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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPD2
Full Name:
Glycerol-3-phosphate dehydrogenase, mitochondrial
Alias:
GDH2; Glycerol-3-phosphate dehydrogenase 2 (mitochondrial); Glycerol-3-phosphate dehydrogenase, mitochondrial; GPDH-M; GPDM; GPD-M; MtGPD
Type:
Calcium-binding protein; Mitochondrial; Lipid Metabolism - glycerophospholipid; EC 1.1.99.5; Oxidoreductase
Mass (Da):
80853
Number AA:
727
UniProt ID:
P43304
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009331
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0004368
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y30
G
L
S
Q
F
A
H
Y
R
R
K
Q
M
N
L
Site 2
Y39
R
K
Q
M
N
L
A
Y
V
K
A
A
D
C
I
Site 3
S47
V
K
A
A
D
C
I
S
E
P
V
N
R
E
P
Site 4
S56
P
V
N
R
E
P
P
S
R
E
A
Q
L
L
T
Site 5
T63
S
R
E
A
Q
L
L
T
L
Q
N
T
S
E
F
Site 6
S104
L
V
E
R
D
D
F
S
S
G
T
S
S
R
S
Site 7
S105
V
E
R
D
D
F
S
S
G
T
S
S
R
S
T
Site 8
T107
R
D
D
F
S
S
G
T
S
S
R
S
T
K
L
Site 9
S108
D
D
F
S
S
G
T
S
S
R
S
T
K
L
I
Site 10
S109
D
F
S
S
G
T
S
S
R
S
T
K
L
I
H
Site 11
S111
S
S
G
T
S
S
R
S
T
K
L
I
H
G
G
Site 12
T112
S
G
T
S
S
R
S
T
K
L
I
H
G
G
V
Site 13
Y121
L
I
H
G
G
V
R
Y
L
Q
K
A
I
M
K
Site 14
Y134
M
K
L
D
I
E
Q
Y
R
M
V
K
E
A
L
Site 15
S191
A
G
S
N
C
L
K
S
S
Y
V
L
S
K
S
Site 16
S192
G
S
N
C
L
K
S
S
Y
V
L
S
K
S
R
Site 17
Y193
S
N
C
L
K
S
S
Y
V
L
S
K
S
R
A
Site 18
S196
L
K
S
S
Y
V
L
S
K
S
R
A
L
E
H
Site 19
S198
S
S
Y
V
L
S
K
S
R
A
L
E
H
F
P
Site 20
Y218
K
L
V
G
A
I
V
Y
Y
D
G
Q
H
N
D
Site 21
S251
A
N
Y
M
E
V
V
S
L
L
K
K
T
D
P
Site 22
T260
L
K
K
T
D
P
Q
T
G
K
V
R
V
S
G
Site 23
S266
Q
T
G
K
V
R
V
S
G
A
R
C
K
D
V
Site 24
T275
A
R
C
K
D
V
L
T
G
Q
E
F
D
V
R
Site 25
T290
A
K
C
V
I
N
A
T
G
P
F
T
D
S
V
Site 26
T294
I
N
A
T
G
P
F
T
D
S
V
R
K
M
D
Site 27
S296
A
T
G
P
F
T
D
S
V
R
K
M
D
D
K
Site 28
Y322
V
H
I
V
M
P
G
Y
Y
S
P
E
S
M
G
Site 29
Y323
H
I
V
M
P
G
Y
Y
S
P
E
S
M
G
L
Site 30
S327
P
G
Y
Y
S
P
E
S
M
G
L
L
D
P
A
Site 31
T357
T
I
A
G
T
T
D
T
P
T
D
V
T
H
H
Site 32
T359
A
G
T
T
D
T
P
T
D
V
T
H
H
P
I
Site 33
T362
T
D
T
P
T
D
V
T
H
H
P
I
P
S
E
Site 34
S384
N
E
V
R
N
Y
L
S
C
D
V
E
V
R
R
Site 35
T406
S
G
I
R
P
L
V
T
D
P
K
S
A
D
T
Site 36
S410
P
L
V
T
D
P
K
S
A
D
T
Q
S
I
S
Site 37
T413
T
D
P
K
S
A
D
T
Q
S
I
S
R
N
H
Site 38
S415
P
K
S
A
D
T
Q
S
I
S
R
N
H
V
V
Site 39
T438
T
I
A
G
G
K
W
T
T
Y
R
S
M
A
E
Site 40
T439
I
A
G
G
K
W
T
T
Y
R
S
M
A
E
D
Site 41
Y440
A
G
G
K
W
T
T
Y
R
S
M
A
E
D
T
Site 42
S462
H
N
L
K
A
G
P
S
R
T
V
G
L
F
L
Site 43
S476
L
Q
G
G
K
D
W
S
P
T
L
Y
I
R
L
Site 44
T478
G
G
K
D
W
S
P
T
L
Y
I
R
L
V
Q
Site 45
Y480
K
D
W
S
P
T
L
Y
I
R
L
V
Q
D
Y
Site 46
Y487
Y
I
R
L
V
Q
D
Y
G
L
E
S
E
V
A
Site 47
S513
F
E
V
A
K
M
A
S
V
T
G
K
R
W
P
Site 48
T515
V
A
K
M
A
S
V
T
G
K
R
W
P
I
V
Site 49
Y532
R
L
V
S
E
F
P
Y
I
E
A
E
V
K
Y
Site 50
Y586
R
E
L
N
W
D
D
Y
K
K
Q
E
Q
L
E
Site 51
T594
K
K
Q
E
Q
L
E
T
A
R
K
F
L
Y
Y
Site 52
Y600
E
T
A
R
K
F
L
Y
Y
E
M
G
Y
K
S
Site 53
Y601
T
A
R
K
F
L
Y
Y
E
M
G
Y
K
S
R
Site 54
Y605
F
L
Y
Y
E
M
G
Y
K
S
R
S
E
Q
L
Site 55
S607
Y
Y
E
M
G
Y
K
S
R
S
E
Q
L
T
D
Site 56
S609
E
M
G
Y
K
S
R
S
E
Q
L
T
D
R
S
Site 57
T613
K
S
R
S
E
Q
L
T
D
R
S
E
I
S
L
Site 58
S616
S
E
Q
L
T
D
R
S
E
I
S
L
L
P
S
Site 59
S619
L
T
D
R
S
E
I
S
L
L
P
S
D
I
D
Site 60
S623
S
E
I
S
L
L
P
S
D
I
D
R
Y
K
K
Site 61
Y628
L
P
S
D
I
D
R
Y
K
K
R
F
H
K
F
Site 62
T663
N
V
Q
M
D
E
N
T
L
H
E
I
L
N
E
Site 63
S699
Q
K
G
R
V
S
G
S
R
L
A
I
L
M
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation