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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACTR1B
Full Name:
Beta-centractin
Alias:
Actin-related protein 1B; ACTY; ARP1 actin-related protein 1 homologue B, centractin beta; ARP1B; Centracti; CTRN2; PC3
Type:
Cytoskeletal protein
Mass (Da):
42293
Number AA:
376
UniProt ID:
P42025
International Prot ID:
IPI00029469
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005869
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
E
S
Y
D
I
I
A
N
Q
Site 2
Y4
_
_
_
_
M
E
S
Y
D
I
I
A
N
Q
P
Site 3
Y33
A
G
D
Q
I
P
K
Y
C
F
P
N
Y
V
G
Site 4
Y38
P
K
Y
C
F
P
N
Y
V
G
R
P
K
H
M
Site 5
T70
E
E
H
R
G
L
L
T
I
R
Y
P
M
E
H
Site 6
Y92
D
M
E
R
I
W
Q
Y
V
Y
S
K
D
Q
L
Site 7
T101
Y
S
K
D
Q
L
Q
T
F
S
E
E
H
P
V
Site 8
T111
E
E
H
P
V
L
L
T
E
A
P
L
N
P
S
Site 9
Y171
V
T
H
A
V
P
I
Y
E
G
F
A
M
P
H
Site 10
Y193
A
G
R
D
V
S
R
Y
L
R
L
L
L
R
K
Site 11
T207
K
E
G
V
D
F
H
T
S
A
E
F
E
V
V
Site 12
T216
A
E
F
E
V
V
R
T
I
K
E
R
A
C
Y
Site 13
Y223
T
I
K
E
R
A
C
Y
L
S
I
N
P
Q
K
Site 14
S225
K
E
R
A
C
Y
L
S
I
N
P
Q
K
D
E
Site 15
T236
Q
K
D
E
A
L
E
T
E
K
V
Q
Y
T
L
Site 16
Y241
L
E
T
E
K
V
Q
Y
T
L
P
D
G
S
T
Site 17
T242
E
T
E
K
V
Q
Y
T
L
P
D
G
S
T
L
Site 18
S247
Q
Y
T
L
P
D
G
S
T
L
D
V
G
P
A
Site 19
T248
Y
T
L
P
D
G
S
T
L
D
V
G
P
A
R
Site 20
S272
P
D
L
V
G
D
E
S
E
G
L
H
E
V
V
Site 21
S286
V
A
F
A
I
H
K
S
D
M
D
L
R
R
T
Site 22
S316
G
F
G
D
R
L
L
S
E
V
K
K
L
A
P
Site 23
Y338
S
A
P
Q
E
R
L
Y
S
T
W
I
G
G
S
Site 24
S339
A
P
Q
E
R
L
Y
S
T
W
I
G
G
S
I
Site 25
Y363
M
W
V
S
K
K
E
Y
E
E
D
G
S
R
A
Site 26
S368
K
E
Y
E
E
D
G
S
R
A
I
H
R
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation