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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMC4
Full Name:
26S protease regulatory subunit 6B
Alias:
MB67 interacting protein; MIP224; Proteasome 26S subunit ATPase 4; PRS6; PRS6B; TAT-binding protein-7; TBP-7
Type:
Protease (proteasomal subunit)
Mass (Da):
47366
Number AA:
418
UniProt ID:
P43686
International Prot ID:
IPI00020042
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005634
GO:0000502
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051436
GO:0051437
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
Q
D
E
I
P
A
L
S
V
S
R
P
Q
T
G
Site 2
S21
E
I
P
A
L
S
V
S
R
P
Q
T
G
L
S
Site 3
T25
L
S
V
S
R
P
Q
T
G
L
S
F
L
G
P
Site 4
S28
S
R
P
Q
T
G
L
S
F
L
G
P
E
P
E
Site 5
Y41
P
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Site 6
S42
E
D
L
E
D
L
Y
S
R
Y
K
K
L
Q
Q
Site 7
S84
E
E
V
K
R
I
Q
S
I
P
L
V
I
G
Q
Site 8
S105
Q
N
T
A
I
V
G
S
T
T
G
S
N
Y
Y
Site 9
Y111
G
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
Site 10
Y112
S
T
T
G
S
N
Y
Y
V
R
I
L
S
T
I
Site 11
S117
N
Y
Y
V
R
I
L
S
T
I
D
R
E
L
L
Site 12
T118
Y
Y
V
R
I
L
S
T
I
D
R
E
L
L
K
Site 13
S129
E
L
L
K
P
N
A
S
V
A
L
H
K
H
S
Site 14
S150
L
P
P
E
A
D
S
S
I
M
M
L
T
S
D
Site 15
T155
D
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
Site 16
S156
S
S
I
M
M
L
T
S
D
Q
K
P
D
V
M
Site 17
Y164
D
Q
K
P
D
V
M
Y
A
D
I
G
G
M
D
Site 18
T186
E
A
V
E
L
P
L
T
H
F
E
L
Y
K
Q
Site 19
Y191
P
L
T
H
F
E
L
Y
K
Q
I
G
I
D
P
Site 20
Y205
P
P
R
G
V
L
M
Y
G
P
P
G
C
G
K
Site 21
Y239
G
S
E
F
V
Q
K
Y
L
G
E
G
P
R
M
Site 22
T279
T
K
R
F
D
A
Q
T
G
A
D
R
E
V
Q
Site 23
T316
M
A
T
N
R
A
D
T
L
D
P
A
L
L
R
Site 24
S346
R
Q
K
R
L
I
F
S
T
I
T
S
K
M
N
Site 25
T347
Q
K
R
L
I
F
S
T
I
T
S
K
M
N
L
Site 26
S350
L
I
F
S
T
I
T
S
K
M
N
L
S
E
E
Site 27
Y363
E
E
V
D
L
E
D
Y
V
A
R
P
D
K
I
Site 28
S371
V
A
R
P
D
K
I
S
G
A
D
I
N
S
I
Site 29
S377
I
S
G
A
D
I
N
S
I
C
Q
E
S
G
M
Site 30
Y403
A
K
D
F
E
K
A
Y
K
T
V
I
K
K
D
Site 31
T405
D
F
E
K
A
Y
K
T
V
I
K
K
D
E
Q
Site 32
Y417
D
E
Q
E
H
E
F
Y
K
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation