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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRAT
Full Name:
Carnitine O-acetyltransferase
Alias:
CACP; Carnitine acetylase; Carnitine acetyltransferase; CAT1; EC 2.3.1.; EC 2.3.1.7
Type:
Membrane, Mitochondrial inner membrane, Endoplasmic reticulum, Mitochondrion, Peroxisome protein
Mass (Da):
70858
Number AA:
626
UniProt ID:
P43155
International Prot ID:
IPI00016457
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0005743
GO:0005777
Uniprot
OncoNet
Molecular Function:
GO:0004092
PhosphoSite+
KinaseNET
Biological Process:
GO:0015980
GO:0033540
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
P
F
S
L
M
K
A
S
S
R
F
K
A
H
Q
Site 2
S26
F
S
L
M
K
A
S
S
R
F
K
A
H
Q
D
Site 3
S46
P
V
P
P
L
Q
Q
S
L
D
H
Y
L
K
A
Site 4
Y50
L
Q
Q
S
L
D
H
Y
L
K
A
L
Q
P
I
Site 5
S59
K
A
L
Q
P
I
V
S
E
E
E
W
A
H
T
Site 6
T66
S
E
E
E
W
A
H
T
K
Q
L
V
D
E
F
Site 7
S76
L
V
D
E
F
Q
A
S
G
G
V
G
E
R
L
Site 8
T94
L
E
R
R
A
R
K
T
E
N
W
L
S
E
W
Site 9
Y107
E
W
W
L
K
T
A
Y
L
Q
Y
R
Q
P
V
Site 10
Y110
L
K
T
A
Y
L
Q
Y
R
Q
P
V
V
I
Y
Site 11
Y117
Y
R
Q
P
V
V
I
Y
S
S
P
G
V
M
L
Site 12
T157
K
V
M
I
D
N
E
T
L
P
V
E
Y
L
G
Site 13
Y173
K
P
L
C
M
N
Q
Y
Y
Q
I
L
S
S
C
Site 14
Y174
P
L
C
M
N
Q
Y
Y
Q
I
L
S
S
C
R
Site 15
S178
N
Q
Y
Y
Q
I
L
S
S
C
R
V
P
G
P
Site 16
S179
Q
Y
Y
Q
I
L
S
S
C
R
V
P
G
P
K
Site 17
T189
V
P
G
P
K
Q
D
T
V
S
N
F
S
K
T
Site 18
S191
G
P
K
Q
D
T
V
S
N
F
S
K
T
K
K
Site 19
T196
T
V
S
N
F
S
K
T
K
K
P
P
T
H
I
Site 20
T201
S
K
T
K
K
P
P
T
H
I
T
V
V
H
N
Site 21
T204
K
K
P
P
T
H
I
T
V
V
H
N
Y
Q
F
Site 22
Y217
Q
F
F
E
L
D
V
Y
H
S
D
G
T
P
L
Site 23
S219
F
E
L
D
V
Y
H
S
D
G
T
P
L
T
A
Site 24
T222
D
V
Y
H
S
D
G
T
P
L
T
A
D
Q
I
Site 25
T225
H
S
D
G
T
P
L
T
A
D
Q
I
F
V
Q
Site 26
T252
K
E
P
V
G
I
L
T
S
N
H
R
N
S
W
Site 27
S253
E
P
V
G
I
L
T
S
N
H
R
N
S
W
A
Site 28
S275
K
D
K
V
N
R
D
S
V
R
S
I
Q
K
S
Site 29
S278
V
N
R
D
S
V
R
S
I
Q
K
S
I
F
T
Site 30
S296
D
A
T
M
P
R
V
S
E
D
V
Y
R
S
H
Site 31
Y300
P
R
V
S
E
D
V
Y
R
S
H
V
A
G
Q
Site 32
S314
Q
M
L
H
G
G
G
S
R
L
N
S
G
N
R
Site 33
S318
G
G
G
S
R
L
N
S
G
N
R
W
F
D
K
Site 34
Y341
D
G
S
C
G
L
V
Y
E
H
A
A
A
E
G
Site 35
T362
L
D
Y
V
I
E
Y
T
K
K
P
E
L
V
R
Site 36
S370
K
K
P
E
L
V
R
S
P
L
V
P
L
P
M
Site 37
T386
K
K
L
R
F
N
I
T
P
E
I
K
S
D
I
Site 38
S391
N
I
T
P
E
I
K
S
D
I
E
K
A
K
Q
Site 39
S401
E
K
A
K
Q
N
L
S
I
M
I
Q
D
L
D
Site 40
S424
F
G
K
D
F
P
K
S
E
K
L
S
P
D
A
Site 41
S428
F
P
K
S
E
K
L
S
P
D
A
F
I
Q
M
Site 42
Y441
Q
M
A
L
Q
L
A
Y
Y
R
I
Y
G
Q
A
Site 43
Y445
Q
L
A
Y
Y
R
I
Y
G
Q
A
C
A
T
Y
Site 44
Y452
Y
G
Q
A
C
A
T
Y
E
S
A
S
L
R
M
Site 45
S456
C
A
T
Y
E
S
A
S
L
R
M
F
H
L
G
Site 46
T467
F
H
L
G
R
T
D
T
I
R
S
A
S
M
D
Site 47
S470
G
R
T
D
T
I
R
S
A
S
M
D
S
L
T
Site 48
S472
T
D
T
I
R
S
A
S
M
D
S
L
T
F
V
Site 49
T477
S
A
S
M
D
S
L
T
F
V
K
A
M
D
D
Site 50
S485
F
V
K
A
M
D
D
S
S
V
T
E
H
Q
K
Site 51
S486
V
K
A
M
D
D
S
S
V
T
E
H
Q
K
V
Site 52
Y506
A
V
Q
A
H
R
G
Y
T
D
R
A
I
R
G
Site 53
T507
V
Q
A
H
R
G
Y
T
D
R
A
I
R
G
E
Site 54
S554
M
H
F
H
L
S
T
S
Q
V
P
A
K
T
D
Site 55
Y578
P
D
G
Y
G
V
C
Y
N
P
M
E
A
H
I
Site 56
S590
A
H
I
N
F
S
L
S
A
Y
N
S
C
A
E
Site 57
Y592
I
N
F
S
L
S
A
Y
N
S
C
A
E
T
N
Site 58
S594
F
S
L
S
A
Y
N
S
C
A
E
T
N
A
A
Site 59
T598
A
Y
N
S
C
A
E
T
N
A
A
R
L
A
H
Site 60
Y606
N
A
A
R
L
A
H
Y
L
E
K
A
L
L
D
Site 61
S620
D
M
R
A
L
L
Q
S
H
P
R
A
K
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation