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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC26A3
Full Name:
Chloride anion exchanger
Alias:
Chloride anion exchanger; CLD; Down-regulated in adenoma; DRA; S26A3; solute carrier family 26, member 3
Type:
Mass (Da):
84505
Number AA:
764
UniProt ID:
P40879
International Prot ID:
IPI00031036
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005624
Uniprot
OncoNet
Molecular Function:
GO:0031404
GO:0008271
GO:0003712
PhosphoSite+
KinaseNET
Biological Process:
GO:0007588
GO:0008272
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
Y
I
V
A
R
P
V
Y
S
T
N
A
F
E
E
Site 2
T18
V
A
R
P
V
Y
S
T
N
A
F
E
E
N
H
Site 3
T28
F
E
E
N
H
K
K
T
G
R
H
H
K
T
F
Site 4
T34
K
T
G
R
H
H
K
T
F
L
D
H
L
K
V
Site 5
S46
L
K
V
C
C
S
C
S
P
Q
K
A
K
R
I
Site 6
T155
A
V
P
D
R
N
A
T
T
L
G
L
P
N
N
Site 7
S163
T
L
G
L
P
N
N
S
N
N
S
S
L
L
D
Site 8
S167
P
N
N
S
N
N
S
S
L
L
D
D
E
R
V
Site 9
T238
Q
L
T
V
P
S
H
T
D
P
V
S
I
F
K
Site 10
S242
P
S
H
T
D
P
V
S
I
F
K
V
L
Y
S
Site 11
S252
K
V
L
Y
S
V
F
S
Q
I
E
K
T
N
I
Site 12
T330
P
G
F
Q
P
P
I
T
P
D
V
E
T
F
Q
Site 13
T335
P
I
T
P
D
V
E
T
F
Q
N
T
V
G
D
Site 14
Y365
A
S
V
Y
S
L
K
Y
D
Y
P
L
D
G
N
Site 15
Y367
V
Y
S
L
K
Y
D
Y
P
L
D
G
N
Q
E
Site 16
S398
F
A
G
S
T
A
L
S
R
S
A
V
Q
E
S
Site 17
S400
G
S
T
A
L
S
R
S
A
V
Q
E
S
T
G
Site 18
T503
L
L
T
I
V
F
R
T
Q
F
P
K
C
S
T
Site 19
S509
R
T
Q
F
P
K
C
S
T
L
A
N
I
G
R
Site 20
Y520
N
I
G
R
T
N
I
Y
K
N
K
K
D
Y
Y
Site 21
Y526
I
Y
K
N
K
K
D
Y
Y
D
M
Y
E
P
E
Site 22
Y527
Y
K
N
K
K
D
Y
Y
D
M
Y
E
P
E
G
Site 23
Y530
K
K
D
Y
Y
D
M
Y
E
P
E
G
V
K
I
Site 24
T600
G
F
I
C
T
V
D
T
I
K
D
S
D
E
E
Site 25
S604
T
V
D
T
I
K
D
S
D
E
E
L
D
N
N
Site 26
T623
L
D
Q
P
I
N
T
T
D
L
P
F
H
I
D
Site 27
S669
S
S
V
R
G
L
K
S
I
L
Q
E
F
I
R
Site 28
Y697
F
I
E
K
L
N
R
Y
E
F
F
D
G
E
V
Site 29
Y726
H
I
L
M
K
K
D
Y
S
T
S
K
F
N
P
Site 30
S727
I
L
M
K
K
D
Y
S
T
S
K
F
N
P
S
Site 31
T728
L
M
K
K
D
Y
S
T
S
K
F
N
P
S
Q
Site 32
S729
M
K
K
D
Y
S
T
S
K
F
N
P
S
Q
E
Site 33
S734
S
T
S
K
F
N
P
S
Q
E
K
D
G
K
I
Site 34
T744
K
D
G
K
I
D
F
T
I
N
T
N
G
G
L
Site 35
Y756
G
G
L
R
N
R
V
Y
E
V
P
V
E
T
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation