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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIGA
Full Name:
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A
Alias:
EC 2.4.1.198; Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, GlcNAc-PI synthesis protein; Phosphatidylinositol-glycan biosynthesis, class A protein, PIG-A
Type:
Transferase, Glycan Biosynthesis and Metabolism group, Glycosylphosphatidylinositol(GPI)-anchor biosynthesis family, Glycan structures - biosynthesis 2 family
Mass (Da):
54127
Number AA:
484
UniProt ID:
P37287
International Prot ID:
IPI00020966
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005789
GO:0000506
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0017176
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0009893
GO:0016254
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
A
G
N
G
H
R
A
S
A
T
L
S
R
V
S
Site 2
T16
N
G
H
R
A
S
A
T
L
S
R
V
S
P
G
Site 3
S18
H
R
A
S
A
T
L
S
R
V
S
P
G
S
L
Site 4
S21
S
A
T
L
S
R
V
S
P
G
S
L
Y
T
C
Site 5
S24
L
S
R
V
S
P
G
S
L
Y
T
C
R
T
R
Site 6
Y26
R
V
S
P
G
S
L
Y
T
C
R
T
R
T
H
Site 7
T27
V
S
P
G
S
L
Y
T
C
R
T
R
T
H
N
Site 8
S51
P
N
M
G
G
V
E
S
H
I
Y
Q
L
S
Q
Site 9
S57
E
S
H
I
Y
Q
L
S
Q
C
L
I
E
R
G
Site 10
Y82
G
N
R
K
G
I
R
Y
L
T
S
G
L
K
V
Site 11
T84
R
K
G
I
R
Y
L
T
S
G
L
K
V
Y
Y
Site 12
T105
Y
N
Q
S
T
A
T
T
L
F
H
S
L
P
L
Site 13
T123
I
F
V
R
E
R
V
T
I
I
H
S
H
S
S
Site 14
S127
E
R
V
T
I
I
H
S
H
S
S
F
S
A
M
Site 15
S130
T
I
I
H
S
H
S
S
F
S
A
M
A
H
D
Site 16
T149
A
K
T
M
G
L
Q
T
V
F
T
D
H
S
L
Site 17
T192
S
Y
T
S
K
E
N
T
V
L
R
A
A
L
N
Site 18
T216
A
V
D
P
T
D
F
T
P
D
P
F
R
R
H
Site 19
S225
D
P
F
R
R
H
D
S
I
T
I
V
V
V
S
Site 20
Y278
L
E
E
V
R
E
R
Y
Q
L
H
D
R
V
R
Site 21
S354
L
C
E
P
S
V
K
S
L
C
E
G
L
E
K
Site 22
S368
K
A
I
F
Q
L
K
S
G
T
L
P
A
P
E
Site 23
Y398
A
E
R
T
E
K
V
Y
D
R
V
S
V
E
A
Site 24
S418
K
R
L
D
R
L
I
S
H
C
G
P
V
T
G
Site 25
T465
T
G
P
R
G
A
W
T
N
N
Y
S
H
S
K
Site 26
Y468
R
G
A
W
T
N
N
Y
S
H
S
K
R
G
G
Site 27
S469
G
A
W
T
N
N
Y
S
H
S
K
R
G
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation