KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CCT-zeta
Full Name:
T-complex protein 1 subunit zeta
Alias:
Acute morphine dependence related protein 2; CCT6; CCTZ; Cctz1; CCT-zeta-1; Chaperonin containing TCP1, subunit 6A (zeta 1); HTR3; T-complex protein 1, zeta subunit; TCP-1-zeta; Tcp20; TCPZ; TTCP20
Type:
Chaperone protein
Mass (Da):
58024
Number AA:
531
UniProt ID:
P40227
International Prot ID:
IPI00027626
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0051082
PhosphoSite+
KinaseNET
Biological Process:
GO:0006457
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T88
A
T
A
Q
D
D
I
T
G
D
G
T
T
S
N
Site 2
Y109
L
L
K
Q
A
D
L
Y
I
S
E
G
L
H
P
Site 3
T120
G
L
H
P
R
I
I
T
E
G
F
E
A
A
K
Site 4
T147
S
R
E
M
D
R
E
T
L
I
D
V
A
R
T
Site 5
S200
I
M
E
M
K
H
K
S
E
T
D
T
S
L
I
Site 6
T204
K
H
K
S
E
T
D
T
S
L
I
R
G
L
V
Site 7
S205
H
K
S
E
T
D
T
S
L
I
R
G
L
V
L
Site 8
Y229
K
K
R
V
E
D
A
Y
I
L
T
C
N
V
S
Site 9
S236
Y
I
L
T
C
N
V
S
L
E
Y
E
K
T
E
Site 10
Y239
T
C
N
V
S
L
E
Y
E
K
T
E
V
N
S
Site 11
T242
V
S
L
E
Y
E
K
T
E
V
N
S
G
F
F
Site 12
S246
Y
E
K
T
E
V
N
S
G
F
F
Y
K
S
A
Site 13
Y250
E
V
N
S
G
F
F
Y
K
S
A
E
E
R
E
Site 14
S252
N
S
G
F
F
Y
K
S
A
E
E
R
E
K
L
Site 15
S285
K
R
K
V
C
G
D
S
D
K
G
F
V
V
I
Site 16
S301
Q
K
G
I
D
P
F
S
L
D
A
L
S
K
E
Site 17
T325
R
R
N
M
E
R
L
T
L
A
C
G
G
V
A
Site 18
S335
C
G
G
V
A
L
N
S
F
D
D
L
S
P
D
Site 19
S340
L
N
S
F
D
D
L
S
P
D
C
L
G
H
A
Site 20
Y351
L
G
H
A
G
L
V
Y
E
Y
T
L
G
E
E
Site 21
T354
A
G
L
V
Y
E
Y
T
L
G
E
E
K
F
T
Site 22
T361
T
L
G
E
E
K
F
T
F
I
E
K
C
N
N
Site 23
S371
E
K
C
N
N
P
R
S
V
T
L
L
I
K
G
Site 24
T373
C
N
N
P
R
S
V
T
L
L
I
K
G
P
N
Site 25
S455
P
K
V
L
A
Q
N
S
G
F
D
L
Q
E
T
Site 26
T462
S
G
F
D
L
Q
E
T
L
V
K
I
Q
A
E
Site 27
S471
V
K
I
Q
A
E
H
S
E
S
G
Q
L
V
G
Site 28
S473
I
Q
A
E
H
S
E
S
G
Q
L
V
G
V
D
Site 29
Y498
E
V
G
V
W
D
N
Y
C
V
K
K
Q
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation