PhosphoNET

           
Protein Info 
   
Short Name:  MLLT3
Full Name:  Protein AF-9
Alias:  AF9; AF-9; ALL1 fused gene from chromosome 9; Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila); Myeloid/lymphoid or mixed-lineage leukemia (trithorax homologue, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3; Translocated to, 3 (AF9); YEATS domain-containing 3; YEATS3
Type:  Cytoplasm, Nucleus protein
Mass (Da):  63351
Number AA:  568
UniProt ID:  P42568
International Prot ID:  IPI00000033
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T24AQVRKKPTVEGFTHD
Site 2S58VVFHLHESFPRPKRV
Site 3Y71RVCKDPPYKVEESGY
Site 4Y88FILPIEVYFKNKEEP
Site 5Y102PRKVRFDYDLFLHLE
Site 6T123HLRCEKLTFNNPTED
Site 7S145AGGDPNRSIHTSSSS
Site 8T148DPNRSIHTSSSSSSS
Site 9S149PNRSIHTSSSSSSSS
Site 10S150NRSIHTSSSSSSSSS
Site 11S151RSIHTSSSSSSSSSS
Site 12S152SIHTSSSSSSSSSSS
Site 13S153IHTSSSSSSSSSSSS
Site 14S154HTSSSSSSSSSSSSS
Site 15S155TSSSSSSSSSSSSSS
Site 16S156SSSSSSSSSSSSSSS
Site 17S184SSSSSSSSSSSSSST
Site 18S185SSSSSSSSSSSSSTS
Site 19S186SSSSSSSSSSSSTSF
Site 20S187SSSSSSSSSSSTSFS
Site 21S188SSSSSSSSSSTSFSK
Site 22S189SSSSSSSSSTSFSKP
Site 23S190SSSSSSSSTSFSKPH
Site 24T191SSSSSSSTSFSKPHK
Site 25S192SSSSSSTSFSKPHKL
Site 26S194SSSSTSFSKPHKLMK
Site 27S211KEKPSKDSREHKSAF
Site 28S216KDSREHKSAFKEPSR
Site 29S222KSAFKEPSRDHNKSS
Site 30S228PSRDHNKSSKESSKK
Site 31S229SRDHNKSSKESSKKP
Site 32S233NKSSKESSKKPKENK
Site 33S260FKEPKPMSKEPKPDS
Site 34S267SKEPKPDSNLLTITS
Site 35T271KPDSNLLTITSGQDK
Site 36S274SNLLTITSGQDKKAP
Site 37S282GQDKKAPSKRPPISD
Site 38S288PSKRPPISDSEELSA
Site 39S290KRPPISDSEELSAKK
Site 40S294ISDSEELSAKKRKKS
Site 41S301SAKKRKKSSSEALFK
Site 42S302AKKRKKSSSEALFKS
Site 43S303KKRKKSSSEALFKSF
Site 44S309SSEALFKSFSSAPPL
Site 45T319SAPPLILTCSADKKQ
Site 46S321PPLILTCSADKKQIK
Site 47S331KKQIKDKSHVKMGKV
Site 48S345VKIESETSEKKKSTL
Site 49S350ETSEKKKSTLPPFDD
Site 50T351TSEKKKSTLPPFDDI
Site 51S364DIVDPNDSDVEENIS
Site 52S371SDVEENISSKSDSEQ
Site 53S372DVEENISSKSDSEQP
Site 54S374EENISSKSDSEQPSP
Site 55S376NISSKSDSEQPSPAS
Site 56S380KSDSEQPSPASSSSS
Site 57S383SEQPSPASSSSSSSS
Site 58S384EQPSPASSSSSSSSS
Site 59S385QPSPASSSSSSSSSF
Site 60S386PSPASSSSSSSSSFT
Site 61S387SPASSSSSSSSSFTP
Site 62S388PASSSSSSSSSFTPS
Site 63S389ASSSSSSSSSFTPSQ
Site 64S390SSSSSSSSSFTPSQT
Site 65S391SSSSSSSSFTPSQTR
Site 66T393SSSSSSFTPSQTRQQ
Site 67S395SSSSFTPSQTRQQGP
Site 68S405RQQGPLRSIMKDLHS
Site 69S412SIMKDLHSDDNEEES
Site 70S419SDDNEEESDEVEDND
Site 71S429VEDNDNDSEMERPVN
Site 72S440RPVNRGGSRSRRVSL
Site 73S442VNRGGSRSRRVSLSD
Site 74S446GSRSRRVSLSDGSDS
Site 75S448RSRRVSLSDGSDSES
Site 76S451RVSLSDGSDSESSSA
Site 77S453SLSDGSDSESSSASS
Site 78S455SDGSDSESSSASSPL
Site 79S456DGSDSESSSASSPLH
Site 80S457GSDSESSSASSPLHH
Site 81S459DSESSSASSPLHHEP
Site 82S460SESSSASSPLHHEPP
Site 83T473PPPPLLKTNNNQILE
Site 84S483NQILEVKSPIKQSKS
Site 85S488VKSPIKQSKSDKQIK
Site 86S490SPIKQSKSDKQIKNG
Site 87Y503NGECDKAYLDELVEL
Site 88T516ELHRRLMTLRERHIL
Site 89S549TFDFDLCSLDKTTVR
Site 90T553DLCSLDKTTVRKLQS
Site 91T554LCSLDKTTVRKLQSY
Site 92Y561TVRKLQSYLETSGTS
Site 93T564KLQSYLETSGTS___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation