Site 103
T1227
R
I
R
G
K
C
H
T
L
E
E
V
W
S
C
Site 104
S1258
T
L
E
E
R
M
K
S
T
E
V
L
P
E
K
Site 105
T1259
L
E
E
R
M
K
S
T
E
V
L
P
E
K
T
Site 106
T1266
T
E
V
L
P
E
K
T
D
A
V
N
E
A
L
Site 107
S1275
A
V
N
E
A
L
E
S
L
E
S
V
L
R
H
Site 108
S1278
E
A
L
E
S
L
E
S
V
L
R
H
P
A
D
Site 109
T1288
R
H
P
A
D
N
R
T
Q
I
R
E
L
G
Q
Site 110
S1316
E
K
L
E
A
F
N
S
R
Y
E
D
L
S
H
Site 111
Y1318
L
E
A
F
N
S
R
Y
E
D
L
S
H
L
A
Site 112
S1322
N
S
R
Y
E
D
L
S
H
L
A
E
S
K
Q
Site 113
S1327
D
L
S
H
L
A
E
S
K
Q
I
S
L
E
K
Site 114
S1331
L
A
E
S
K
Q
I
S
L
E
K
Q
L
Q
V
Site 115
T1342
Q
L
Q
V
L
R
E
T
D
Q
M
L
Q
V
L
Site 116
Y1363
L
D
K
Q
L
T
T
Y
L
T
D
R
I
D
A
Site 117
T1365
K
Q
L
T
T
Y
L
T
D
R
I
D
A
F
Q
Site 118
S1400
E
L
R
R
N
M
R
S
Q
P
L
T
S
P
E
Site 119
T1404
N
M
R
S
Q
P
L
T
S
P
E
S
R
T
A
Site 120
S1405
M
R
S
Q
P
L
T
S
P
E
S
R
T
A
R
Site 121
S1408
Q
P
L
T
S
P
E
S
R
T
A
R
G
G
S
Site 122
T1410
L
T
S
P
E
S
R
T
A
R
G
G
S
Q
M
Site 123
S1415
S
R
T
A
R
G
G
S
Q
M
D
V
L
Q
R
Site 124
S1428
Q
R
K
L
R
E
V
S
T
K
F
Q
L
F
Q
Site 125
Y1482
L
D
K
C
M
K
L
Y
K
T
L
S
E
V
K
Site 126
T1484
K
C
M
K
L
Y
K
T
L
S
E
V
K
L
E
Site 127
S1486
M
K
L
Y
K
T
L
S
E
V
K
L
E
V
E
Site 128
T1498
E
V
E
T
V
I
K
T
G
R
H
I
V
Q
K
Site 129
T1508
H
I
V
Q
K
Q
Q
T
D
N
P
K
G
M
D
Site 130
T1519
K
G
M
D
E
Q
L
T
S
L
K
V
L
Y
N
Site 131
S1520
G
M
D
E
Q
L
T
S
L
K
V
L
Y
N
D
Site 132
S1543
K
Q
D
L
E
R
A
S
Q
L
A
R
K
M
K
Site 133
S1555
K
M
K
K
E
A
A
S
L
S
E
W
L
S
A
Site 134
S1557
K
K
E
A
A
S
L
S
E
W
L
S
A
T
E
Site 135
T1563
L
S
E
W
L
S
A
T
E
T
E
L
V
Q
K
Site 136
T1565
E
W
L
S
A
T
E
T
E
L
V
Q
K
S
T
Site 137
S1571
E
T
E
L
V
Q
K
S
T
S
E
G
L
L
G
Site 138
S1573
E
L
V
Q
K
S
T
S
E
G
L
L
G
D
L
Site 139
T1582
G
L
L
G
D
L
D
T
E
I
S
W
A
K
N
Site 140
S1585
G
D
L
D
T
E
I
S
W
A
K
N
V
L
K
Site 141
T1603
K
R
K
A
D
L
N
T
I
T
E
S
S
A
A
Site 142
T1683
D
E
I
E
K
K
P
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K
Q
E
E
I
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Site 143
S1684
E
I
E
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K
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E
E
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V
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Site 144
S1695
E
I
V
K
R
L
V
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L
D
D
A
N
L
Site 145
S1720
I
L
M
N
A
R
G
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V
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Site 146
S1721
L
M
N
A
R
G
S
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L
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E
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Site 147
S1741
N
R
N
F
E
K
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A
K
Site 148
S1746
K
V
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H
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K
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K
L
L
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A
Q
Site 149
Y1757
L
I
A
Q
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P
L
Y
Q
C
L
V
T
T
E
Site 150
S1773
F
E
T
G
V
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F
S
D
L
E
K
L
E
N
Site 151
S1796
V
E
K
H
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E
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S
D
E
D
E
K
M
D
Site 152
S1806
D
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Site 153
S1861
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L
Site 154
S1865
Q
L
A
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L
P
T
D
Y
Site 155
S1889
C
M
D
D
V
E
L
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L
N
V
P
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L
N
Site 156
Y1900
P
E
L
N
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A
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F
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F
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E
Site 157
S1904
T
A
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K
Site 158
S1909
D
F
S
F
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E
D
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K
N
I
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D
Q
Site 159
T1949
E
A
I
Q
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T
L
T
Q
L
N
A
K
Site 160
T1951
I
Q
I
R
D
T
L
T
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L
N
A
K
W
D
Site 161
Y1964
W
D
R
I
N
R
M
Y
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R
K
G
C
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Site 162
S2026
Q
E
L
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P
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F
A
Site 163
S2027
E
L
E
V
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A
A
Site 164
S2031
G
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A
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R
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Site 165
S2047
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Site 166
S2052
K
L
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L
A
Site 167
S2083
Q
P
R
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Q
V
M
K
Y
R
Site 168
T2112
H
A
M
Q
K
R
S
T
T
E
L
G
E
N
L
Site 169
T2113
A
M
Q
K
R
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T
T
E
L
G
E
N
L
Q
Site 170
T2126
L
Q
E
L
R
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L
T
Q
E
M
E
V
H
A
Site 171
S2148
R
T
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M
L
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K
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L
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L
P
Site 172
S2151
L
E
M
L
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K
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S
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P
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Site 173
S2153
M
L
S
D
K
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P
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K
I
Site 174
S2161
L
P
E
R
D
K
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E
S
L
R
T
V
N
Site 175
S2163
E
R
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K
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R
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V
N
M
T
Site 176
T2166
K
I
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M
T
W
N
K
Site 177
T2181
I
C
R
E
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P
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T
L
K
E
C
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Q
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Site 178
S2191
E
C
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Q
T
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A
Site 179
S2193
I
Q
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P
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T
R
I
A
A
H
Site 180
T2195
E
P
S
S
V
S
Q
T
R
I
A
A
H
P
N
Site 181
S2213
V
V
L
V
S
S
A
S
D
I
P
V
Q
S
H
Site 182
S2219
A
S
D
I
P
V
Q
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R
T
S
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I
S
Site 183
S2223
P
V
Q
S
H
R
T
S
E
I
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I
P
A
D
Site 184
S2226
S
H
R
T
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S
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P
A
D
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D
K
Site 185
T2234
I
P
A
D
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D
K
T
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T
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L
A
D
W
Site 186
T2265
D
V
E
E
I
N
K
T
V
S
R
M
K
I
T
Site 187
Y2285
Q
R
H
P
Q
L
D
Y
V
F
T
L
A
Q
N
Site 188
T2288
P
Q
L
D
Y
V
F
T
L
A
Q
N
L
K
N
Site 189
S2298
Q
N
L
K
N
K
A
S
S
S
D
M
R
T
A
Site 190
S2300
L
K
N
K
A
S
S
S
D
M
R
T
A
I
T
Site 191
T2304
A
S
S
S
D
M
R
T
A
I
T
E
K
L
E
Site 192
T2320
V
K
N
Q
W
D
G
T
Q
H
G
V
E
L
R
Site 193
T2348
W
D
D
H
R
E
E
T
E
E
L
M
R
K
Y
Site 194
Y2355
T
E
E
L
M
R
K
Y
E
A
R
L
Y
I
L
Site 195
Y2360
R
K
Y
E
A
R
L
Y
I
L
Q
Q
A
R
R
Site 196
T2371
Q
A
R
R
D
P
L
T
K
Q
I
S
D
N
Q
Site 197
S2375
D
P
L
T
K
Q
I
S
D
N
Q
I
L
L
Q
Site 198
S2407
K
L
L
E
E
Y
G
S
D
D
T
R
N
V
K
Site 199
T2410
E
E
Y
G
S
D
D
T
R
N
V
K
E
T
T
Site 200
T2416
D
T
R
N
V
K
E
T
T
E
Y
L
K
T
S
Site 201
Y2419
N
V
K
E
T
T
E
Y
L
K
T
S
W
I
N
Site 202
T2422
E
T
T
E
Y
L
K
T
S
W
I
N
L
K
Q
Site 203
S2430
S
W
I
N
L
K
Q
S
I
A
D
R
Q
N
A
Site 204
T2444
A
L
E
A
E
W
R
T
V
Q
A
S
R
R
D
Site 205
S2448
E
W
R
T
V
Q
A
S
R
R
D
L
E
N
F
Site 206
S2473
V
N
V
L
V
D
A
S
H
R
E
N
A
L
Q
Site 207
S2508
A
H
N
D
I
F
K
S
I
D
G
N
R
Q
K
Site 208
T2527
L
G
N
S
E
E
A
T
M
L
Q
H
R
L
D
Site 209
S2547
W
N
D
L
K
A
K
S
A
S
I
R
A
H
L
Site 210
S2549
D
L
K
A
K
S
A
S
I
R
A
H
L
E
A
Site 211
S2567
K
W
N
R
L
L
M
S
L
E
E
L
I
K
W
Site 212
Y2599
V
P
A
L
Q
L
Q
Y
D
H
C
K
A
L
R
Site 213
S2615
E
L
K
E
K
E
Y
S
V
L
N
A
V
D
Q
Site 214
S2644
E
P
R
R
N
L
Q
S
K
T
E
L
T
P
E
Site 215
T2649
L
Q
S
K
T
E
L
T
P
E
E
R
A
Q
K
Site 216
S2665
A
K
A
M
R
K
Q
S
S
E
V
K
E
K
W
Site 217
S2666
K
A
M
R
K
Q
S
S
E
V
K
E
K
W
E
Site 218
S2674
E
V
K
E
K
W
E
S
L
N
A
V
T
S
N
Site 219
S2680
E
S
L
N
A
V
T
S
N
W
Q
K
Q
V
D
Site 220
S2712
A
D
M
K
E
A
E
S
V
R
N
G
W
K
P
Site 221
S2727
V
G
D
L
L
I
D
S
L
Q
D
H
I
E
K
Site 222
T2751
P
I
N
F
K
V
K
T
V
N
D
L
S
S
Q
Site 223
S2756
V
K
T
V
N
D
L
S
S
Q
L
S
P
L
D
Site 224
S2757
K
T
V
N
D
L
S
S
Q
L
S
P
L
D
L
Site 225
S2760
N
D
L
S
S
Q
L
S
P
L
D
L
H
P
S
Site 226
S2767
S
P
L
D
L
H
P
S
L
K
M
S
R
Q
L
Site 227
S2771
L
H
P
S
L
K
M
S
R
Q
L
D
D
L
N
Site 228
S2787
R
W
K
L
L
Q
V
S
V
D
D
R
L
K
Q
Site 229
S2805
A
H
R
D
F
G
P
S
S
Q
H
F
L
S
T
Site 230
S2806
H
R
D
F
G
P
S
S
Q
H
F
L
S
T
S
Site 231
S2811
P
S
S
Q
H
F
L
S
T
S
V
Q
L
P
W
Site 232
T2812
S
S
Q
H
F
L
S
T
S
V
Q
L
P
W
Q
Site 233
S2813
S
Q
H
F
L
S
T
S
V
Q
L
P
W
Q
R
Site 234
S2821
V
Q
L
P
W
Q
R
S
I
S
H
N
K
V
P
Site 235
Y2830
S
H
N
K
V
P
Y
Y
I
N
H
Q
T
Q
T
Site 236
S2851
K
M
T
E
L
F
Q
S
L
A
D
L
N
N
V
Site 237
S2861
D
L
N
N
V
R
F
S
A
Y
R
T
A
I
K
Site 238
T2865
V
R
F
S
A
Y
R
T
A
I
K
I
R
R
L
Site 239
T2886
D
L
L
E
L
S
T
T
N
E
I
F
K
Q
H
Site 240
S2903
N
Q
N
D
Q
L
L
S
V
P
D
V
I
N
C
Site 241
Y2943
L
N
W
L
L
N
V
Y
D
T
G
R
T
G
K
Site 242
T2945
W
L
L
N
V
Y
D
T
G
R
T
G
K
I
R
Site 243
S2964
K
I
G
L
M
S
L
S
K
G
L
L
E
E
K
Site 244
Y2972
K
G
L
L
E
E
K
Y
R
Y
L
F
K
E
V
Site 245
Y2974
L
L
E
E
K
Y
R
Y
L
F
K
E
V
A
G
Site 246
S3019
G
G
S
N
I
E
P
S
V
R
S
C
F
Q
Q
Site 247
S3048
W
M
H
L
E
P
Q
S
M
V
W
L
P
V
L
Site 248
Y3091
R
S
L
K
H
F
N
Y
D
V
C
Q
S
C
F
Site 249
Y3111
A
K
G
H
K
L
H
Y
P
M
V
E
Y
C
I
Site 250
Y3116
L
H
Y
P
M
V
E
Y
C
I
P
T
T
S
G
Site 251
T3130
G
E
D
V
R
D
F
T
K
V
L
K
N
K
F
Site 252
Y3142
N
K
F
R
S
K
K
Y
F
A
K
H
P
R
L
Site 253
T3168
D
N
L
E
T
P
I
T
L
I
S
M
W
P
E
Site 254
Y3177
I
S
M
W
P
E
H
Y
D
P
S
Q
S
P
Q
Site 255
S3182
E
H
Y
D
P
S
Q
S
P
Q
L
F
H
D
D
Site 256
T3190
P
Q
L
F
H
D
D
T
H
S
R
I
E
Q
Y
Site 257
S3192
L
F
H
D
D
T
H
S
R
I
E
Q
Y
A
T
Site 258
Y3197
T
H
S
R
I
E
Q
Y
A
T
R
L
A
Q
M
Site 259
T3199
S
R
I
E
Q
Y
A
T
R
L
A
Q
M
E
R
Site 260
S3210
Q
M
E
R
T
N
G
S
F
L
T
D
S
S
S
Site 261
T3213
R
T
N
G
S
F
L
T
D
S
S
S
T
T
G
Site 262
S3215
N
G
S
F
L
T
D
S
S
S
T
T
G
S
V
Site 263
S3217
S
F
L
T
D
S
S
S
T
T
G
S
V
E
D
Site 264
T3219
L
T
D
S
S
S
T
T
G
S
V
E
D
E
H
Site 265
S3221
D
S
S
S
T
T
G
S
V
E
D
E
H
A
L
Site 266
Y3232
E
H
A
L
I
Q
Q
Y
C
Q
T
L
G
G
E
Site 267
T3235
L
I
Q
Q
Y
C
Q
T
L
G
G
E
S
P
V
Site 268
S3240
C
Q
T
L
G
G
E
S
P
V
S
Q
P
Q
S
Site 269
S3243
L
G
G
E
S
P
V
S
Q
P
Q
S
P
A
Q
Site 270
S3247
S
P
V
S
Q
P
Q
S
P
A
Q
I
L
K
S
Site 271
S3254
S
P
A
Q
I
L
K
S
V
E
R
E
E
R
G
Site 272
Y3281
Q
R
N
L
Q
V
E
Y
E
Q
L
K
D
Q
H
Site 273
S3297
R
R
G
L
P
V
G
S
P
P
E
S
I
I
S
Site 274
S3301
P
V
G
S
P
P
E
S
I
I
S
P
H
H
T
Site 275
S3304
S
P
P
E
S
I
I
S
P
H
H
T
S
E
D
Site 276
T3308
S
I
I
S
P
H
H
T
S
E
D
S
E
L
I
Site 277
S3309
I
I
S
P
H
H
T
S
E
D
S
E
L
I
A
Site 278
S3344
D
H
N
K
Q
L
E
S
Q
L
H
R
L
R
Q
Site 279
S3358
Q
L
L
E
Q
P
E
S
D
S
R
I
N
G
V
Site 280
S3360
L
E
Q
P
E
S
D
S
R
I
N
G
V
S
P
Site 281
S3366
D
S
R
I
N
G
V
S
P
W
A
S
P
Q
H
Site 282
S3370
N
G
V
S
P
W
A
S
P
Q
H
S
A
L
S
Site 283
S3374
P
W
A
S
P
Q
H
S
A
L
S
Y
S
L
D
Site 284
S3377
S
P
Q
H
S
A
L
S
Y
S
L
D
P
D
A
Site 285
S3379
Q
H
S
A
L
S
Y
S
L
D
P
D
A
S
G
Site 286
S3385
Y
S
L
D
P
D
A
S
G
P
Q
F
H
Q
A
Site 287
S3405
L
A
P
P
H
D
T
S
T
D
L
T
E
V
M
Site 288
T3409
H
D
T
S
T
D
L
T
E
V
M
E
Q
I
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation