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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PBX3
Full Name:
Pre-B-cell leukemia transcription factor 3
Alias:
Homeobox PBX3
Type:
Transcription protein
Mass (Da):
47190
Number AA:
434
UniProt ID:
P40426
International Prot ID:
Isoforma - IPI00028417
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007387
GO:0007388
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T55
D
I
L
H
Q
I
M
T
I
T
D
Q
S
L
D
Site 2
S94
I
K
E
K
T
G
L
S
I
R
G
A
Q
E
E
Site 3
S121
M
L
L
A
E
G
V
S
G
P
E
K
G
G
G
Site 4
S139
A
A
A
A
A
A
A
S
G
G
S
S
D
N
S
Site 5
S143
A
A
A
S
G
G
S
S
D
N
S
I
E
H
S
Site 6
S146
S
G
G
S
S
D
N
S
I
E
H
S
D
Y
R
Site 7
S150
S
D
N
S
I
E
H
S
D
Y
R
A
K
L
T
Site 8
Y152
N
S
I
E
H
S
D
Y
R
A
K
L
T
Q
I
Site 9
T157
S
D
Y
R
A
K
L
T
Q
I
R
Q
I
Y
H
Site 10
Y163
L
T
Q
I
R
Q
I
Y
H
T
E
L
E
K
Y
Site 11
T165
Q
I
R
Q
I
Y
H
T
E
L
E
K
Y
E
Q
Site 12
Y170
Y
H
T
E
L
E
K
Y
E
Q
A
C
N
E
F
Site 13
S189
M
N
L
L
R
E
Q
S
R
T
R
P
I
S
P
Site 14
T191
L
L
R
E
Q
S
R
T
R
P
I
S
P
K
E
Site 15
S195
Q
S
R
T
R
P
I
S
P
K
E
I
E
R
M
Site 16
S211
G
I
I
H
R
K
F
S
S
I
Q
M
Q
L
K
Site 17
S212
I
I
H
R
K
F
S
S
I
Q
M
Q
L
K
Q
Site 18
S243
R
R
K
R
R
N
F
S
K
Q
A
T
E
I
L
Site 19
T247
R
N
F
S
K
Q
A
T
E
I
L
N
E
Y
F
Site 20
Y253
A
T
E
I
L
N
E
Y
F
Y
S
H
L
S
N
Site 21
Y255
E
I
L
N
E
Y
F
Y
S
H
L
S
N
P
Y
Site 22
S259
E
Y
F
Y
S
H
L
S
N
P
Y
P
S
E
E
Site 23
Y262
Y
S
H
L
S
N
P
Y
P
S
E
E
A
K
E
Site 24
S276
E
E
L
A
K
K
C
S
I
T
V
S
Q
V
S
Site 25
T278
L
A
K
K
C
S
I
T
V
S
Q
V
S
N
W
Site 26
S280
K
K
C
S
I
T
V
S
Q
V
S
N
W
F
G
Site 27
Y293
F
G
N
K
R
I
R
Y
K
K
N
I
G
K
F
Site 28
Y307
F
Q
E
E
A
N
L
Y
A
A
K
T
A
V
T
Site 29
T328
A
A
V
Q
N
N
Q
T
N
S
P
T
T
P
N
Site 30
S330
V
Q
N
N
Q
T
N
S
P
T
T
P
N
S
G
Site 31
T332
N
N
Q
T
N
S
P
T
T
P
N
S
G
S
S
Site 32
T333
N
Q
T
N
S
P
T
T
P
N
S
G
S
S
G
Site 33
S336
N
S
P
T
T
P
N
S
G
S
S
G
S
F
N
Site 34
S339
T
T
P
N
S
G
S
S
G
S
F
N
L
P
N
Site 35
S341
P
N
S
G
S
S
G
S
F
N
L
P
N
S
G
Site 36
S361
M
Q
S
L
N
G
D
S
Y
Q
G
S
Q
V
G
Site 37
Y362
Q
S
L
N
G
D
S
Y
Q
G
S
Q
V
G
A
Site 38
S365
N
G
D
S
Y
Q
G
S
Q
V
G
A
N
V
Q
Site 39
S373
Q
V
G
A
N
V
Q
S
Q
V
D
T
L
R
H
Site 40
T377
N
V
Q
S
Q
V
D
T
L
R
H
V
I
N
Q
Site 41
S389
I
N
Q
T
G
G
Y
S
D
G
L
G
G
N
S
Site 42
S396
S
D
G
L
G
G
N
S
L
Y
S
P
H
N
L
Site 43
Y398
G
L
G
G
N
S
L
Y
S
P
H
N
L
N
A
Site 44
S399
L
G
G
N
S
L
Y
S
P
H
N
L
N
A
N
Site 45
T413
N
G
G
W
Q
D
A
T
T
P
S
S
V
T
S
Site 46
T414
G
G
W
Q
D
A
T
T
P
S
S
V
T
S
P
Site 47
S416
W
Q
D
A
T
T
P
S
S
V
T
S
P
T
E
Site 48
S417
Q
D
A
T
T
P
S
S
V
T
S
P
T
E
G
Site 49
S420
T
T
P
S
S
V
T
S
P
T
E
G
P
G
S
Site 50
T422
P
S
S
V
T
S
P
T
E
G
P
G
S
V
H
Site 51
S427
S
P
T
E
G
P
G
S
V
H
S
D
T
S
N
Site 52
S430
E
G
P
G
S
V
H
S
D
T
S
N
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation